Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

2016 Vol. 34, No. 3

Cover
Display Method:
Role of cyclooxygenases in radiation enteropathy
TAO Yulong, YANG Hong, TAO Xia
2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
Abstract:
Gastrointestinal tract is one of the most sensitive organs exposed to ionizing radiation. Radiation enteropathy is a hot topic in radiobiological field. Cumulative evidences demonstrated that cyclooxygenases (COXs) might contribute substantially to a...
Research progress of drug-loading gold nanoparticles
ZHANG Xin, LIU Ying, FENG Nianping
2016, 34(3): 196-200,236. doi: 10.3969/j.issn.1006-0111.2016.03.002
Abstract:
In recent years, as a novel drug delivery system, gold nanoparticles have attracted widespread attention. Because of their special physicochemical properties, such as quantum size effect, unique optical phenomenon, easily reacting with thiol compound...
Study of total celosins on liver protection in different liver damage model
TANG Ying, LIANG Lin, GUO Meili
2016, 34(3): 201-205,282. doi: 10.3969/j.issn.1006-0111.2016.03.003
Abstract:
Objective To study the liver protection of total celosins (CES) in different liver damage models. Method Acute liver damage mouse model, chronic liver damage rat model and immune liver damage mouse model were established for this study. Liver func...
Protective effects and mechanism of Asiatic Acid on traumatic brain injury
GU Shenyong, ZHU Qiuzhen, WANG Jing, LIU Yulan, ZHANG Yue, RUI Yaocheng, ZHANG Yuefan, LI Tiejun
2016, 34(3): 206-209,288. doi: 10.3969/j.issn.1006-0111.2016.03.004
Abstract:
Objective To study the protective effects and mechanism of Asiatic Acid (AA) on traumatic brain injury. Methods The closed craniocerebral injury model made by the weight-drop method and fluid percussion brain injury model were used in the study. B...
Sensitized cytotoxic effects of dexamethasone or radiation on multiple myeloma cells by chloroquine
FU Hui, TAO Yulong, NI Min, LI Dongjie, SHEN Fuming
2016, 34(3): 210-214. doi: 10.3969/j.issn.1006-0111.2016.03.005
Abstract:
Objective To investigate the role and possible mechanism of combination use of chloroquine (CQ) with either dexamethasone (DEX) or radiation on multiple myeloma (MM) cell line U266. Methods Cell viability of U266 treated with CQ alone, or CQ combi...
Genotoxicity evaluation of triptolide
TIAN Yijun, ZHENG Yiwen, ZHU Yuping, ZHANG Xiaofang, ZONG Ying, LU Guocai
2016, 34(3): 215-218. doi: 10.3969/j.issn.1006-0111.2016.03.006
Abstract:
Objective To study the genotoxicity of triptolide, an important active component of Tripterygium wilfordii Hook f. Methods Ames test, in vitro chromosomal aberration test of CHO cell and in vivo micronucleus assay were performed to investigate the...
Wentilactone A inhibition of migration of small cell lung carcinoma NCI-H1688 cell line
JIANG Wenli, HUANG Caiguo
2016, 34(3): 219-222,274. doi: 10.3969/j.issn.1006-0111.2016.03.007
Abstract:
Objective To investigate mechanism of Wentilactone A (WA) inhibition of small cell lung cancer(SCLC) cell line NCI-H1688 migration. Methods The migration and proliferation were analyzed by wounding-healing assay and MTT assay[3- (4, 5-Dimethylthia...
Inhibition effects of fungal immunomodulatory proteins from Ganoderma spp. on different gastric cancer cell lines in vitro
XU Yan, HU Minghui, GAO Beirong, ZHOU Xuanwei
2016, 34(3): 223-226,277. doi: 10.3969/j.issn.1006-0111.2016.03.008
Abstract:
Objective To study the cell proliferative effects of fungal immunomodulatory proteins from Ganoderma spp. on 26 gastric cancer cell lines in vitro. Method 26 human gastric cancer cell lines were treated with FIPs by MTS assay. The average optical ...
