2016 Vol. 34, No. 4
Display Method:
2016, 34(4): 289-291,296.
doi: 10.3969/j.issn.1006-0111.2016.04.001
Abstract:
Erzhiwan includes two components of Chinese herbal medicines-Ligustri Lucidi Fructus and Herba Ecliptae. Ligustri Lucidi Fructus, Herba Ecliptae and their formulation have various hepatoprotective effects. There are many active ingredients in the for...
Erzhiwan includes two components of Chinese herbal medicines-Ligustri Lucidi Fructus and Herba Ecliptae. Ligustri Lucidi Fructus, Herba Ecliptae and their formulation have various hepatoprotective effects. There are many active ingredients in the for...
2016, 34(4): 292-296.
doi: 10.3969/j.issn.1006-0111.2016.04.002
Abstract:
Orphan nuclear receptor NR4A1 from the NR4A subfamily is one of the transcriptional factors that have not identified specific ligands. Previous studies have found that NR4A1 could regulate cell proliferation, apoptosis, differentiation and stress res...
Orphan nuclear receptor NR4A1 from the NR4A subfamily is one of the transcriptional factors that have not identified specific ligands. Previous studies have found that NR4A1 could regulate cell proliferation, apoptosis, differentiation and stress res...
2016, 34(4): 297-300,376.
doi: 10.3969/j.issn.1006-0111.2016.04.003
Abstract:
Intracerebral hemorrhage (ICH) refers to bleeding within the brain parenchyma due to the rupture of blood vessels, and is a highly lethal stroke subtype, accounting for nearly 10%-15% of all strokes. The morbidity and mortality of ICH are very high a...
Intracerebral hemorrhage (ICH) refers to bleeding within the brain parenchyma due to the rupture of blood vessels, and is a highly lethal stroke subtype, accounting for nearly 10%-15% of all strokes. The morbidity and mortality of ICH are very high a...
2016, 34(4): 301-304,333.
doi: 10.3969/j.issn.1006-0111.2016.04.004
Abstract:
Detection of biomarkers benefited many advanced non-small cell lung cancer (NSCLC) patients. In recent years, epidermal growth factor (EGFR) tyrosine kinase inhibitors (TKIs) represented by Gefitinib, Erlotinib, Afatinib and anaplastic lymphoma kinas...
Detection of biomarkers benefited many advanced non-small cell lung cancer (NSCLC) patients. In recent years, epidermal growth factor (EGFR) tyrosine kinase inhibitors (TKIs) represented by Gefitinib, Erlotinib, Afatinib and anaplastic lymphoma kinas...
2016, 34(4): 305-308,321.
doi: 10.3969/j.issn.1006-0111.2016.04.005
Abstract:
This review described the post abdominal surgery anti-adhesive products and technology used domestically and internationally. The methods of administration, evaluation of pharmacodynamics and safety, and mechanism of adhesion were also summarized in ...
This review described the post abdominal surgery anti-adhesive products and technology used domestically and internationally. The methods of administration, evaluation of pharmacodynamics and safety, and mechanism of adhesion were also summarized in ...
2016, 34(4): 309-312.
doi: 10.3969/j.issn.1006-0111.2016.04.006
Abstract:
Neuropathic pain (NPP) is a chronic pain that caused by a series of infection and nerve damage events. It has high incidence, complex etiology and seriously affects patients' life quality. Although clinic trials gradually increased, the treatment of ...
Neuropathic pain (NPP) is a chronic pain that caused by a series of infection and nerve damage events. It has high incidence, complex etiology and seriously affects patients' life quality. Although clinic trials gradually increased, the treatment of ...
2016, 34(4): 313-317,353.
doi: 10.3969/j.issn.1006-0111.2016.04.007
Abstract:
Objective To establish an HPLC method for the quantitation of nine ginsenosides (Rc,Rb1,Rb2,Re,Rd,Rg1,Rg2,Rg3 and Rh2) in Panax ginseng samples. Methods An HPLC method was developed to determine the quantities of the nine ginsenosides. The determi...
Objective To establish an HPLC method for the quantitation of nine ginsenosides (Rc,Rb1,Rb2,Re,Rd,Rg1,Rg2,Rg3 and Rh2) in Panax ginseng samples. Methods An HPLC method was developed to determine the quantities of the nine ginsenosides. The determi...
2016, 34(4): 318-319,371.
doi: 10.3969/j.issn.1006-0111.2016.04.008
Abstract:
Objective To study the influence of eleutheroside E(ELE)on the learning and memory abilities of mice induced by para-chlorophenylalanine (PCPA) and on hippocampus' monoamine neurotransmitters of serotonin(5-HT),5-hydroxindole acetic acid (5-HIAA), d...
Objective To study the influence of eleutheroside E(ELE)on the learning and memory abilities of mice induced by para-chlorophenylalanine (PCPA) and on hippocampus' monoamine neurotransmitters of serotonin(5-HT),5-hydroxindole acetic acid (5-HIAA), d...
