2011 Vol. 29, No. 1
Display Method:
2011, 29(1): 1-3,14.
Abstract:
interleukin-1 receptor-associated kinase 4 (IRAK-4) is a key molecular which participates in the innate immune processes. It belongs to the IRAK family with the other three members: IRAK-1, IRAK-2, and IRAK-M. However, It has been found that IRAK-4 p...
interleukin-1 receptor-associated kinase 4 (IRAK-4) is a key molecular which participates in the innate immune processes. It belongs to the IRAK family with the other three members: IRAK-1, IRAK-2, and IRAK-M. However, It has been found that IRAK-4 p...
2011, 29(1): 4-7,67.
Abstract:
Objective To presente a view of chemical and pharmacological study on Dendropanax and lay a solid foundation for further research. Methods Relevant literature of Dendropanax were searched and summarized. Results and Conclusion The main chemical const...
Objective To presente a view of chemical and pharmacological study on Dendropanax and lay a solid foundation for further research. Methods Relevant literature of Dendropanax were searched and summarized. Results and Conclusion The main chemical const...
2011, 29(1): 8-10,61.
Abstract:
Despite the advantages of chitosan as a non-viral gene delivery vector, the application of this system is significantly limited by its poor solubility (the amino groups on chitosan are only partially protonated at physiological pH 7.4), poor stabilit...
Despite the advantages of chitosan as a non-viral gene delivery vector, the application of this system is significantly limited by its poor solubility (the amino groups on chitosan are only partially protonated at physiological pH 7.4), poor stabilit...
2011, 29(1): 11-14.
Abstract:
nicotinamide phosphoribosyl transferase (Nampt) is an essential protein with a variety of physiological functions and performs potential functions on many diseases such as cardiovascular diseases, diabetes, cancer and autoimmune diseases. It is of gr...
nicotinamide phosphoribosyl transferase (Nampt) is an essential protein with a variety of physiological functions and performs potential functions on many diseases such as cardiovascular diseases, diabetes, cancer and autoimmune diseases. It is of gr...
2011, 29(1): 15-16,70.
Abstract:
Objective To establish a method for determining Atorvastatin in human plasma by LC-MS-MS. Methods Atorvastatin was extracted for determination by LC-MS-MS. Analytical column was Thermo BioBasic-C8(2.1 mm×100 mm,5 μm). The mobile phase was acetonitril...
Objective To establish a method for determining Atorvastatin in human plasma by LC-MS-MS. Methods Atorvastatin was extracted for determination by LC-MS-MS. Analytical column was Thermo BioBasic-C8(2.1 mm×100 mm,5 μm). The mobile phase was acetonitril...
2011, 29(1): 17-20.
Abstract:
Objective To prepare 4'-alkoxy-1,1'-bisphenyl-4-carboxylic acid lipotripeptides , which is the key intermediates for total synthesis of novel caspofungin-like cyclohexalipopeptide antifungal agents. Methods Starting from Pro-O-t-Bu , the target compo...
Objective To prepare 4'-alkoxy-1,1'-bisphenyl-4-carboxylic acid lipotripeptides , which is the key intermediates for total synthesis of novel caspofungin-like cyclohexalipopeptide antifungal agents. Methods Starting from Pro-O-t-Bu , the target compo...
2011, 29(1): 24-26,40.
Abstract:
Objective To investigate the bio-efficacy of seven skin-lighteners on melanocytes in vitro. Methods After B-16 melanoma cells were treated with skin-lightener, the tyrosinase activity, the melanin content and cell viability were measured by utilizati...
Objective To investigate the bio-efficacy of seven skin-lighteners on melanocytes in vitro. Methods After B-16 melanoma cells were treated with skin-lightener, the tyrosinase activity, the melanin content and cell viability were measured by utilizati...
2011, 29(1): 27-28.
Abstract:
Objective To design and synthetize new derivatives of aspartic acid from L-Asp-1-OtBu and to study the importance of new derivatives in the synthesis of cyclic peptide. Methods Starting from L-Asp-1-OtBu, the benzyl was introduced on the four positio...