Analysis on ADR monitoring of Chinese medical institutions based-on bibliometric
MENG Lei, LUAN Zhipeng, CHU Wengong
2016, 34(3): 227-231. doi: 10.3969/j.issn.1006-0111.2016.03.009
Abstract:
Objective To discuss the development of ADR monitoring in Chinese medical institutions by the bibliometrics. Methods Literatures from CNKI.net, VIP and Wanfang Database were retrieved, then to compliant literatures were screened according to inclu...
The inspiration of American pharmacists training system
GAO Yue, LIU Zhaoyuan, FAN Li, DONG Guoqiang, ZHOU Zheng, LUO Yungen, ZHANG Hongwu
2016, 34(3): 232-236. doi: 10.3969/j.issn.1006-0111.2016.03.010
Abstract:
Taking Pharm.D. degree education in School of Pharmacy, University of Pittsburgh as an example, this paper introduced the American pharmacists training system, degree setting for service-oriented pharmacy students, training objective, course design, ...
Study on Sini decoction in treatment of hypothyroidism by metabonomic method
JIA Yuting, JIN Yuchen, TAN Guangguo
2016, 34(3): 237-240,248. doi: 10.3969/j.issn.1006-0111.2016.03.011
Abstract:
Objective To evaluate therapeutic effects of Sini decoction (SND) on hypothyroidism based on serum metabonomics method. Methods Twenty-four rats were randomly divided into three groups including sham group, surgery-induced hypothyroid model group ...
Evaluation of pharmacogenetic algorithms in dose prediction under low dose warfarin anticoagulation in mechanical cardiac valve replacement patients
CUI Li, LIU Jun
2016, 34(3): 241-244,270. doi: 10.3969/j.issn.1006-0111.2016.03.012
Abstract:
Objective Our aim is to assess the performance of warfarin pharmacogenetic algorithms in patients post mechanical cardiac valve replacement under low dose warfarin anticoagulation. Methods Based on the specified standard, from January 2012 to Octo...
Identification and determination of scutellarin in compound granule tetrandra
ZHANG Shuyu, XU Jianjiang, YU Yanli, BI Yunsheng, ZHAO Wenjing, LIU Qian, LIU Tongqi
2016, 34(3): 245-248. doi: 10.3969/j.issn.1006-0111.2016.03.013
Abstract:
Objective To develop the methods for identification and determination of scutellarin in compound Granule Tetrandra. Methods A TLC method was used to identify quality for scutellarin, and a HPLC method was used to determine the content of scutellar...
Study on HPLC fingerprint of Ginseng Radix et Rhizoma Rubra
GAO Yanxia, SU Juan, JIN Huizi
2016, 34(3): 249-251,254. doi: 10.3969/j.issn.1006-0111.2016.03.014
Abstract:
Objective To establish the HPLC fingerprint of Ginseng Radix et Rhizoma Rubra for its quality control. Methods Sharpsil-T C18 column(4.6 mm×250 mm, 5 μm)was used with acetonitrile-water in gradient elution mode. The flow rate was 1.0 ml/min, the c...
Discussion on the purified water inspection methods in the Chinese Pharmacopoeia of edition 2010
LIU Qiang, SUN Zhiguo, CHEN Yi, CHEN Qi, HUANG Hualin, GAO Jing
2016, 34(3): 252-254. doi: 10.3969/j.issn.1006-0111.2016.03.015
Abstract:
Objective To modify the purified water analysis methods in the Chinese Pharmacopoeia (Vol.Ⅱ, Edition 2010), and mainly focus on the pH value determination, analysis of nitrate and nitrite, and the inspection of microorganism. Methods The usage of ...
