2011 Vol. 29, No. 2
Display Method:
2011, 29(2): 81-82,88.
Abstract:
The NALP3 inflammasome , a novel discovered plasmosin , is in-volved in immune inflammatory response . Recent studies indicated that the NALP3 inflammasome had close association with Alzheimer's disease . In this paper , the association of the NALP3 ...
The NALP3 inflammasome , a novel discovered plasmosin , is in-volved in immune inflammatory response . Recent studies indicated that the NALP3 inflammasome had close association with Alzheimer's disease . In this paper , the association of the NALP3 ...
2011, 29(2): 83-88.
Abstract:
Danshensu is the major water-soluble phenolic acids of Danshen. It possessed diverse pharmacological effects, especially the protective effects on cardiovascular diseases. Due to its significant pharmacological activities, synthesis of danshensu deri...
Danshensu is the major water-soluble phenolic acids of Danshen. It possessed diverse pharmacological effects, especially the protective effects on cardiovascular diseases. Due to its significant pharmacological activities, synthesis of danshensu deri...
2011, 29(2): 89-92,116.
Abstract:
In the last few years, inhibitors of the type 2 sodium glucose co-transporters (SGLT2) had been the subject of novel approach to treating diabetes. SGLT2 played a major role in physiology of glucose reabsorption from proximal part of kidney. The bloc...
In the last few years, inhibitors of the type 2 sodium glucose co-transporters (SGLT2) had been the subject of novel approach to treating diabetes. SGLT2 played a major role in physiology of glucose reabsorption from proximal part of kidney. The bloc...
2011, 29(2): 93-96,119.
Abstract:
Objective To review the micro-dialysis coupled with chromatographic technologies in pharmaceutical analysis in vivo. Methods The relevant literatures were collected to make a summary of microdialysis coupled with chromatography technology in pharmace...
Objective To review the micro-dialysis coupled with chromatographic technologies in pharmaceutical analysis in vivo. Methods The relevant literatures were collected to make a summary of microdialysis coupled with chromatography technology in pharmace...
2011, 29(2): 97-100.
Abstract:
Objective To express and purify the human ribosomal protein S3a and study the subcellular localization of human ribosomal protein S3a. Methods The RPS3a gene was obtained by RT-PCR, total RNA extracted from human HEK293 cell as the template,and clone...
Objective To express and purify the human ribosomal protein S3a and study the subcellular localization of human ribosomal protein S3a. Methods The RPS3a gene was obtained by RT-PCR, total RNA extracted from human HEK293 cell as the template,and clone...
2011, 29(2): 101-104,108.
Abstract:
Objective To prepare felodipine sustained release tablet and evaluate the similitude of release rate with original preparation. Methods Matrix technology was used. felodipine sustained release tablet was prepared through studying the influence of mat...
Objective To prepare felodipine sustained release tablet and evaluate the similitude of release rate with original preparation. Methods Matrix technology was used. felodipine sustained release tablet was prepared through studying the influence of mat...
2011, 29(2): 105-108.
Abstract:
Objective To optimize the decolorization technology of Oxytropis falcata total flavones with active carbon. Methonds Temperature, stirring time and the content of active carbon were used as the orthogonal experiment factors. The colour of filtrate, t...
Objective To optimize the decolorization technology of Oxytropis falcata total flavones with active carbon. Methonds Temperature, stirring time and the content of active carbon were used as the orthogonal experiment factors. The colour of filtrate, t...
2011, 29(2): 109-110,130.
Abstract:
Objective To estiblish a method of determining sodium Danshensu in rat plasma by HPLC-MS/MS. Methods sodium Danshensu was extrated for determination by HPLC-MS/MS. Analytical column was Diamonsil C18 (4.6 mm×200 mm ,5 μm). The mobile phase was methan...
Objective To estiblish a method of determining sodium Danshensu in rat plasma by HPLC-MS/MS. Methods sodium Danshensu was extrated for determination by HPLC-MS/MS. Analytical column was Diamonsil C18 (4.6 mm×200 mm ,5 μm). The mobile phase was methan...
