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哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状

李园园,  于锋

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文章导航 > 药学实践与服务  > 2014 >  32(6): 416-418,452
李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
引用本文: 李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
shu
LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
Citation: LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
shu

哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状

doi: 10.3969/j.issn.1006-0111.2014.06.005

  • 中国药科大学临床药学教研室, 江苏 南京 210009

Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium

  • Depamt, emt pf Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China

  • 摘要: 目的 为哌拉西林钠-他唑巴坦钠的临床合理用药提供参考。 方法 对哌拉西林钠-他唑巴坦钠的优选给药方案的药动/药效学研究、临床试验及具体实施情况进行综述。 结果 哌拉西林钠-他唑巴坦钠的优选给药方案(延长输注或持续输注)可最大化地达到药效学目标,改善临床有效性。 结论 需积极完善优化方案用于临床实践的策略。
    Abstract: Objective To offer reference to reasonable clinical use of piperacillin sodium sodium-tazobactam sodium. Methods We reviewed pharmacokinetic/ pharmacodynamic studies, clinical trails and implementation of piperacillin sodium-tazobactam sodium alternative dosing regimen in recent. Results The alternative dosing regimens, prolonged and continuous infusion, could maximise the likelihood of achieving desirable pharmacodynamic targets and improve clinical effectiveness. Conclusion It's needed to improve the strategies of alternative dosing regimens for clinical practice.
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  • 收稿日期:  2013-07-21
  • 修回日期:  2013-12-02

哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状

doi: 10.3969/j.issn.1006-0111.2014.06.005
  • 中国药科大学临床药学教研室, 江苏 南京 210009
  • 收稿日期: 2013-07-21
  • 修回日期: 2013-12-02

摘要: 目的 为哌拉西林钠-他唑巴坦钠的临床合理用药提供参考。 方法 对哌拉西林钠-他唑巴坦钠的优选给药方案的药动/药效学研究、临床试验及具体实施情况进行综述。 结果 哌拉西林钠-他唑巴坦钠的优选给药方案(延长输注或持续输注)可最大化地达到药效学目标,改善临床有效性。 结论 需积极完善优化方案用于临床实践的策略。

English Abstract

李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
引用本文: 李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
shu
LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
Citation: LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
shu

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