2019 Vol. 37, No. 6
Display Method:
2019, 37(6): 481-484.
doi: 10.3969/j.issn.1006-0111.2019.06.001
Abstract:
Malaria is a critical public health problem resulting in substantial morbidity and mortality in developing countries,especially in Africa.Quinoline,dihydrofolate reductase inhibitors and artemisinin drugs are currently the main drugs for the treatmen...
Malaria is a critical public health problem resulting in substantial morbidity and mortality in developing countries,especially in Africa.Quinoline,dihydrofolate reductase inhibitors and artemisinin drugs are currently the main drugs for the treatmen...
2019, 37(6): 485-490.
doi: 10.3969/j.issn.1006-0111.2019.06.002
Abstract:
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by joint damage and synovial inflammation.Two major classes of RA drugs,including small molecule synthetic RA drugs and macromolecular biological RA drugs (TNF inhibitors、B cell i...
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by joint damage and synovial inflammation.Two major classes of RA drugs,including small molecule synthetic RA drugs and macromolecular biological RA drugs (TNF inhibitors、B cell i...
2019, 37(6): 491-494.
doi: 10.3969/j.issn.1006-0111.2019.06.003
Abstract:
Objective To investigate the low-polarity components from the stems of Schisandra rubriflora (Franch).Rehd.et Wils. Methods Dried and grinded stems of this plant were extracted by 90% ethylalcohol,then the extraction was partitioned by petroleum et...
Objective To investigate the low-polarity components from the stems of Schisandra rubriflora (Franch).Rehd.et Wils. Methods Dried and grinded stems of this plant were extracted by 90% ethylalcohol,then the extraction was partitioned by petroleum et...
2019, 37(6): 495-497,526.
doi: 10.3969/j.issn.1006-0111.2019.06.004
Abstract:
Objective To compare the content of total flavonoids in Herba Anoectochilus and its adulterants. Methods Rutin was selected as reference substance,the total flavonoids in Herba Anoectochilus and its adulterants were determined by ultraviolet spectr...
Objective To compare the content of total flavonoids in Herba Anoectochilus and its adulterants. Methods Rutin was selected as reference substance,the total flavonoids in Herba Anoectochilus and its adulterants were determined by ultraviolet spectr...
2019, 37(6): 498-502.
doi: 10.3969/j.issn.1006-0111.2019.06.005
Abstract:
Objective To study the protective effect and explore the mechanism of monocyte locomotion inhibitor factor(MLIF) on traumatic brain injury (TBI) in rats. Methods The SD rats were randomly divided into five groups:sham operation group,model group an...
Objective To study the protective effect and explore the mechanism of monocyte locomotion inhibitor factor(MLIF) on traumatic brain injury (TBI) in rats. Methods The SD rats were randomly divided into five groups:sham operation group,model group an...
2019, 37(6): 503-507.
doi: 10.3969/j.issn.1006-0111.2019.06.006
Abstract:
Objective To establish a pharmacokinetic method for simultaneous determination the drug concentration in the skin and blood for transdermal formulations,and to study the absorption and metabolism of matrine gel in vivo. Methods A micro dialysis pro...
Objective To establish a pharmacokinetic method for simultaneous determination the drug concentration in the skin and blood for transdermal formulations,and to study the absorption and metabolism of matrine gel in vivo. Methods A micro dialysis pro...
2019, 37(6): 508-511.
doi: 10.3969/j.issn.1006-0111.2019.06.007
Abstract:
Objective To establish a HPLC method for the simultaneous determination of diphenhydramine hydrochloride,octyl methoxycinnamate and octyl salicylate in multi-effect protective cream. Methods The HPLC condition was as follows.The column was Agilent ...
Objective To establish a HPLC method for the simultaneous determination of diphenhydramine hydrochloride,octyl methoxycinnamate and octyl salicylate in multi-effect protective cream. Methods The HPLC condition was as follows.The column was Agilent ...
2019, 37(6): 512-517.
doi: 10.3969/j.issn.1006-0111.2019.06.008
Abstract:
Objective To study the prototype components and metabolites of Saposhnikoviae Radixin in rats' plasma. Methods UPLC-Q-TOF-MS method was used to identify the components and metabolites of rat plasma.The Eclipse Plus C18 column(150 mm×2.1 mm,1.8 μm,A...
Objective To study the prototype components and metabolites of Saposhnikoviae Radixin in rats' plasma. Methods UPLC-Q-TOF-MS method was used to identify the components and metabolites of rat plasma.The Eclipse Plus C18 column(150 mm×2.1 mm,1.8 μm,A...
2019, 37(6): 518-520.
doi: 10.3969/j.issn.1006-0111.2019.06.009
Abstract:
Objective To establish a method for the determination of sodium fluoride in fluoride-containing mouthwash by 19F-NMR technique. Methods The 19F-NMR technique was used to establish the relevant standard curve with trifluoroacetic acid as the interna...
Objective To establish a method for the determination of sodium fluoride in fluoride-containing mouthwash by 19F-NMR technique. Methods The 19F-NMR technique was used to establish the relevant standard curve with trifluoroacetic acid as the interna...
2019, 37(6): 521-526.
doi: 10.3969/j.issn.1006-0111.2019.06.010
Abstract:
Objective To study the preparation technology and quality of cefotiam hexetil hydrochloride tablet. Methods The disintegration time limit and dissolution of drug were taken as the main index.The original piece of reference was used to optimize the ...
