2016 Vol. 34, No. 3
Display Method:
2016, 34(3): 193-195.
doi: 10.3969/j.issn.1006-0111.2016.03.001
Abstract:
Gastrointestinal tract is one of the most sensitive organs exposed to ionizing radiation. Radiation enteropathy is a hot topic in radiobiological field. Cumulative evidences demonstrated that cyclooxygenases (COXs) might contribute substantially to a...
Gastrointestinal tract is one of the most sensitive organs exposed to ionizing radiation. Radiation enteropathy is a hot topic in radiobiological field. Cumulative evidences demonstrated that cyclooxygenases (COXs) might contribute substantially to a...
2016, 34(3): 196-200,236.
doi: 10.3969/j.issn.1006-0111.2016.03.002
Abstract:
In recent years, as a novel drug delivery system, gold nanoparticles have attracted widespread attention. Because of their special physicochemical properties, such as quantum size effect, unique optical phenomenon, easily reacting with thiol compound...
In recent years, as a novel drug delivery system, gold nanoparticles have attracted widespread attention. Because of their special physicochemical properties, such as quantum size effect, unique optical phenomenon, easily reacting with thiol compound...
2016, 34(3): 201-205,282.
doi: 10.3969/j.issn.1006-0111.2016.03.003
Abstract:
Objective To study the liver protection of total celosins (CES) in different liver damage models. Method Acute liver damage mouse model, chronic liver damage rat model and immune liver damage mouse model were established for this study. Liver func...
Objective To study the liver protection of total celosins (CES) in different liver damage models. Method Acute liver damage mouse model, chronic liver damage rat model and immune liver damage mouse model were established for this study. Liver func...
2016, 34(3): 206-209,288.
doi: 10.3969/j.issn.1006-0111.2016.03.004
Abstract:
Objective To study the protective effects and mechanism of Asiatic Acid (AA) on traumatic brain injury. Methods The closed craniocerebral injury model made by the weight-drop method and fluid percussion brain injury model were used in the study. B...
Objective To study the protective effects and mechanism of Asiatic Acid (AA) on traumatic brain injury. Methods The closed craniocerebral injury model made by the weight-drop method and fluid percussion brain injury model were used in the study. B...
2016, 34(3): 210-214.
doi: 10.3969/j.issn.1006-0111.2016.03.005
Abstract:
Objective To investigate the role and possible mechanism of combination use of chloroquine (CQ) with either dexamethasone (DEX) or radiation on multiple myeloma (MM) cell line U266. Methods Cell viability of U266 treated with CQ alone, or CQ combi...
Objective To investigate the role and possible mechanism of combination use of chloroquine (CQ) with either dexamethasone (DEX) or radiation on multiple myeloma (MM) cell line U266. Methods Cell viability of U266 treated with CQ alone, or CQ combi...
2016, 34(3): 215-218.
doi: 10.3969/j.issn.1006-0111.2016.03.006
Abstract:
Objective To study the genotoxicity of triptolide, an important active component of Tripterygium wilfordii Hook f. Methods Ames test, in vitro chromosomal aberration test of CHO cell and in vivo micronucleus assay were performed to investigate the...
Objective To study the genotoxicity of triptolide, an important active component of Tripterygium wilfordii Hook f. Methods Ames test, in vitro chromosomal aberration test of CHO cell and in vivo micronucleus assay were performed to investigate the...
2016, 34(3): 219-222,274.
doi: 10.3969/j.issn.1006-0111.2016.03.007
Abstract:
Objective To investigate mechanism of Wentilactone A (WA) inhibition of small cell lung cancer(SCLC) cell line NCI-H1688 migration. Methods The migration and proliferation were analyzed by wounding-healing assay and MTT assay[3- (4, 5-Dimethylthia...
Objective To investigate mechanism of Wentilactone A (WA) inhibition of small cell lung cancer(SCLC) cell line NCI-H1688 migration. Methods The migration and proliferation were analyzed by wounding-healing assay and MTT assay[3- (4, 5-Dimethylthia...
2016, 34(3): 223-226,277.
doi: 10.3969/j.issn.1006-0111.2016.03.008
Abstract:
Objective To study the cell proliferative effects of fungal immunomodulatory proteins from Ganoderma spp. on 26 gastric cancer cell lines in vitro. Method 26 human gastric cancer cell lines were treated with FIPs by MTS assay. The average optical ...
