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2011 Vol. 29, No. 3

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Progress of molecular imprinting technique in drug separation
KONG Dan-feng, ZHAO Wen, LU Ting-li, HUI Qian-qian, WANG Yun-qing, CHEN Tao
2011, 29(3): 161-164.
Abstract(3028)
Abstract:
Molecularly imprinted polymer drawn much attention for its specific identification function. Among all the research about MIPS, drug separation takes a large proportion. MIPS played an important role in extracting the target-drug from mixture, separa...
Research on poly amino ester as the gene vector
WANG Jiang-feng, LU Ying, ZHONG Yan-qiang
2011, 29(3): 165-168.
Abstract(3074)
Abstract:
With the deepening research of gene therapy, to find an efficient, safe, targeted expression gene vector had become one of the core issues of gene therapy. Poly amino ester (PAE) as a new type of cationic polymer gene carriers, with cheap raw materia...
Progress of oral sustained-release and controlled-release pellets
CHEN Ting, ZHANG Qian, SONG Hong-tao
2011, 29(3): 169-172,192.
Abstract(3667)
Abstract:
Objective To summarize the recent advances in oral sustained/controlled release pellets in international and domestic and prospect its developing future. Methods A great quantity of references were comprehensively reviewed. Results Various kinds of i...
Progress on pharmacological activities and production methods of citrulline
LIU Juan, LU Xin-xin, MENG Hui
2011, 29(3): 173-175,216.
Abstract(4319)
Abstract:
Citrulline was more and more widely used in food and drug industry, health products industry and cosmetics industry because of it's particular pharmacological effects. At present, there were four main methods for producing citrulline: chemical method...
Study on targeted nanoparticles for anticancer therapy
CHEN Ting, LU Ying
2011, 29(3): 176-178,196.
Abstract(3210)
Abstract:
The delivery of chemotherapeutics with targeted nanoparticles in anticancer therapy was a rapidly growing area of research. The advantages of targeted nanoparticles for drug delivery include water solubility increasement, tumor-specific accumulation ...
Advances in the mechanism and medication cure ways of ischemia-reperfusion injury
NI Min, SHEN Fu-ming
2011, 29(3): 179-180,211.
Abstract(3092)
Abstract:
Ischemia-reperfusion injury was a complex course in pathophysiology with many factors which had been implicated in the pathogenesis of a variety of clinical conditions including liver transplantation, and liver resectional surgery. The mechanism of i...
Progress on depression diagnosis by integration of traditional and western medicine
FANG Hui-yu, XU Tao
2011, 29(3): 181-183.
Abstract(3152)
Abstract:
Depression was a common mental disease, which seriously threat people's health. The treatment of depression had become the focus. The present situation of the diagnostic criteria and treatment by integration of traditional and western medicine was in...
The clinical effect of TE chemotherapy regime, with Shenmai injection in the treatment of advanced breast cancer
WANG Jing, ZHAO Na-ping, SHU Li-xin, LIU Bin, ZHANG Wan-lu, YAN Tian-hong, PAN Yong-hua, ZHANG Li
2011, 29(3): 184-187,203.
Abstract(3229)
Abstract:
Objective To investigate the efficacy of Shenmai injection combined TE chemotherapy regime in the treatment of breast cancer and the influence to the quality of life in breast cancer patient. Methods 22 patients with pathologically confirmed advanced...
Experimental study on anti-myocardial ischemia effect of Yixintong
LI Hong-bin, YU Hong, YANG Shi-jie
2011, 29(3): 188-192.
Abstract(3302)
Abstract:
Objective To study the anti-myocardial ischemia effect of Yixintong. Methods The rat myocardial ischemia model was caused by isoprenaline and the experiment myocardial infraction dogs were used to observe the effect of Yixintong. Blood stasis model w...
Synthesis and PTP1B activity of enzyme inhibition of mangiferin derivates
ZHOU Yu, HU Li-na, LUO Jian-fei, YU Shi-chong, WU Qiu-ye
2011, 29(3): 193-196.
Abstract(3165)
Abstract:
Objective To synthetize and conduct PTP1B inhibitory activity experiment of series of novel mangiferin derivates. Methods Different benzyl groups were introduced to mangiferin framework by nucleophilic substitution reaction. All the compounds were sc...
Effect of dissolved oxygen on high density fermentation of E.coli in producing rhG-CSF
CEN Yi, YANG Feng, TONG Yong
2011, 29(3): 197-199,231.
Abstract(2971)
Abstract:
Objective To study the density of the dissolved oxygen(DO) on fermentation of E.coli in producing rhG-CSF. Methods Pure oxygen was used to control DO precisely and to observe the growth of engineered bacteria, the lost of plasmids ,the accumulation o...
Content determination of isofraxidin, rosmarinic acid and astilbin from Herba Sarcandrae in different artifical cultivated
DENG Si-shan, LIU Hong-xu, MA Zhen-jing, XU Rong-qing, HU Ming-fang
2011, 29(3): 200-203.
Abstract(3458)
Abstract:
Objective To determination isofraxidin, rosmarinic acid and astilbin content in different artifical cultivated Herba Sarcandrae. Methods Test sample were classified by plant ports of above and below ground ,and determine by HPLC. A Zorbax SB-C18 colu...
Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis
WANG Jian-fang, SUN Cai-ping, CHEN Xia-lin
2011, 29(3): 204-205,218.
Abstract(3193)
Abstract:
Objective To evaluate the efficacy of indometacin in treatment of pain syndrome related to radiation-induced mucositis. Methods Fifty-eight cases of head and neck malignancies with radio-therapeutic mucositis pain were randomly divided into two group...
