SHAO Xueqing, TANG Xiaomeng, YANG Meng, BIAN Jun, LIU Jiyong. Extraction process optimization for Yuchang granules by orthogonal experiment[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(1): 46-49. doi: 10.3969/j.issn.1006-0111.2018.01.009
| Citation:
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SHAO Xueqing, TANG Xiaomeng, YANG Meng, BIAN Jun, LIU Jiyong. Extraction process optimization for Yuchang granules by orthogonal experiment[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(1): 46-49. doi: 10.3969/j.issn.1006-0111.2018.01.009
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Extraction process optimization for Yuchang granules by orthogonal experiment
- 1.
Department of Pharmacy, Changhai Hospital Affiliated to Second Military Medical University, Shanghai 200433, China;Drug and Equipment Section, No. 411 Hospital of PLA, Shanghai 200081, China
- 2.
Department of Pharmacy, Changhai Hospital Affiliated to Second Military Medical University, Shanghai 200433, China
- 3.
Drug and Equipment Section, No. 411 Hospital of PLA, Shanghai 200081, China
- Received Date: 2017-09-20
- Rev Recd Date:
2017-11-06
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Abstract
Objective To investigate the extraction process of Yuchang granules. Methods The extraction process was optimized by orthogonal experiment based on the content of berberine, atractylodes lactone Ⅰ and the extraction yield. Results Through the visual analysis of orthogonal experiment, the analysis of variance and the verification experiments, the optimum extraction process was obtained as follows:extracting 1 h for twice with 10 times water of medicinal herbs and the 70% ethanol depositing concentration. Conclusion This process is consistent and feasible. It is a simple and convenient method to extract Yuchang granules.
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