Qualitystandard for Shugan Hewei pills

HU Dan; YIN Ming; CAO Hong; SHAN Tingting; ZHANG Guiying

doi:10.3969/j.issn.1006-0111.2019.06.012

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Objective To revise and improve the quality standard for Shugan Hewei pills. Methods TLC was used for the identification of costustoot、fingered citrona and orange peel.The content of norisoboldine,albiflorin,paeoniflorin,pentagalloylglucose and hesperidin was determined by HPLC. Results Costustoot、fingered citrona and orange peel could be detected by TLC.Norisoboldine,albiflorin,paeoniflorin,pentagalloylglucose and hesperidin were well separated under the chromatographic condition.The average recovery was 98.44%(RSD=1.84%)、100.99%(RSD=1.86%)、99.04%(RSD=1.82%)、100.15%(RSD=1.98%)、101.61%(RSD=1.82%)。 Conclusion The method is simple and accurate,reproducible,and can be used to control the quality of the preparation.

Qualitystandard for Shugan Hewei pills

1. General Station for Drug and Instrument Supervision and Control, Joint Logistics Support Force, PLA, Beijing 100166, China

2. The Emergency department of The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing 100853, China

Received Date: 2019-05-07

Rev Recd Date: 2019-11-04

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Abstract: Objective To revise and improve the quality standard for Shugan Hewei pills. Methods TLC was used for the identification of costustoot、fingered citrona and orange peel.The content of norisoboldine,albiflorin,paeoniflorin,pentagalloylglucose and hesperidin was determined by HPLC. Results Costustoot、fingered citrona and orange peel could be detected by TLC.Norisoboldine,albiflorin,paeoniflorin,pentagalloylglucose and hesperidin were well separated under the chromatographic condition.The average recovery was 98.44%(RSD=1.84%)、100.99%(RSD=1.86%)、99.04%(RSD=1.82%)、100.15%(RSD=1.98%)、101.61%(RSD=1.82%)。 Conclusion The method is simple and accurate,reproducible,and can be used to control the quality of the preparation.

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Reference (9)

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Qualitystandard for Shugan Hewei pills

doi: 10.3969/j.issn.1006-0111.2019.06.012

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