Objective To design and synthetize new derivatives of aspartic acid from L-Asp-1-OtBu and to study the importance of new derivatives in the synthesis of cyclic peptide. Methods Starting from L-Asp-1-OtBu, the benzyl was introduced on the four positio...
2011, 29(1): 29-30,77.
Abstract:
Objective To explore an easily-controled, environmentally benign synthetic method of 4-phenyl-5-ethoxycarbonyl-6-methyl-3,4-dihydropirimidine-2(1H)-one. Methods 4-phenyl-5-ethoxy-carbonyl-6-methyl-3,4-dihydropirimidine-2(1H)-one was synthesized from ...
Objective To explore an easily-controled, environmentally benign synthetic method of 4-phenyl-5-ethoxycarbonyl-6-methyl-3,4-dihydropirimidine-2(1H)-one. Methods 4-phenyl-5-ethoxy-carbonyl-6-methyl-3,4-dihydropirimidine-2(1H)-one was synthesized from ...
2011, 29(1): 31-32.
Abstract:
Objective To establish a headspace capillary gas chromatgraphy for determination the residual organic solvents in piroxicam. Methods The residual solvents in piroxicam which are methanol , ethanol, toluene and dimethybenzene were determined by headsp...
Objective To establish a headspace capillary gas chromatgraphy for determination the residual organic solvents in piroxicam. Methods The residual solvents in piroxicam which are methanol , ethanol, toluene and dimethybenzene were determined by headsp...
2011, 29(1): 33-34,37.
Abstract:
Objective To establish a RP-HPLC method for determination of a flavonol glycoside in Equisetum hiemale. Methods The separation was performed on Calesil ODS-100(250 mm×4.6 mm,5 μm). Mobile phase consisted of methanol-water (45:55) with flow rate of 1....
Objective To establish a RP-HPLC method for determination of a flavonol glycoside in Equisetum hiemale. Methods The separation was performed on Calesil ODS-100(250 mm×4.6 mm,5 μm). Mobile phase consisted of methanol-water (45:55) with flow rate of 1....
2011, 29(1): 35-37.
Abstract:
Objective To investigate the identification capability of portable Raman spectrometer for hypoglycemic drugs. Methods The Raman spectra of the standard substance of active pharmaceutical ingredient of the hypoglycemic drugs and their corresponding pr...
Objective To investigate the identification capability of portable Raman spectrometer for hypoglycemic drugs. Methods The Raman spectra of the standard substance of active pharmaceutical ingredient of the hypoglycemic drugs and their corresponding pr...
2011, 29(1): 38-40.
Abstract:
Objective To study the fluorescence properties and analysis method of Tanshinone IIA. Methods Influencial factors including acidic media, the concentrations of substrate on the fluorescence intensity were studied. The stability of fluorescence of Tan...
Objective To study the fluorescence properties and analysis method of Tanshinone IIA. Methods Influencial factors including acidic media, the concentrations of substrate on the fluorescence intensity were studied. The stability of fluorescence of Tan...
2011, 29(1): 41-44.
Abstract:
Dronedarone is analogues as amiodarone, the structure is not iodine, reducing iodine-induced organ toxicity, is one of the new anti-arrhythmia drugs. on July 1, 2009 , It has been approved by FDA for the treatment of atrial fibrillation or atrial flu...
Dronedarone is analogues as amiodarone, the structure is not iodine, reducing iodine-induced organ toxicity, is one of the new anti-arrhythmia drugs. on July 1, 2009 , It has been approved by FDA for the treatment of atrial fibrillation or atrial flu...
2011, 29(1): 45-47,57.
Abstract:
Objective To advance the data analysis of hospital drug utilization. Methods The analysis system is designed for the subject of "drug utilization", which was based on HIS, the theory of multimentional cube and OLAP. "Drug", "patient", "institution" a...
Objective To advance the data analysis of hospital drug utilization. Methods The analysis system is designed for the subject of "drug utilization", which was based on HIS, the theory of multimentional cube and OLAP. "Drug", "patient", "institution" a...
2011, 29(1): 48-49.
