2018 Vol. 36, No. 1
Display Method:
2018, 36(1): 1-8.
doi: 10.3969/j.issn.1006-0111.2018.01.001
Abstract:
Paclitaxel is a natural compound with efficient broad-spectrum antitumor activity. However, the clinical application has been limited owing to the undesirable drawbacks, such as the poor water-solubility, cardiovascular toxicity and neurotoxicity. Th...
Paclitaxel is a natural compound with efficient broad-spectrum antitumor activity. However, the clinical application has been limited owing to the undesirable drawbacks, such as the poor water-solubility, cardiovascular toxicity and neurotoxicity. Th...
2018, 36(1): 9-12.
doi: 10.3969/j.issn.1006-0111.2018.01.002
Abstract:
Knee osteoarthritis (KOA) is a common chronic degenerative disease in the elderly population. It is characterized by knee-joint pain, swelling, morning stiffness and seriously affects the patients' motor function and physical health. So far, there is...
Knee osteoarthritis (KOA) is a common chronic degenerative disease in the elderly population. It is characterized by knee-joint pain, swelling, morning stiffness and seriously affects the patients' motor function and physical health. So far, there is...
2018, 36(1): 13-17.
doi: 10.3969/j.issn.1006-0111.2018.01.003
Abstract:
Core-shell-type lipid-polymer hybrid nanoparticles(CSLPHNs) are composed by a biodegradable polymeric core coated with single or multiple layers of biomimetic lipids, which combine the benefits of polymeric nanoparticles and liposomes. CSLPHNs have t...
Core-shell-type lipid-polymer hybrid nanoparticles(CSLPHNs) are composed by a biodegradable polymeric core coated with single or multiple layers of biomimetic lipids, which combine the benefits of polymeric nanoparticles and liposomes. CSLPHNs have t...
2018, 36(1): 18-23.
doi: 10.3969/j.issn.1006-0111.2018.01.004
Abstract:
Surface plasmon resonance(SPR) is an optical phenomenon arises from mass changes on sensors based on interaction between substances, which could monitor the interaction between biomolecules quickly and accurately. It has the advantage of label-free, ...
Surface plasmon resonance(SPR) is an optical phenomenon arises from mass changes on sensors based on interaction between substances, which could monitor the interaction between biomolecules quickly and accurately. It has the advantage of label-free, ...
2018, 36(1): 24-29.
doi: 10.3969/j.issn.1006-0111.2018.01.005
Abstract:
As a traditional Chinese medicine, Anemarrhena saponin is one of the main components in Anemarrhena. Many pharmacological activities were reported in recent literatures, such as anti-tumor, anti-senile dementia, improving learning and memory, anti-cl...
As a traditional Chinese medicine, Anemarrhena saponin is one of the main components in Anemarrhena. Many pharmacological activities were reported in recent literatures, such as anti-tumor, anti-senile dementia, improving learning and memory, anti-cl...
2018, 36(1): 30-33,54.
doi: 10.3969/j.issn.1006-0111.2018.01.006
Abstract:
Objective To study the effect of flumazenil on hypnotic mice induced by diazepam and zolpidem, and to evaluate the possibility of flumazenil oral administration. Methods First, Kunming mice were injected intraperitoneally with normal saline and so...
Objective To study the effect of flumazenil on hypnotic mice induced by diazepam and zolpidem, and to evaluate the possibility of flumazenil oral administration. Methods First, Kunming mice were injected intraperitoneally with normal saline and so...
2018, 36(1): 34-39.
doi: 10.3969/j.issn.1006-0111.2018.01.007
Abstract:
Objective To study the protective effect of Fu-Yuan-Xing-Nao decoction (FYXND) on rats with middle cerebral ischemia reperfusion injury. Methods Male Sprague-Dawley rats were randomly divided into sham, ischemia-reperfusion, and low, middle, high ...
Objective To study the protective effect of Fu-Yuan-Xing-Nao decoction (FYXND) on rats with middle cerebral ischemia reperfusion injury. Methods Male Sprague-Dawley rats were randomly divided into sham, ischemia-reperfusion, and low, middle, high ...
2018, 36(1): 40-45.
doi: 10.3969/j.issn.1006-0111.2018.01.008
Abstract:
Objective To evaluate the current situation of rational drug use in medical facilities at all levels in Sichuan province by means of empirical research via WHO/INRUD selected drug use indicators SDUIs. Methods Six sample cities in Sichuan Province...
Objective To evaluate the current situation of rational drug use in medical facilities at all levels in Sichuan province by means of empirical research via WHO/INRUD selected drug use indicators SDUIs. Methods Six sample cities in Sichuan Province...
2018, 36(1): 46-49.
doi: 10.3969/j.issn.1006-0111.2018.01.009
Abstract:
Objective To investigate the extraction process of Yuchang granules. Methods The extraction process was optimized by orthogonal experiment based on the content of berberine, atractylodes lactone Ⅰ and the extraction yield. Results Through the vi...
Objective To investigate the extraction process of Yuchang granules. Methods The extraction process was optimized by orthogonal experiment based on the content of berberine, atractylodes lactone Ⅰ and the extraction yield. Results Through the vi...
2018, 36(1): 50-54.
doi: 10.3969/j.issn.1006-0111.2018.01.010
Abstract:
Objective To study the anti-oxidation properties of Zn2+-quercetin complexes. Methods The binding stoichiometric ratios and the binding constant of Zn2+ to quercetin were measured with UV-Vis spectroscopy. The binding sites on quercetin were deter...
Objective To study the anti-oxidation properties of Zn2+-quercetin complexes. Methods The binding stoichiometric ratios and the binding constant of Zn2+ to quercetin were measured with UV-Vis spectroscopy. The binding sites on quercetin were deter...