2016, 34(4): 320-323,342.
doi: 10.3969/j.issn.1006-0111.2016.04.009
Abstract:
Objective To prepare sorafenib (SFN)/mesoporous silica solid dispersion (SD) and investigate characteristics in vitro and in vivo. Methods The SD was prepared by solvent evaporation method; the optimal ratio of SFN to mesoporous silica was determi...
Objective To prepare sorafenib (SFN)/mesoporous silica solid dispersion (SD) and investigate characteristics in vitro and in vivo. Methods The SD was prepared by solvent evaporation method; the optimal ratio of SFN to mesoporous silica was determi...
2016, 34(4): 324-326,347.
doi: 10.3969/j.issn.1006-0111.2016.04.010
Abstract:
Objective Study on skin irritation and allergenicity of indomethacin emulsion, in order to provide theoretical basis for clinical safe medication. Methods New Zealand white rabbits were used to test skin irritation, given 0.5g test substance for 1...
Objective Study on skin irritation and allergenicity of indomethacin emulsion, in order to provide theoretical basis for clinical safe medication. Methods New Zealand white rabbits were used to test skin irritation, given 0.5g test substance for 1...
2016, 34(4): 327-329.
doi: 10.3969/j.issn.1006-0111.2016.04.011
Abstract:
Objective To evaluate the physical dependence of total Ervatamia yunnansis alkaloid. Methods The physical dependence of total Ervatamia yunnansis alkaloid was observed by jump test in mice and spontaneous withdrawal test in rats. Results In the ...
Objective To evaluate the physical dependence of total Ervatamia yunnansis alkaloid. Methods The physical dependence of total Ervatamia yunnansis alkaloid was observed by jump test in mice and spontaneous withdrawal test in rats. Results In the ...
2016, 34(4): 330-333.
doi: 10.3969/j.issn.1006-0111.2016.04.012
Abstract:
Objective The research is about optimization of preparation procedure of self-microemulsifying dropping pills of paclitaxel (PTX-SM-DP). The drug release in vitro of PTX-SM-DP was investigated. Methods The ratio of SMEDDS and bases, dropping dista...
Objective The research is about optimization of preparation procedure of self-microemulsifying dropping pills of paclitaxel (PTX-SM-DP). The drug release in vitro of PTX-SM-DP was investigated. Methods The ratio of SMEDDS and bases, dropping dista...
2016, 34(4): 334-337.
doi: 10.3969/j.issn.1006-0111.2016.04.013
Abstract:
Objective To design and synthesis novel triazole antifungal derivatives with dithiocarbamates side chain and study the antifungal activities. Methods Nine title compounds were synthesized and characterized by 1H NMR, MS spectra. The in vitro antif...
Objective To design and synthesis novel triazole antifungal derivatives with dithiocarbamates side chain and study the antifungal activities. Methods Nine title compounds were synthesized and characterized by 1H NMR, MS spectra. The in vitro antif...
2016, 34(4): 338-342.
doi: 10.3969/j.issn.1006-0111.2016.04.014
Abstract:
Objective To establish quality control of Xinnaoling granules. Methods Thin layer chromatography (TLC) methods were used to identify Rhizoma Corydalis, Radix Angelicae dahuricae, Cortex Magnoliae officinalis, Radix Glycyrrhizae, Rhizoma Ligusticum...
Objective To establish quality control of Xinnaoling granules. Methods Thin layer chromatography (TLC) methods were used to identify Rhizoma Corydalis, Radix Angelicae dahuricae, Cortex Magnoliae officinalis, Radix Glycyrrhizae, Rhizoma Ligusticum...
2016, 34(4): 343-347.
doi: 10.3969/j.issn.1006-0111.2016.04.015
Abstract:
Objective To improve the quality standard of Minuo Hair Solution and to ensure product quality. Methods Thin layer chromatography (TLC) and UV-visible spectroscopy (UV-Vis) method was used for the qualitative identification of Angelica sinensis, P...
Objective To improve the quality standard of Minuo Hair Solution and to ensure product quality. Methods Thin layer chromatography (TLC) and UV-visible spectroscopy (UV-Vis) method was used for the qualitative identification of Angelica sinensis, P...
2016, 34(4): 348-350,356.
doi: 10.3969/j.issn.1006-0111.2016.04.016
Abstract:
Objective To study the rat pulmonary irritant of aerosol inhaled Tanreqing and Reduning injection. Methods Rats were devided into two groups for each medicine (low concentration group and high concentration group), nebulized drug administration fo...
Objective To study the rat pulmonary irritant of aerosol inhaled Tanreqing and Reduning injection. Methods Rats were devided into two groups for each medicine (low concentration group and high concentration group), nebulized drug administration fo...
2016, 34(4): 351-353.
doi: 10.3969/j.issn.1006-0111.2016.04.017
Abstract:
Objective To develop a new high performance liquid chromatography (HPLC) coupled with Evaporative Light Scattering Detector (ELSD) method for simultaneous determination of two indicative components (peimine and peiminine) in Xiaoer Baotaikang granul...
