2009 Vol. 27, No. 4
Display Method:
2009, 27(4): 254-257.
Abstract:
Objective :To prepare human serum albumin(HSA) injectable gel.To optimize the formulations of injectable gel by a central composite design/response surface methodology. Methods : Injectable gel loaded HSA were prepared with poly(lactic-co-glycolic ac...
Objective :To prepare human serum albumin(HSA) injectable gel.To optimize the formulations of injectable gel by a central composite design/response surface methodology. Methods : Injectable gel loaded HSA were prepared with poly(lactic-co-glycolic ac...
2009, 27(4): 258-260,320.
Abstract:
Objective :To develop a LC-MS-MS assay for the determination of ibuprofen in human serum and to investigate the pharmacokinetics and bioequivalence of two preparation in Chinese healthy volunteers. Methods : A single per rectum dose of 50 mg ibuprofe...
Objective :To develop a LC-MS-MS assay for the determination of ibuprofen in human serum and to investigate the pharmacokinetics and bioequivalence of two preparation in Chinese healthy volunteers. Methods : A single per rectum dose of 50 mg ibuprofe...
2009, 27(4): 261-263.
Abstract:
Objective :To investigate the effects of Zhixiao Tongmaining granules on diabetic nephropathy. Methods : The blood stasis of rats were detected by blood rheometer to investigate the effects of activating blood circulation to dissipate blood stasis of...
Objective :To investigate the effects of Zhixiao Tongmaining granules on diabetic nephropathy. Methods : The blood stasis of rats were detected by blood rheometer to investigate the effects of activating blood circulation to dissipate blood stasis of...
2009, 27(4): 264-265,269.
Abstract:
Objective :To study the effect and revelation of Joint Medical Asset Repository on enhancing the effectiveness of U.S.military medical supply system. Methods : Analyzing relevant literature and reports on the development and application of the U.S.ar...
Objective :To study the effect and revelation of Joint Medical Asset Repository on enhancing the effectiveness of U.S.military medical supply system. Methods : Analyzing relevant literature and reports on the development and application of the U.S.ar...
2009, 27(4): 266-269.
Abstract:
Objective :Design and synthesis of novel triazole antifungal derivatives based on the structure of fluconazole. Methods : A cyclohexyl group introduced and a series title compounds synthesized All of them were confirmed by MS,1H-NMR,et al.The antifun...
Objective :Design and synthesis of novel triazole antifungal derivatives based on the structure of fluconazole. Methods : A cyclohexyl group introduced and a series title compounds synthesized All of them were confirmed by MS,1H-NMR,et al.The antifun...
2009, 27(4): 270-273,278.
Abstract:
Objective :To analyze chemical constituents of Sini decoction by rapid-resolution liquid chromatography-time of flight mass spectrometry(RRLC-TOF/MS). Methods : IThe separation was performed on a SHISEIDO CAPCELL PAK C18 reverse phase column(50 mm×2....
Objective :To analyze chemical constituents of Sini decoction by rapid-resolution liquid chromatography-time of flight mass spectrometry(RRLC-TOF/MS). Methods : IThe separation was performed on a SHISEIDO CAPCELL PAK C18 reverse phase column(50 mm×2....
2009, 27(4): 274-275,304.
Abstract:
Objective : To study the effect of ZTC1+1 natural clarifying agents on the purification of Qingkailing oral liquid. Methods :The nitrogen content of Qingkailing oral liquid was taken as index.The optimum conditions were obtained by orthogonal experim...
Objective : To study the effect of ZTC1+1 natural clarifying agents on the purification of Qingkailing oral liquid. Methods :The nitrogen content of Qingkailing oral liquid was taken as index.The optimum conditions were obtained by orthogonal experim...
2009, 27(4): 276-278.
Abstract:
Objective : To study the pharmacokinetics of self-emulsifying drug delivery systems of adefovir dipivoxil in rats. Methods : Six SD rats were randomly divided into two groups for oral administration of the self-emulsifying adefovir dipivoxil and adef...
