Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 29 Issue 3
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2011  >  29(3): 204-205,218

WANG Jian-fang, SUN Cai-ping, CHEN Xia-lin. Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 204-205,218.
Citation: WANG Jian-fang, SUN Cai-ping, CHEN Xia-lin. Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 204-205,218.
shu

Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis

  • Shaoxing People's Hospital,Shaoxing 312000,China

  • Received Date: 2010-07-06
  • Rev Recd Date: 2010-10-24
  • Objective To evaluate the efficacy of indometacin in treatment of pain syndrome related to radiation-induced mucositis. Methods Fifty-eight cases of head and neck malignancies with radio-therapeutic mucositis pain were randomly divided into two groups: one group were treated with both indometacin and normal therapy, the other group received normal therapy. Results By using the indometacin, the pain relief rate during the radiotherapy was 89.7%, which was 27.6% in control group. In the treatment group, the body weight stable ratio in radiation and after radiation are 69.0% and 37.9%, which was 34.5% and 17.2% in control group. The chief side effects were reduced. Conclusion Indometacin could relieve pain with radio-therapeutic mucositis pain in radiotherapy to head and neck malignancies treated and should be further evaluated prospectively in controlled clinical trials.
  • [1] Ang kk. Altered fractionation in the management of head and neck cancer[J]. Int J Radiat Biol, 1998, 73 (4) : 395. [2] 谭榜宪,张有望,胡超苏,等.鼻咽癌常规分割放疗中的时间剂量效应关系[J].中华放射疼痛学杂志,1998 ,7(1) :41. [3] Weissman DE ,Janjan N,Byhardt RW,et al.Assessment of pain during head and neck irradiation[J].J Pain Symptom Manage,1989,4(2):90. [4] 程 晶,马 虹,薛 军,等.芬太尼透皮帖剂治疗鼻咽癌放疗相关性口腔粘膜炎所致疼痛的疗效观察[J].肿瘤防治研究,2008,35(6):442. [5] 高文君,郑慧娟,叶纯华,等. 吲哚美辛栓缓解Ⅲ型前列腺炎患者疼痛症状的初步观察[J].浙江临床医学,2007,9(5):607. [6] Gallo O,Franchi A,Magnelli L.Cyclooxygenase-2 pathway correlates with VEGF expression in head and neck cancer ,Implications for tumor angiogenesis and metastasis[J].Neoplasia,2001,3:53.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(2982) PDF downloads(259) Cited by()

Related
Proportional views

Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis

  • Shaoxing People's Hospital,Shaoxing 312000,China
  • Received Date: 2010-07-06
  • Rev Recd Date: 2010-10-24

Abstract: Objective To evaluate the efficacy of indometacin in treatment of pain syndrome related to radiation-induced mucositis. Methods Fifty-eight cases of head and neck malignancies with radio-therapeutic mucositis pain were randomly divided into two groups: one group were treated with both indometacin and normal therapy, the other group received normal therapy. Results By using the indometacin, the pain relief rate during the radiotherapy was 89.7%, which was 27.6% in control group. In the treatment group, the body weight stable ratio in radiation and after radiation are 69.0% and 37.9%, which was 34.5% and 17.2% in control group. The chief side effects were reduced. Conclusion Indometacin could relieve pain with radio-therapeutic mucositis pain in radiotherapy to head and neck malignancies treated and should be further evaluated prospectively in controlled clinical trials.

WANG Jian-fang, SUN Cai-ping, CHEN Xia-lin. Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 204-205,218.
Citation: WANG Jian-fang, SUN Cai-ping, CHEN Xia-lin. Therapeutic efficacy of indometacin in treatment of pain related to radiation-induced mucositis[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 204-205,218.
shu

    HTML

Reference (1)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return