2018, 36(1): 55-60.
doi: 10.3969/j.issn.1006-0111.2018.01.011
Abstract:
Objective To investigate the chemical constituents of the marine sponge Theonella swinhoei collected from the Xisha Islands in the South China Sea. Methods The petroleum ether and dichloromethane extract of the marine sponge T. swinhoei were purif...
Objective To investigate the chemical constituents of the marine sponge Theonella swinhoei collected from the Xisha Islands in the South China Sea. Methods The petroleum ether and dichloromethane extract of the marine sponge T. swinhoei were purif...
2018, 36(1): 61-63,67.
doi: 10.3969/j.issn.1006-0111.2018.01.012
Abstract:
Objective A series of 4 substituted salidroside derivatives were designed and synthesized. Their anti-fatigue effects were investigated. Methods With five-acetyl glucose and different 4-substituted benzyl tyrosols as the starting materials,salidro...
Objective A series of 4 substituted salidroside derivatives were designed and synthesized. Their anti-fatigue effects were investigated. Methods With five-acetyl glucose and different 4-substituted benzyl tyrosols as the starting materials,salidro...
2018, 36(1): 64-67.
doi: 10.3969/j.issn.1006-0111.2018.01.013
Abstract:
Objective To determine the contents of total flavonoids and xanthohumol in hop from 29 different countries and regions. Methods Rutin colorimetric method was used to determine the content of total flavonoids. HPLC-UV method was established for the...
Objective To determine the contents of total flavonoids and xanthohumol in hop from 29 different countries and regions. Methods Rutin colorimetric method was used to determine the content of total flavonoids. HPLC-UV method was established for the...
2018, 36(1): 68-70,79.
doi: 10.3969/j.issn.1006-0111.2018.01.014
Abstract:
Objective To determine the content of paeoniflorin in Fuzhengpingxiao capsule by HPLC method. Methods The content of paeoniflorin were determined by HPLC, and the column was an Agilent Zorbax SB-C18 column (150 mm×4.6 mm, 5 μm); The mobile phase w...
Objective To determine the content of paeoniflorin in Fuzhengpingxiao capsule by HPLC method. Methods The content of paeoniflorin were determined by HPLC, and the column was an Agilent Zorbax SB-C18 column (150 mm×4.6 mm, 5 μm); The mobile phase w...
2018, 36(1): 71-74.
doi: 10.3969/j.issn.1006-0111.2018.01.015
Abstract:
Objective To establish the quality standard for Baibu Zhike syrup. Methods TLC method was used for qualitative identification of Stemonae Radix and Platycodonis Radix. The content of hesperidin in Citri Exocarpium Rubrum was determined by HPLC met...
Objective To establish the quality standard for Baibu Zhike syrup. Methods TLC method was used for qualitative identification of Stemonae Radix and Platycodonis Radix. The content of hesperidin in Citri Exocarpium Rubrum was determined by HPLC met...
2018, 36(1): 75-79.
doi: 10.3969/j.issn.1006-0111.2018.01.016
Abstract:
Objective To study the efficacy and adverse reactions for renal transplant patients conversed from cyclosporine A to tacrolimus. Methods The follow-up data of renal transplant patients conversed from cyclosporine A to tacrolimus were collected. Th...
Objective To study the efficacy and adverse reactions for renal transplant patients conversed from cyclosporine A to tacrolimus. Methods The follow-up data of renal transplant patients conversed from cyclosporine A to tacrolimus were collected. Th...
2018, 36(1): 80-82,87.
doi: 10.3969/j.issn.1006-0111.2018.01.017
Abstract:
Objective To analyze the effect of edaravone combined with ginkgo diterpene lactone in treatment of acute cerebral infarction (ACI) and discuss the better clinical treatment to ACI. Methods 100 cases of ACI and who accepted treatments in our hospit...
Objective To analyze the effect of edaravone combined with ginkgo diterpene lactone in treatment of acute cerebral infarction (ACI) and discuss the better clinical treatment to ACI. Methods 100 cases of ACI and who accepted treatments in our hospit...
2018, 36(1): 83-87.
doi: 10.3969/j.issn.1006-0111.2018.01.018
Abstract:
Objective To explore the role of clinical pharmacists in pharmaceutical care for a pregnant patient with severe acute pancreatitis. Methods Clinical pharmacists participated in the treatments for one severe case of acute pancreatitis in pregnancy....
Objective To explore the role of clinical pharmacists in pharmaceutical care for a pregnant patient with severe acute pancreatitis. Methods Clinical pharmacists participated in the treatments for one severe case of acute pancreatitis in pregnancy....
2018, 36(1): 88-92.
doi: 10.3969/j.issn.1006-0111.2018.01.019
Abstract:
Objective To analyze the regularity and characteristics of 2 621 cases of adverse drug reaction (ADR) occurring in our hospital during 2013-2016, and to explore the factors and causes of ADRs, so as to provide evidence for the continuous improvement...
Objective To analyze the regularity and characteristics of 2 621 cases of adverse drug reaction (ADR) occurring in our hospital during 2013-2016, and to explore the factors and causes of ADRs, so as to provide evidence for the continuous improvement...
2018, 36(1): 93-96.
doi: 10.3969/j.issn.1006-0111.2018.01.020
Abstract:
Objective To investigate the utility behavior of dietary supplement in middle school students from Shenyang and Shanghai. Methods The survey questionnaires were handed out to the middle school students from different grades of 11 schools in Shenya...
Objective To investigate the utility behavior of dietary supplement in middle school students from Shenyang and Shanghai. Methods The survey questionnaires were handed out to the middle school students from different grades of 11 schools in Shenya...
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