2011, 29(2): 111-113.
Abstract:
Objective To investigate the effects of pravastatin on nitric oxide production in endothelial progenitor cells. Methods Total mononuclear cells(MNCs) were isolated from peripheral blood by Ficoll density gradient centrifugation,and cultured in vitro....
Objective To investigate the effects of pravastatin on nitric oxide production in endothelial progenitor cells. Methods Total mononuclear cells(MNCs) were isolated from peripheral blood by Ficoll density gradient centrifugation,and cultured in vitro....
2011, 29(2): 114-116.
Abstract:
Objective To optimize the synthesis of photosensitizer purpurin-18(1). Methods Target compound 1 was synthesized through air oxidation and simultaneously ring cleavage of pheophorbide a (2) in presence of alkali. Four main factors influencing synthet...
Objective To optimize the synthesis of photosensitizer purpurin-18(1). Methods Target compound 1 was synthesized through air oxidation and simultaneously ring cleavage of pheophorbide a (2) in presence of alkali. Four main factors influencing synthet...
2011, 29(2): 117-119.
Abstract:
Objective To evaluate the efficacy and safety of cimetidine on Mycoplasma pneumoniae infection. Methonds 80 MPI patients were selected and randomized into the observation group and the control group averagely. The two groups were treated with azithro...
Objective To evaluate the efficacy and safety of cimetidine on Mycoplasma pneumoniae infection. Methonds 80 MPI patients were selected and randomized into the observation group and the control group averagely. The two groups were treated with azithro...
2011, 29(2): 120-121,148.
Abstract:
Objective To establish the method of bacterial endotoxin test for compound sodium lactate injection No.3. Methods The method based on the bacterial endotoxin test in Chinese pharmacopoeia 2005 edition was used. Results Neither inhibition nor enhancem...
Objective To establish the method of bacterial endotoxin test for compound sodium lactate injection No.3. Methods The method based on the bacterial endotoxin test in Chinese pharmacopoeia 2005 edition was used. Results Neither inhibition nor enhancem...
2011, 29(2): 122-124.
Abstract:
Objective To establish a sample preparation restricted access material (RAM) HPLC method for the quantification of donepezil in human serum. Method The sample was prepocessed by LiChrospher ADS C18 (25 mm × 4 mm,25 μm) as pre-column and analyzed by ...
Objective To establish a sample preparation restricted access material (RAM) HPLC method for the quantification of donepezil in human serum. Method The sample was prepocessed by LiChrospher ADS C18 (25 mm × 4 mm,25 μm) as pre-column and analyzed by ...
2011, 29(2): 125-127.
Abstract:
Objective To investigate the effect of temperature and humidity on the stability of procaine hydrochloride injection. Methods Three batches of the test samples were stored in condition of 40±2 centigrade, relative humidity 75%±5% for 0 month,2 months...
Objective To investigate the effect of temperature and humidity on the stability of procaine hydrochloride injection. Methods Three batches of the test samples were stored in condition of 40±2 centigrade, relative humidity 75%±5% for 0 month,2 months...
2011, 29(2): 128-130.
Abstract:
Objective To establish a method for the detection of bacterial endotoxin in extracts injection from rabbit skin inflamed by vaccinia virus. Methods The interference test was carried out according to the guideline and procedure specified in appendix Ⅺ...
Objective To establish a method for the detection of bacterial endotoxin in extracts injection from rabbit skin inflamed by vaccinia virus. Methods The interference test was carried out according to the guideline and procedure specified in appendix Ⅺ...
2011, 29(2): 131-134,160.
Abstract:
Objective To mine the association rules in and to identify the patterns of the prescription. Methods PASW Modeler 13 was applied to establish Apriori model and analyze the data. Results In 47 132 prescriptions, the drugs for prophylaxis and treatment...
Objective To mine the association rules in and to identify the patterns of the prescription. Methods PASW Modeler 13 was applied to establish Apriori model and analyze the data. Results In 47 132 prescriptions, the drugs for prophylaxis and treatment...