Objective : To study the pharmacokinetics of self-emulsifying drug delivery systems of adefovir dipivoxil in rats. Methods : Six SD rats were randomly divided into two groups for oral administration of the self-emulsifying adefovir dipivoxil and adef...
2009, 27(4): 279-281.
Abstract:
Objective :To investigate the physico-chemical properties of scopolamine hydrobromide micromulsion and its transdermal delivery effect in vitro. Methods : The O/W microemulsion was prepared with the system contained of Cremophor RH-40-ethanol-Labrafi...
Objective :To investigate the physico-chemical properties of scopolamine hydrobromide micromulsion and its transdermal delivery effect in vitro. Methods : The O/W microemulsion was prepared with the system contained of Cremophor RH-40-ethanol-Labrafi...
2009, 27(4): 282-283,293.
Abstract:
Objective :To establish a carbazole method for the simultaneous determination of sodium hyaluronate(SH) and chondroitin sulfate(CS). Methods : By regulating acidity or alkalinity and ionic strength with sodium acetate,CS was selectively precipitated ...
Objective :To establish a carbazole method for the simultaneous determination of sodium hyaluronate(SH) and chondroitin sulfate(CS). Methods : By regulating acidity or alkalinity and ionic strength with sodium acetate,CS was selectively precipitated ...
2009, 27(4): 284-285,288.
Abstract:
Objective : To establish a HPLC method for simultaneous determination of five flavone constituents in Epimedium Brevicornum. Methods :The determination was performed on Diamonsil-C18 column(4.6mm×250mm,5μm,Dikma).The mobile phase was consisted of ace...
Objective : To establish a HPLC method for simultaneous determination of five flavone constituents in Epimedium Brevicornum. Methods :The determination was performed on Diamonsil-C18 column(4.6mm×250mm,5μm,Dikma).The mobile phase was consisted of ace...
2009, 27(4): 286-288.
Abstract:
Objective :To establish a method for determination of hyperoside in Shanzha Maiqu granule. Methods :HPLC was adopted with Agilent ZORBAX SB-C18 column(4.6 mm×250 mm,5 μm),methanol-tetrahydrofuran-0.5% H3PO4(0.917.681.5) as mobile phase at flow rate...
Objective :To establish a method for determination of hyperoside in Shanzha Maiqu granule. Methods :HPLC was adopted with Agilent ZORBAX SB-C18 column(4.6 mm×250 mm,5 μm),methanol-tetrahydrofuran-0.5% H3PO4(0.917.681.5) as mobile phase at flow rate...
2009, 27(4): 289-290,293.
Abstract:
Objective :To determine the content of luteolin in three kinds of Chrysanthemum morifolium that are often seen in market by HPLC. Methods : The luteolin was quantified by reverse-HPLC on Diamosil C18 column(250 mm×4.6 mm,5 μm)using methanol-water(cha...
Objective :To determine the content of luteolin in three kinds of Chrysanthemum morifolium that are often seen in market by HPLC. Methods : The luteolin was quantified by reverse-HPLC on Diamosil C18 column(250 mm×4.6 mm,5 μm)using methanol-water(cha...
2009, 27(4): 291-293.
Abstract:
Objective : To determine quantitatively ginsenoside Re in total ginsenoside from stalk and leaf of Panax ginseng,and to provide experimental evident for total ginsenoside quality control of Panax ginseng. Methods :The method was developed with the co...
Objective : To determine quantitatively ginsenoside Re in total ginsenoside from stalk and leaf of Panax ginseng,and to provide experimental evident for total ginsenoside quality control of Panax ginseng. Methods :The method was developed with the co...
2009, 27(4): 294-296.
Abstract:
Objective :The study was aimed at the quality management which the department of drug R&D wanted to build. Methods : The method of project breakdown was used.The key-point emphasis and the target in different stage were put forward according to the《D...
Objective :The study was aimed at the quality management which the department of drug R&D wanted to build. Methods : The method of project breakdown was used.The key-point emphasis and the target in different stage were put forward according to the《D...
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