Objective To study the preparation technology and quality of cefotiam hexetil hydrochloride tablet. Methods The disintegration time limit and dissolution of drug were taken as the main index.The original piece of reference was used to optimize the ...
2019, 37(6): 527-531.
doi: 10.3969/j.issn.1006-0111.2019.06.011
Abstract:
Objective To establish microbial limit test methods for 6 hospital preparations. Methods The tests were carried out according to the requirements of provision 1105,1106 and 1107 of rules of preparation in volume IV of Chinese pharmacopoeia 2015 edi...
Objective To establish microbial limit test methods for 6 hospital preparations. Methods The tests were carried out according to the requirements of provision 1105,1106 and 1107 of rules of preparation in volume IV of Chinese pharmacopoeia 2015 edi...
2019, 37(6): 532-536.
doi: 10.3969/j.issn.1006-0111.2019.06.012
Abstract:
Objective To revise and improve the quality standard for Shugan Hewei pills. Methods TLC was used for the identification of costustoot、fingered citrona and orange peel.The content of norisoboldine,albiflorin,paeoniflorin,pentagalloylglucose and hes...
Objective To revise and improve the quality standard for Shugan Hewei pills. Methods TLC was used for the identification of costustoot、fingered citrona and orange peel.The content of norisoboldine,albiflorin,paeoniflorin,pentagalloylglucose and hes...
2019, 37(6): 537-542.
doi: 10.3969/j.issn.1006-0111.2019.06.013
Abstract:
Objective To screen out the optimal conditions for extraction and purification of total flavonoids from the herb pair of Scutellariae barbatae and Hedyotis diffusa. Methods Single factor and L9(34) orthogonal experiment was designed with the extrac...
Objective To screen out the optimal conditions for extraction and purification of total flavonoids from the herb pair of Scutellariae barbatae and Hedyotis diffusa. Methods Single factor and L9(34) orthogonal experiment was designed with the extrac...
2019, 37(6): 543-547,576.
doi: 10.3969/j.issn.1006-0111.2019.06.014
Abstract:
Objective To establish an ultra-high performance liquid chromatography (UPLC) fingerprint of Shenkang injection and identify the common peaks of Shenkang injection fingerprint. Methods The UPLC method was established by employing ACQUITY UPLC® CSH-...
Objective To establish an ultra-high performance liquid chromatography (UPLC) fingerprint of Shenkang injection and identify the common peaks of Shenkang injection fingerprint. Methods The UPLC method was established by employing ACQUITY UPLC® CSH-...
2019, 37(6): 548-551,570.
doi: 10.3969/j.issn.1006-0111.2019.06.015
Abstract:
Objective To reduce the unreasonable medical expenditure and improve the level of clinical rational drug by strengthening the supervision of adjuvant drug use. Methods The regionally integrated medical database and standardized basic drug informati...
Objective To reduce the unreasonable medical expenditure and improve the level of clinical rational drug by strengthening the supervision of adjuvant drug use. Methods The regionally integrated medical database and standardized basic drug informati...
2019, 37(6): 552-558.
doi: 10.3969/j.issn.1006-0111.2019.06.016
Abstract:
Objective To optimize the formulation and preparation technology of N-acetylcysteine(NAC) injection based on the concept of quality by design(QbD). Methods Using QbD as the guidance,the critical quality attributes affecting the quality of the injec...
Objective To optimize the formulation and preparation technology of N-acetylcysteine(NAC) injection based on the concept of quality by design(QbD). Methods Using QbD as the guidance,the critical quality attributes affecting the quality of the injec...
2019, 37(6): 559-562.
doi: 10.3969/j.issn.1006-0111.2019.06.017
Abstract:
Objective To investigate the role of clinical pharmacists in anti-tumor therapy in patients with advanced rectal neuroendocrine tumors. Methods Clinical pharmacists participated in the pharmacy service of a patient with advanced rectal neuroendocri...
Objective To investigate the role of clinical pharmacists in anti-tumor therapy in patients with advanced rectal neuroendocrine tumors. Methods Clinical pharmacists participated in the pharmacy service of a patient with advanced rectal neuroendocri...
2019, 37(6): 563-570.
doi: 10.3969/j.issn.1006-0111.2019.06.018
Abstract:
Objective To investigate the efficacy and safety of S-1 monotherapy or combined with platinum chemotherapy in the treatment of patients with advanced NSCLC. Methods Systematic searches were performed for randomized controlled trials with the CNKI,P...
Objective To investigate the efficacy and safety of S-1 monotherapy or combined with platinum chemotherapy in the treatment of patients with advanced NSCLC. Methods Systematic searches were performed for randomized controlled trials with the CNKI,P...
2019, 37(6): 571-576.
doi: 10.3969/j.issn.1006-0111.2019.06.019
Abstract:
Objective To explore the general rule of medication usage in retired military personnel in the sanatorium. Methods The SQL statement was used to extract the electronic prescription data of all outpatients of 2015-retired military personnel of a thi...
Objective To explore the general rule of medication usage in retired military personnel in the sanatorium. Methods The SQL statement was used to extract the electronic prescription data of all outpatients of 2015-retired military personnel of a thi...
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