紫苏叶挥发油成分的生物合成、含量测定及生物活性研究进展

李惠萍; 陈璐; 张琪金; 黄宝康

doi:10.12206/j.issn.2097-2024.202412058

紫苏叶挥发油成分的生物合成、含量测定及生物活性研究进展

doi: 10.12206/j.issn.2097-2024.202412058

李惠萍^{1, 2, #,},
陈璐^{3, #,},
张琪金^{2, 4},
黄宝康^{1, 2, ,}

1.
福建中医药大学药学院, 福州350122
2.
海军军医大学药学院, 上海200433
3.
上海健康医学院附属周浦医院药学部, 上海201318
4.
西部战区总医院临床药学科, 成都610036

基金项目: 上海市浦东新区卫生系统优秀青年医学人才培养计划资助项目（PWRq2021-46）

详细信息

作者简介:
李惠萍，硕士研究生，Email: 2541009521@qq.com

陈　璐，硕士，主管药师，Email: chenlu7782@163.com

通讯作者: 黄宝康，教授，博士生导师，研究方向：中药资源品质评价与资源开发，Email: hbk@smmu.edu.cn

Research progress on biosynthesis, content determination and biological activity of volatile oil components in Perillae Folium

LI Huiping^{1, 2, #
,},
CHEN Lu^{3, #
,},
ZHANG Qijin^{2, 4},
HUANG Baokang^{1, 2
, ,}

1.
School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350100, China
2.
School of Pharmacy, Naval Medical University, Shanghai 200433, China
3.
Department of Pharmacy, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai 201318, China
4.
Department of Clinical Pharmacy, Western Theater General Hospital, Chengdu 610036, China

摘要: 紫苏为唇形科紫苏属的一年生草本植物，具有食用和药用价值，有着悠久的种植和使用历史。挥发油是紫苏叶的主要活性成分之一，紫苏醛为其特征性成分。挥发油含量测定方法多样，其含量受不同种质差异、生长期和提取方法影响。挥发油中成分主要由甲羟戊酸和莽草酸两条途径合成调控，具有抗菌、抗氧化、抗炎、抗肿瘤和抗抑郁等生物活性。紫苏挥发油的这些特性使其在食品保鲜、香料工业以及医药领域具有广泛的应用前景。随着对紫苏挥发油成分和生物合成途径的进一步研究，提高紫苏品质，明确挥发油的活性物质基础及作用机制，以便更深入地挖掘利用紫苏的药食两用价值。
- 紫苏叶 /
- 紫苏醛 /
- 生物合成 /
- 含量测定 /
- 生物活性
#共同第一作者
Abstract: Perilla is an annual herbaceous plant with edible and medicinal value belonging to the Lamiaceae family. It has a long history of cultivation and use. The volatile oil is one of its main active components in perilla leaves, and Perilla aldehyde is its characteristic component. The methods for determining the content of volatile oil are diverse and affected by genetic differences, growth period, and extraction methods. It is mainly synthesized and regulated through the mevalonic acid pathway and shikimic acid pathway, and has biological activities such as antibacterial, antioxidant, anti-inflammatory, anti-tumor, and anti-depressant. The characteristics of perilla volatile oil make it have broad application prospects in food preservation, fragrance industry, and medicine. With further research on the components and biosynthesis pathways of perilla volatile oil, it is important to improve the quality of perilla and further clarify the active substance basis and mechanism of action of volatile oil, and its medicinal and edible value will be further explored and utilized.
- Perillae Folium /
- volatile oil /
- biosynthesis /
- content determination /
- biological activity
图 1 紫苏叶挥发油中主要成分的化学结构

A.紫苏醛；B.紫苏酮

下载: 全尺寸图片幻灯片

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紫苏叶挥发油成分的生物合成、含量测定及生物活性研究进展

doi: 10.12206/j.issn.2097-2024.202412058

作者简介: 李惠萍，硕士研究生，Email: 2541009521@qq.com 陈 璐，硕士，主管药师，Email: chenlu7782@163.com

通讯作者: 黄宝康，教授，博士生导师，研究方向：中药资源品质评价与资源开发，Email: hbk@smmu.edu.cn

Research progress on biosynthesis, content determination and biological activity of volatile oil components in Perillae Folium

作者简介:
李惠萍，硕士研究生，Email: 2541009521@qq.com

陈　璐，硕士，主管药师，Email: chenlu7782@163.com