Objective To study the cell proliferative effects of fungal immunomodulatory proteins from Ganoderma spp. on 26 gastric cancer cell lines in vitro. Method 26 human gastric cancer cell lines were treated with FIPs by MTS assay. The average optical ...
2016, 34(3): 227-231.
doi: 10.3969/j.issn.1006-0111.2016.03.009
Abstract:
Objective To discuss the development of ADR monitoring in Chinese medical institutions by the bibliometrics. Methods Literatures from CNKI.net, VIP and Wanfang Database were retrieved, then to compliant literatures were screened according to inclu...
Objective To discuss the development of ADR monitoring in Chinese medical institutions by the bibliometrics. Methods Literatures from CNKI.net, VIP and Wanfang Database were retrieved, then to compliant literatures were screened according to inclu...
2016, 34(3): 232-236.
doi: 10.3969/j.issn.1006-0111.2016.03.010
Abstract:
Taking Pharm.D. degree education in School of Pharmacy, University of Pittsburgh as an example, this paper introduced the American pharmacists training system, degree setting for service-oriented pharmacy students, training objective, course design, ...
Taking Pharm.D. degree education in School of Pharmacy, University of Pittsburgh as an example, this paper introduced the American pharmacists training system, degree setting for service-oriented pharmacy students, training objective, course design, ...
2016, 34(3): 237-240,248.
doi: 10.3969/j.issn.1006-0111.2016.03.011
Abstract:
Objective To evaluate therapeutic effects of Sini decoction (SND) on hypothyroidism based on serum metabonomics method. Methods Twenty-four rats were randomly divided into three groups including sham group, surgery-induced hypothyroid model group ...
Objective To evaluate therapeutic effects of Sini decoction (SND) on hypothyroidism based on serum metabonomics method. Methods Twenty-four rats were randomly divided into three groups including sham group, surgery-induced hypothyroid model group ...
2016, 34(3): 241-244,270.
doi: 10.3969/j.issn.1006-0111.2016.03.012
Abstract:
Objective Our aim is to assess the performance of warfarin pharmacogenetic algorithms in patients post mechanical cardiac valve replacement under low dose warfarin anticoagulation. Methods Based on the specified standard, from January 2012 to Octo...
Objective Our aim is to assess the performance of warfarin pharmacogenetic algorithms in patients post mechanical cardiac valve replacement under low dose warfarin anticoagulation. Methods Based on the specified standard, from January 2012 to Octo...
2016, 34(3): 245-248.
doi: 10.3969/j.issn.1006-0111.2016.03.013
Abstract:
Objective To develop the methods for identification and determination of scutellarin in compound Granule Tetrandra. Methods A TLC method was used to identify quality for scutellarin, and a HPLC method was used to determine the content of scutellar...
Objective To develop the methods for identification and determination of scutellarin in compound Granule Tetrandra. Methods A TLC method was used to identify quality for scutellarin, and a HPLC method was used to determine the content of scutellar...
2016, 34(3): 249-251,254.
doi: 10.3969/j.issn.1006-0111.2016.03.014
Abstract:
Objective To establish the HPLC fingerprint of Ginseng Radix et Rhizoma Rubra for its quality control. Methods Sharpsil-T C18 column(4.6 mm×250 mm, 5 μm)was used with acetonitrile-water in gradient elution mode. The flow rate was 1.0 ml/min, the c...
Objective To establish the HPLC fingerprint of Ginseng Radix et Rhizoma Rubra for its quality control. Methods Sharpsil-T C18 column(4.6 mm×250 mm, 5 μm)was used with acetonitrile-water in gradient elution mode. The flow rate was 1.0 ml/min, the c...
2016, 34(3): 252-254.
doi: 10.3969/j.issn.1006-0111.2016.03.015
Abstract:
Objective To modify the purified water analysis methods in the Chinese Pharmacopoeia (Vol.Ⅱ, Edition 2010), and mainly focus on the pH value determination, analysis of nitrate and nitrite, and the inspection of microorganism. Methods The usage of ...
Objective To modify the purified water analysis methods in the Chinese Pharmacopoeia (Vol.Ⅱ, Edition 2010), and mainly focus on the pH value determination, analysis of nitrate and nitrite, and the inspection of microorganism. Methods The usage of ...