Effects of diferent extracts from Bletilla colloid on hemostasis activity in mice
WU Jiu-jian, MENG Yue-liang, ZOU Li-hua, QU Yan
2011, 29(3): 206-207,234.
Abstract(3384)
Abstract:
Objective To determine the active position of Bletilla colloid and offer references to the seleciton of its active composition. Methonds The crude Bletilla colloid was extracted by 70% ethanol permeating , then the petroleum ether extract,ethyl aceta...
Effects of grape seed procyanidins on spatial learning and memory in vascular dementia model of rats
ZHOU Heng, LIN Huan-bing, ZHUO Ye-ye, Bi Bing-tian, Li Guo-xiong, XU Jiang-ping
2011, 29(3): 208-211.
Abstract(2805)
Abstract:
Objective To investigate the effects and possible mechanisms of procyanidins, a polyphenol extracted from grape seeds, on spatial learning and memory in rats model of vascular dementia(VD). Methods Modified Pulsinelli's 4-vessel occlusion (4-VO) meth...
Determination of dimeticone in Type Ⅱ Silicone Gel by Infrared Spectrophotometry
JING Qu-chi, HU Lei, HU Jian-guo
2011, 29(3): 212-213.
Abstract(3397)
Abstract:
Objective To establish a method to determinate dimeticone in type Ⅱ silicone gel by Infrared spectrophotometry. Methods The infrared spectrophotometry was adopted, and the detective wave was 1 262 cm-1. Results The linear range of the calibration of ...
Rapid separation and identification of chemical components in Danxiangguanxin injection by HPLC-TOFMS
LUAN Xiao-lin, ZHANG Hai, WANG Hui, CHEN Jun, ZHANG Guo-qing
2011, 29(3): 214-216.
Abstract(18349)
Abstract:
Objective To separate and identify the components in Danxiangguanxin injection by high performance liquid chromatography time-of-flight mass spectrometry (HPLC-TOFMS). Methods Agilent Zorbax SB-Cl8 column (3.0 mm×100 mm, 3.5 μm) was used for separati...
Study on chemical constituents from Solms-Laubachia lanata
YANG Ai-mei, WANG Li-li
2011, 29(3): 217-218.
Abstract(3094)
Abstract:
Objective To isolate and identify the chemical constituents from the root of Solms-Laubachia lanata Botsch. Methods The compounds were isolated by column chromatography. The structures of the were compounds elucidated by spectroscopic analysis (NMR a...
Evaluation of antibiotics utility in surgical patients withⅠclass incision in our hospital
SHI Jia-na, YE Zuo-wu, YIN Yin
2011, 29(3): 219-220.
Abstract(2805)
Abstract:
Objective To investigate the utility and rationality of antibiotics in surgical patients with I class incision and regulate the method of preventive utility of antibiotics in surgery. Methods 166 patients with surgical operation during 2009 were retr...
Analysis of marked items for special population in drug package inserts of antimicrobial agents
CHEN Guo-ying
2011, 29(3): 221-222,240.
Abstract(3332)
Abstract:
Objective To investigate and analyze the current package inserts of antimicrobial agents and provide references for the further standardization of drug package inserts. Methods A total of 185 package inserts of antimicrobial agents were collected and...
Investigation and analysis to the current situation of pharmacy department in third class A hospitals in shanghai
WEI Ya-dong, ZHANG Xiao-ming, LUAN Zhi-peng, JIANG Li-ling
2011, 29(3): 223-225,237.
Abstract(3052)
Abstract:
Objective To objective reflect and reveal current situation and work mode of the pharmacy department in third class A hospitals in shanghai. Methods Through the questionnaire survey and on-site interviews , data about staffing , content and quantity ...
Comparative study of the health insurance directory entrance procedure of new drug domestic and overseas and the suggestion on the relevant policy in China
CUI Meng-xun, PENG Yi, ZHAO Jin, FANG Tong-yu
2011, 29(3): 226-228.
Abstract(3251)
Abstract:
Four kinds of medical security system models in forgien countries were compared and evaluated. The health insurance list entrance procedrue of new drugs in forgien countries was rapid, scientific, and convenient in evaluation and adminstration. Our c...
Analysis of prescriptions in military personnel outpatients
QIN Chang-xin, FU Qiu-sheng
2011, 29(3): 229-231.
Abstract(3289)
Abstract:
Objective To analyze the rationality and status of drug utilization in military personnel outpatients by the index of rational drug use recommended by WHO. Methods 3000 prescriptions from Match to December in 2009 were randomly collected and analyzed...
The application of Meta analysis in clinical pharmacy
CHEN Wei, YU Wei-guo, SHI Hai-bo, ZHAO Hai, LU Xiao-yan
2011, 29(3): 232-234.
Abstract(3446)
Abstract:
Objective To discuss the application and the use experience of the Meta analysis in clinical pharmacy. Methods MEDLINE,ScienceDirect and other databases were searched. The literature and examples of Meta analysis application were summarized, synthesi...
Causes and countermeasures of inconformity of goods and accounts in hospital drug checking
ZHANG Xian-li, HUO Hua, ZAI Li
2011, 29(3): 235-237.
Abstract(3832)
Abstract:
Objective To discuss the methods to improve accounts and matter consentaneous rates in drug checking works under the hospital management information system. Methods The problems discovered in drug checking works were collected , the causes of bringin...
Analysis and inspiration of advantages and disadvantages of military and local drug bidding models
XIAO Jun
2011, 29(3): 238-240.
Abstract(2946)
Abstract:
Objective To investigate the current military online and centralized bidding medicine model and situation of local implementation of bidding essential drugs, and to explore the drug bidding model with military characteristics. Methods Literature revi...