2011, 29(2): 135-137.
Abstract:
Objective To investigate the system of emergency medical supply and enhance the efficiency of drug supply in emergency. Methods Characteristics of emergency medicine were analyzed, the scope, principles and problems of medicine selection were determi...
Objective To investigate the system of emergency medical supply and enhance the efficiency of drug supply in emergency. Methods Characteristics of emergency medicine were analyzed, the scope, principles and problems of medicine selection were determi...
2011, 29(2): 138-138,155.
Abstract:
The important factors which ensuring safe drug use of patients was to use drug beyond their expiry date. A method of changing expired drugs back for free which was built up to strengthen the administration in drug validity duration, improvement the s...
The important factors which ensuring safe drug use of patients was to use drug beyond their expiry date. A method of changing expired drugs back for free which was built up to strengthen the administration in drug validity duration, improvement the s...
2011, 29(2): 139-141,145.
Abstract:
Objective To investigate the utilization of perioperative antibacterial agents in Fuxing Hospital,and provide references for rational use of drugs in clinic. Methods 161 cases of patients were sampled randomly from the operation cases from June to De...
Objective To investigate the utilization of perioperative antibacterial agents in Fuxing Hospital,and provide references for rational use of drugs in clinic. Methods 161 cases of patients were sampled randomly from the operation cases from June to De...
2011, 29(2): 142-145.
Abstract:
Objective To evaluate the status of drug use of the inpatients, summarize the problems of PASS and raise the related suggestion. Methods PASS-nested "Army Health No.1" hospital information system was used to evaluated the drug utilization in these pa...
Objective To evaluate the status of drug use of the inpatients, summarize the problems of PASS and raise the related suggestion. Methods PASS-nested "Army Health No.1" hospital information system was used to evaluated the drug utilization in these pa...
2011, 29(2): 146-148.
Abstract:
Objective To analysis the medication errors and provide prevention methods. Methods The reason of concrete medication error examples in our hospital were analyzed. The policies to prevent medication errors were put forward. Results and conclusion The...
Objective To analysis the medication errors and provide prevention methods. Methods The reason of concrete medication error examples in our hospital were analyzed. The policies to prevent medication errors were put forward. Results and conclusion The...
2011, 29(2): 149-151.
Abstract:
Objective To analyze the characteristics of adverse drug reactions (ADR) induced by aripipirazole tablets. Methods The reports of ADRs published during 2002~2008 induced by aripipirazole tablets were studied. Results Primary symptoms of ADRs induced ...
Objective To analyze the characteristics of adverse drug reactions (ADR) induced by aripipirazole tablets. Methods The reports of ADRs published during 2002~2008 induced by aripipirazole tablets were studied. Results Primary symptoms of ADRs induced ...
2011, 29(2): 153-155.
Abstract:
Species binomial arranged by natural systems to ensure uniform standards of humanity can give a common understanding of life on Earth. Latin name of medicinal plants and crude drugs is an important component of botany and pharmacognosy theory teachin...
Species binomial arranged by natural systems to ensure uniform standards of humanity can give a common understanding of life on Earth. Latin name of medicinal plants and crude drugs is an important component of botany and pharmacognosy theory teachin...
2011, 29(2): 156-157.
Abstract:
Analytical chemistry and pharmaceutical analysis are two major courses of pharmacy.Based on the relations of them, the experimental teaching reform of combining the two courses had been done, to the aims of improving teaching effect , cultivating the...
Analytical chemistry and pharmaceutical analysis are two major courses of pharmacy.Based on the relations of them, the experimental teaching reform of combining the two courses had been done, to the aims of improving teaching effect , cultivating the...
2011, 29(2): 158-160.
Abstract:
In order to strengthen the students' engineering ability, the advanced , scientific contents and various teaching approaches should be adopted in the teaching of pharmaceutical equipment and process design workshop curricula through the scientific an...
In order to strengthen the students' engineering ability, the advanced , scientific contents and various teaching approaches should be adopted in the teaching of pharmaceutical equipment and process design workshop curricula through the scientific an...