2016, 34(3): 255-257.
doi: 10.3969/j.issn.1006-0111.2016.03.016
Abstract:
Objective To establish a determination method for valprate in serum. Methods Serum sample was acidified by sulfuric acid and extracted with ethyl ether, cyclohexanecarboxylic acid was selected as an internal standard, α-bromoacetophenone as deriva...
Objective To establish a determination method for valprate in serum. Methods Serum sample was acidified by sulfuric acid and extracted with ethyl ether, cyclohexanecarboxylic acid was selected as an internal standard, α-bromoacetophenone as deriva...
2016, 34(3): 258-260,266.
doi: 10.3969/j.issn.1006-0111.2016.03.017
Abstract:
Objective To improve the standard of the quality control of compound chlorhexidine acetate ointment. Methods TLC was used to control the quality of menthol crystal and camphor. A method to determine chlorhexidine acetate and cocaine hydrochloride ...
Objective To improve the standard of the quality control of compound chlorhexidine acetate ointment. Methods TLC was used to control the quality of menthol crystal and camphor. A method to determine chlorhexidine acetate and cocaine hydrochloride ...
2016, 34(3): 261-266.
doi: 10.3969/j.issn.1006-0111.2016.03.018
Abstract:
Objective To investigate whether decreasing affinity of CAR-T cells can increase their therapeutic outcome or not. Methods Moderate affinity La-G3HER2-CAR and high affinity Ha-G3HER2-CAR were constructed, and electroporated to modify T cells. West...
Objective To investigate whether decreasing affinity of CAR-T cells can increase their therapeutic outcome or not. Methods Moderate affinity La-G3HER2-CAR and high affinity Ha-G3HER2-CAR were constructed, and electroporated to modify T cells. West...
2016, 34(3): 267-270.
doi: 10.3969/j.issn.1006-0111.2016.03.019
Abstract:
Objective To study the efficacies and adverse reactions of urapidil and nicardipine in the treatment of the chronic renal failure patients with hypertensive emergencies. Methods 59 chronic renal failure patients with hypertensive emergencies were ...
Objective To study the efficacies and adverse reactions of urapidil and nicardipine in the treatment of the chronic renal failure patients with hypertensive emergencies. Methods 59 chronic renal failure patients with hypertensive emergencies were ...
2016, 34(3): 271-274.
doi: 10.3969/j.issn.1006-0111.2016.03.020
Abstract:
Objective To investigate anti-ulcerative drug (AUD) utility in patients undergoing thyroid operation against stress ulcer (SU) during perioperative period. Methods A total of 393 patients undergoing arthroscopic operation during Jan. to Dec. 2013 ...
Objective To investigate anti-ulcerative drug (AUD) utility in patients undergoing thyroid operation against stress ulcer (SU) during perioperative period. Methods A total of 393 patients undergoing arthroscopic operation during Jan. to Dec. 2013 ...
2016, 34(3): 275-277.
doi: 10.3969/j.issn.1006-0111.2016.03.021
Abstract:
Objective To observe the clinical efficacy and safety of Xuanfeizhisou mixture in the treatment of infantile bronchitis. Methods 120 cases of children with infantile bronchitis were randomly divided into observation group of 58 cases and control g...
Objective To observe the clinical efficacy and safety of Xuanfeizhisou mixture in the treatment of infantile bronchitis. Methods 120 cases of children with infantile bronchitis were randomly divided into observation group of 58 cases and control g...
2016, 34(3): 278-282.
doi: 10.3969/j.issn.1006-0111.2016.03.022
Abstract:
Objective To provide a reference for optimizing pharmacy human resources allocation in military hospitals in a region. Methods Data of pharmacy human resources of 15 military hospitals in a region were collected from 2 pharmacy resources investiga...
Objective To provide a reference for optimizing pharmacy human resources allocation in military hospitals in a region. Methods Data of pharmacy human resources of 15 military hospitals in a region were collected from 2 pharmacy resources investiga...
2016, 34(3): 283-288.
doi: 10.3969/j.issn.1006-0111.2016.03.023
Abstract:
Objective To assess differences between the medicine treatment level of military inpatients in military hospital in 2009 and 2011, provide references for reasonable adjustments of health policy in future. Methods Medicine treatment data from acute...
Objective To assess differences between the medicine treatment level of military inpatients in military hospital in 2009 and 2011, provide references for reasonable adjustments of health policy in future. Methods Medicine treatment data from acute...