Abstract:
The fundamental aim of Military Hospital is to provide services to basic level troops. It was the key research point of military hospital to study how to express the advantage of talented personnel and technology to improve the services level to basi...
The fundamental aim of Military Hospital is to provide services to basic level troops. It was the key research point of military hospital to study how to express the advantage of talented personnel and technology to improve the services level to basi...
2011, 29(1): 50-51.
Abstract:
Objective To improve the effectiveness and efficiency of the total parenteral nutrition (TPN) prescriptions inspection. Method Based on the original hospital information system, Powerbuilder 6.5 system front database development tool was used and the...
Objective To improve the effectiveness and efficiency of the total parenteral nutrition (TPN) prescriptions inspection. Method Based on the original hospital information system, Powerbuilder 6.5 system front database development tool was used and the...
2011, 29(1): 52-54.
Abstract:
objective To review decision-making models for national pharmaceutical stockpile. Methods using the method of literature investigation, logical analysis to compared storage models according to the characteristics of drugs. Results demand of national ...
objective To review decision-making models for national pharmaceutical stockpile. Methods using the method of literature investigation, logical analysis to compared storage models according to the characteristics of drugs. Results demand of national ...
2011, 29(1): 55-57.
Abstract:
According to characteristics of military operations other than war,and the analysis of medical supply, some key points and difficult points in medical supply were found,such as the unbalance of demands and supplies of out of time in supplies. The lim...
According to characteristics of military operations other than war,and the analysis of medical supply, some key points and difficult points in medical supply were found,such as the unbalance of demands and supplies of out of time in supplies. The lim...
2011, 29(1): 58-61.
Abstract:
Combined with the situation of our country and military, according to the research basis of defense mobilization and defense health mobilization, the civillian medical material mobilization, which was still a special blank research field was analyzed...
Combined with the situation of our country and military, according to the research basis of defense mobilization and defense health mobilization, the civillian medical material mobilization, which was still a special blank research field was analyzed...
2011, 29(1): 62-64.
Abstract:
Objective To grasp the status and analyze the problems of drug utility in troops below division level at ordinary times. To put forward the suggestion and countermeasures to promote the rational drug utility in troops below division level at ordinary...
Objective To grasp the status and analyze the problems of drug utility in troops below division level at ordinary times. To put forward the suggestion and countermeasures to promote the rational drug utility in troops below division level at ordinary...
2011, 29(1): 65-67.
Abstract:
Objective To analyze the medicine guarantee status for the chemical emergencies and supply the relevant suggestions. Methods Literature analysis was used to study the development of chemical emergency medicine, and the coping strategies were proposed...
Objective To analyze the medicine guarantee status for the chemical emergencies and supply the relevant suggestions. Methods Literature analysis was used to study the development of chemical emergency medicine, and the coping strategies were proposed...
2011, 29(1): 68-70.
Abstract:
Objective To explore the problems and put forward the countermeasures of emergency medical material support in MOOTW. Methods According to the basic characteristics of emergency medical material support in MOOTW , the shortage of collection, reservat...
Objective To explore the problems and put forward the countermeasures of emergency medical material support in MOOTW. Methods According to the basic characteristics of emergency medical material support in MOOTW , the shortage of collection, reservat...
2011, 29(1): 71-74.
Abstract:
By analyzing the current situation and shortcomings of clinical pharmaceutical postgraduates' education model, the appropriate cultivating model which to satisfy the need of clinical pharmaceutical work were explored, combining the development of cli...
By analyzing the current situation and shortcomings of clinical pharmaceutical postgraduates' education model, the appropriate cultivating model which to satisfy the need of clinical pharmaceutical work were explored, combining the development of cli...
2011, 29(1): 75-77.
Abstract:
On the basis of plant exists in campus and campus internet currently, the significance and necessity of establishing the campus plant website were illustrated, in accordance with teaching characteristics of the pharmaceutical botany. The contents wou...
On the basis of plant exists in campus and campus internet currently, the significance and necessity of establishing the campus plant website were illustrated, in accordance with teaching characteristics of the pharmaceutical botany. The contents wou...