Objective To develop a new high performance liquid chromatography (HPLC) coupled with Evaporative Light Scattering Detector (ELSD) method for simultaneous determination of two indicative components (peimine and peiminine) in Xiaoer Baotaikang granul...
2016, 34(4): 354-356.
doi: 10.3969/j.issn.1006-0111.2016.04.018
Abstract:
Objective To investigate the mechanism of anti-epileptic effect of the curcumin. Methods The SD rats were injected intraperitoneally with pentylenetetrazol kindling 25.0 mg/kg to induce a rat epilepsy model. All of the treatments were performed on...
Objective To investigate the mechanism of anti-epileptic effect of the curcumin. Methods The SD rats were injected intraperitoneally with pentylenetetrazol kindling 25.0 mg/kg to induce a rat epilepsy model. All of the treatments were performed on...
2016, 34(4): 357-358,384.
doi: 10.3969/j.issn.1006-0111.2016.04.019
Abstract:
Objective To investigate the stability of torasemide injection and predict its expiration date in room temperatue. Methods The contents of torasemide were determined by HPLC. The expiration date was predicted by classical constant-temperature expe...
Objective To investigate the stability of torasemide injection and predict its expiration date in room temperatue. Methods The contents of torasemide were determined by HPLC. The expiration date was predicted by classical constant-temperature expe...
Effect of preoperative compound matrine injection combined with chemotherapy on lung cancer patients
2016, 34(4): 359-362.
doi: 10.3969/j.issn.1006-0111.2016.04.020
Abstract:
Objective To study the effect of preoperative compound matrine injection combined with chemotherapy on serum index apoptotic molecules and signaling molecules expression in tumor tissues of lung cancer patients. Methods Patients with diagnosed lun...
Objective To study the effect of preoperative compound matrine injection combined with chemotherapy on serum index apoptotic molecules and signaling molecules expression in tumor tissues of lung cancer patients. Methods Patients with diagnosed lun...
2016, 34(4): 363-365.
doi: 10.3969/j.issn.1006-0111.2016.04.021
Abstract:
Objective To discuss the pharmaceutical care experience of the clinical pharmacist in anti-infectious treatment of one patient with febrile neutropenia. Methods The clinical pharmacists participated in the treatment of the patient with febrile neu...
Objective To discuss the pharmaceutical care experience of the clinical pharmacist in anti-infectious treatment of one patient with febrile neutropenia. Methods The clinical pharmacists participated in the treatment of the patient with febrile neu...
2016, 34(4): 366-371.
doi: 10.3969/j.issn.1006-0111.2016.04.022
Abstract:
Objective To discuss dendritic cell-cytokine-induced killer (DC-CIK) cell therapy effects and clinical outcomes in patients with colorectal cancer in order to have better clinical treatment. Methods A retrospective analysis of the data of 66 patie...
Objective To discuss dendritic cell-cytokine-induced killer (DC-CIK) cell therapy effects and clinical outcomes in patients with colorectal cancer in order to have better clinical treatment. Methods A retrospective analysis of the data of 66 patie...
2016, 34(4): 372-376.
doi: 10.3969/j.issn.1006-0111.2016.04.023
Abstract:
The great potential of cell therapy based on chimeric antigen receptor (CAR) has been demonstrated in the treatment of malignant tumors through 25 years of research.A large number of experimental and clinical data have been reported in recent years.T...
The great potential of cell therapy based on chimeric antigen receptor (CAR) has been demonstrated in the treatment of malignant tumors through 25 years of research.A large number of experimental and clinical data have been reported in recent years.T...
2016, 34(4): 377-379.
doi: 10.3969/j.issn.1006-0111.2016.04.024
Abstract:
Objective To analyze the use of hypoglycemic agents of diabetic adult patients who were managed in the Community Health Service Center of Huazhong University of Science and Technology in Wuhan. Methods By analyzing of follow-up record of 647 adult...
Objective To analyze the use of hypoglycemic agents of diabetic adult patients who were managed in the Community Health Service Center of Huazhong University of Science and Technology in Wuhan. Methods By analyzing of follow-up record of 647 adult...
2016, 34(4): 380-384.
doi: 10.3969/j.issn.1006-0111.2016.04.025
Abstract:
Objective To evaluate the effecacy of Bifidobacterium viable triple capsule on anti-Helicobacter pylori (Hp) treatment and its adverse reactions during eradication therapy. Methods Trials on the effect of Bifidobacterium viable triple capsule on H...
Objective To evaluate the effecacy of Bifidobacterium viable triple capsule on anti-Helicobacter pylori (Hp) treatment and its adverse reactions during eradication therapy. Methods Trials on the effect of Bifidobacterium viable triple capsule on H...
Contribution System
Author Login
Review Login
Editor Login
Reader Login
News