Determination of valproate in serum by precolumn derivatization HPLC
CHEN Bi, HUANG Xiaoliang, LI Hui
2016, 34(3): 255-257. doi: 10.3969/j.issn.1006-0111.2016.03.016
Abstract:
Objective To establish a determination method for valprate in serum. Methods Serum sample was acidified by sulfuric acid and extracted with ethyl ether, cyclohexanecarboxylic acid was selected as an internal standard, α-bromoacetophenone as deriva...
Quality of control of compound chlorhexidine acetate ointment
HU Wenjun, DENG Zhaohui, LI Aihong, CI Wei
2016, 34(3): 258-260,266. doi: 10.3969/j.issn.1006-0111.2016.03.017
Abstract:
Objective To improve the standard of the quality control of compound chlorhexidine acetate ointment. Methods TLC was used to control the quality of menthol crystal and camphor. A method to determine chlorhexidine acetate and cocaine hydrochloride ...
Decreasing affinity of CAR-T cells targeting HER2 to increase therapeutic outcome against tumors
ZHANG Hao, YE Zhenlong, QIAN Qijun
2016, 34(3): 261-266. doi: 10.3969/j.issn.1006-0111.2016.03.018
Abstract:
Objective To investigate whether decreasing affinity of CAR-T cells can increase their therapeutic outcome or not. Methods Moderate affinity La-G3HER2-CAR and high affinity Ha-G3HER2-CAR were constructed, and electroporated to modify T cells. West...
Comparison of urapidil and nicardipine in the treatment of chronic renal failure patients with hypertensive emergencies
WU Rui, DONG Ziping, WANG Shengqi, QIN Jian
2016, 34(3): 267-270. doi: 10.3969/j.issn.1006-0111.2016.03.019
Abstract:
Objective To study the efficacies and adverse reactions of urapidil and nicardipine in the treatment of the chronic renal failure patients with hypertensive emergencies. Methods 59 chronic renal failure patients with hypertensive emergencies were ...
Analysis of anti-ulcerative drug use in patients undergoing thyroid operation during perioperative period
ZHANG Qiang, LI Jian, PENG Ran, LI Yongxian
2016, 34(3): 271-274. doi: 10.3969/j.issn.1006-0111.2016.03.020
Abstract:
Objective To investigate anti-ulcerative drug (AUD) utility in patients undergoing thyroid operation against stress ulcer (SU) during perioperative period. Methods A total of 393 patients undergoing arthroscopic operation during Jan. to Dec. 2013 ...
Observation and analysis of curative effect of the child bronchitis by adjuvant treatment of Xuanfeizhisou mixture
YE Zaiqing
2016, 34(3): 275-277. doi: 10.3969/j.issn.1006-0111.2016.03.021
Abstract:
Objective To observe the clinical efficacy and safety of Xuanfeizhisou mixture in the treatment of infantile bronchitis. Methods 120 cases of children with infantile bronchitis were randomly divided into observation group of 58 cases and control g...
Analysis on dynamic changes of pharmacy human resources in military hospitals in a region
LUAN Zhipeng, HUO Hua, GU Hongshuang, HUANG Haibo
2016, 34(3): 278-282. doi: 10.3969/j.issn.1006-0111.2016.03.022
Abstract:
Objective To provide a reference for optimizing pharmacy human resources allocation in military hospitals in a region. Methods Data of pharmacy human resources of 15 military hospitals in a region were collected from 2 pharmacy resources investiga...
Comparison of the medicine treatment level of military in patients in military hospital before and after the adjustment of the policy of military reasonable medicine treatment
ZHANG Hualin, CHU Cang, ZHANG Xiaodong, YANG Zhangwei, KUAI Liping
2016, 34(3): 283-288. doi: 10.3969/j.issn.1006-0111.2016.03.023
Abstract:
Objective To assess differences between the medicine treatment level of military inpatients in military hospital in 2009 and 2011, provide references for reasonable adjustments of health policy in future. Methods Medicine treatment data from acute...