2009 Vol. 27, No. 5
Display Method:
2009, 27(5): 323-333,361.
Abstract:
Objective :To establish an inhibition research method of three commonly-used anti-tumor drugs against HepG2 cell line. Methods : The determination was performed on a 96-well plate.The drugs were administrated in a series of concentrations,and each co...
Objective :To establish an inhibition research method of three commonly-used anti-tumor drugs against HepG2 cell line. Methods : The determination was performed on a 96-well plate.The drugs were administrated in a series of concentrations,and each co...
2009, 27(5): 324-327,392.
Abstract:
Objective :Design and synthesis of novel triazole antifungal derivatives based on the structure of fluconazole. Methods : A isopropyl and substituted amino group were introduced and a series of title compounds were synthesized.All of them were confir...
Objective :Design and synthesis of novel triazole antifungal derivatives based on the structure of fluconazole. Methods : A isopropyl and substituted amino group were introduced and a series of title compounds were synthesized.All of them were confir...
2009, 27(5): 328-331.
Abstract:
Objective :To study on synthesis and antiviral activities of 5-substituted pyrimidine acyclic nucleoside phosphonate compounds on HBV. Methods : Starting with substituted pyrimidine,we synthesized 8 firstly reported compounds 1a～1h.Preliminary pharma...
Objective :To study on synthesis and antiviral activities of 5-substituted pyrimidine acyclic nucleoside phosphonate compounds on HBV. Methods : Starting with substituted pyrimidine,we synthesized 8 firstly reported compounds 1a～1h.Preliminary pharma...
2009, 27(5): 334-336,352.
Abstract:
Objective :To investigate the therapeutical effects of Danhong for injection on myocardial infarction model induced by coronary artery ligation in dogs. Methods : The models of myocardial infarction were produced by ligation of the left anterior desc...
Objective :To investigate the therapeutical effects of Danhong for injection on myocardial infarction model induced by coronary artery ligation in dogs. Methods : The models of myocardial infarction were produced by ligation of the left anterior desc...
2009, 27(5): 337-339,372.
Abstract:
Objective :To observe local necrosis of rat livers resulted from glycolic acid injection and compare necrosis effects resulted from glycolic acid injection and ethanol injection. Methods :After injections of a series of concentrations of glycolic aci...
Objective :To observe local necrosis of rat livers resulted from glycolic acid injection and compare necrosis effects resulted from glycolic acid injection and ethanol injection. Methods :After injections of a series of concentrations of glycolic aci...
2009, 27(5): 340-344.
Abstract:
Objective : To study the synergistic protective effect and mechanism of extracts from Fructus Schisandrae chinensis(EFS) with astragalus polysaccharides(APS) on paracetamol-induced liver injury in mice. Methods :Mice liver injury was induced by perit...
Objective : To study the synergistic protective effect and mechanism of extracts from Fructus Schisandrae chinensis(EFS) with astragalus polysaccharides(APS) on paracetamol-induced liver injury in mice. Methods :Mice liver injury was induced by perit...
2009, 27(5): 345-348,369.
Abstract:
Objective : To optimize the formulation of oridonin-loaded PLA nanoparticles with modified spontaneous emulsification solvent diffusion method. Methods :Applying central composite design and response surface method,choose the concentration of drug in...
Objective : To optimize the formulation of oridonin-loaded PLA nanoparticles with modified spontaneous emulsification solvent diffusion method. Methods :Applying central composite design and response surface method,choose the concentration of drug in...
2009, 27(5): 349-352.
Abstract:
Objective : To reveal the processing principleg of preparation of Radix Aconiti by electrospray ionization trap mass spectrometry. Methods : The three reference standars were made MSn analysis and elucidating the fragmentation pathways.The rapid anal...
Objective : To reveal the processing principleg of preparation of Radix Aconiti by electrospray ionization trap mass spectrometry. Methods : The three reference standars were made MSn analysis and elucidating the fragmentation pathways.The rapid anal...
2009, 27(5): 353-356.
Abstract:
Objective :The effects of the 20 Chinese Patent Medicines on the catalytic activities of five main drug metabolism enzymes of human liver microsome,CYP1A2,CYP2C9,CYP2C19,CYP2D6 and CYP 3A4,were assessed. Methods : Human liver microsome incubation exp...
