长春西汀葡萄糖注射液细菌内毒素检查的实验研究
Study on bactrial endotoxin inspection methods of vinpocetine and glucose injection
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摘要: 目的 建立用鲎试剂检查长春西汀葡萄糖注射液细菌内毒素的方法。方法 对用家兔法热原检查合格的长春西汀葡萄糖注射液作细菌内毒素检查的干扰试验。结果 长春西汀葡萄糖注射液对鲎试剂的细菌内毒素检查无干扰。结论 凝胶法鲎试验可用于长春西汀葡萄糖注射液的细菌内毒素检查。
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关键词:
- 长春西汀葡萄糖注射液 /
- 凝胶法 /
- 细菌内毒素 /
- 干扰试验 /
- 鲎试剂
Abstract: OBJECTIVE To establish method for monitoring bactrial endotoxin of vinpocetine and glucose injection. METHODS The interference function of vinpocetine and glucose injection to bactrial endotoxin was determined with tachyplens amebocyte lysate(TAL), which determined well by pyrogen test method. RESULTS Vinpocetine and glucose injection has not interference function on bactrial endotoxin inspection. CONCLUSION Method of gelation assay can determine bactrial endotoxin in vinpocetine and glucose injection. -
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