Objective :The effects of the 20 Chinese Patent Medicines on the catalytic activities of five main drug metabolism enzymes of human liver microsome,CYP1A2,CYP2C9,CYP2C19,CYP2D6 and CYP 3A4,were assessed. Methods : Human liver microsome incubation exp...
2009, 27(5): 357-358.
Abstract:
Objective :To evaluate the efficacy and safety of cefazolin sodium pentahydrate in the treatment of acute stage of COPD. Methods : A randomized,controlled clinical trail was carried.A total of 65 patients of COPD were randomly divided into three grou...
Objective :To evaluate the efficacy and safety of cefazolin sodium pentahydrate in the treatment of acute stage of COPD. Methods : A randomized,controlled clinical trail was carried.A total of 65 patients of COPD were randomly divided into three grou...
2009, 27(5): 359-361.
Abstract:
Objective :To establish a capillary electrophoresis(CE) method for determining the illegally added ingredient diclofenac potassium in TCM,Shuguning tablet. Methods : CE was used for the separation by using the uncoaded capillary(75 μm×50 cm) and buff...
Objective :To establish a capillary electrophoresis(CE) method for determining the illegally added ingredient diclofenac potassium in TCM,Shuguning tablet. Methods : CE was used for the separation by using the uncoaded capillary(75 μm×50 cm) and buff...
2009, 27(5): 362-364.
Abstract:
Objective :To analyze the chemical constituents of essential oil extracted from fresh leaves of Artemisia argyi cultivated in Shanghai,so that to provide valuable information for use of fresh leaves of Artemisia argyi. Methods : Hydrodistillation was...
Objective :To analyze the chemical constituents of essential oil extracted from fresh leaves of Artemisia argyi cultivated in Shanghai,so that to provide valuable information for use of fresh leaves of Artemisia argyi. Methods : Hydrodistillation was...
2009, 27(5): 365-366,387.
Abstract:
Objective :To establish a method for determination of five residual solvents in gatifloxacin. Methods : The residual organic solvents which are ethanol,acetonitrile,dichloromethane,ethyl acetate,toluene were quantitatively determined by headspace GC ...
Objective :To establish a method for determination of five residual solvents in gatifloxacin. Methods : The residual organic solvents which are ethanol,acetonitrile,dichloromethane,ethyl acetate,toluene were quantitatively determined by headspace GC ...
2009, 27(5): 367-369.
Abstract:
Objective :To prepare cetirizine hydrochloride gel and study its skin penetration in vitro. Methods : Cetirizine gel was prepared with carbopol 940 as base material.Using Franz diffusion cell and excised rat skin in vitro as transdermal barrier.The c...
Objective :To prepare cetirizine hydrochloride gel and study its skin penetration in vitro. Methods : Cetirizine gel was prepared with carbopol 940 as base material.Using Franz diffusion cell and excised rat skin in vitro as transdermal barrier.The c...
2009, 27(5): 370-372.
Abstract:
Objective :To assess the stability of electrolyzed oxidizing water and its disinfection effect on hand and on article surface. Methods : Electrolyzed oxidizing water was stored for 90 days under the room temperature and its effective chlorine content...
Objective :To assess the stability of electrolyzed oxidizing water and its disinfection effect on hand and on article surface. Methods : Electrolyzed oxidizing water was stored for 90 days under the room temperature and its effective chlorine content...
2009, 27(5): 373-374,389.
Abstract:
Objective :To discuss ideas and practices of joint applying 2D barcode and RFID technology in medical logistics tracking system. Methods :Analysis the technology features of 2D barcode and RFID technology,with the features of medical logistics indust...
Objective :To discuss ideas and practices of joint applying 2D barcode and RFID technology in medical logistics tracking system. Methods :Analysis the technology features of 2D barcode and RFID technology,with the features of medical logistics indust...
2009, 27(5): 375-377.
Abstract:
Biomedical industry is a new emerging high-tech industry,coupled with risk factors,and more and more attentions have been taken on the safety of biomedicine.After the appearance of some safety issues,both the pharmaceutical industry and the public ha...
Biomedical industry is a new emerging high-tech industry,coupled with risk factors,and more and more attentions have been taken on the safety of biomedicine.After the appearance of some safety issues,both the pharmaceutical industry and the public ha...
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