2017 Vol. 35, No. 6
Display Method:
2017, 35(6): 481-484,489.
doi: 10.3969/j.issn.1006-0111.2017.06.001
Abstract:
In vitro lipolysis model has become a new and promising technique to screen and evaluate oral lipid formulations. This model mimics the gastrointestinal tract environment and well reflects the fate of lipid formulations in GI tract after oral adminis...
In vitro lipolysis model has become a new and promising technique to screen and evaluate oral lipid formulations. This model mimics the gastrointestinal tract environment and well reflects the fate of lipid formulations in GI tract after oral adminis...
2017, 35(6): 485-489.
doi: 10.3969/j.issn.1006-0111.2017.06.002
Abstract:
Flumazenil, a benzodiazepine antagonist, specifically binds the benzodiazepine receptors in central nervous system and reduces the release of gamma-aminobutyric acid. It is used for the reversal of sedative effects of benzodiazepine and benzodiazepin...
Flumazenil, a benzodiazepine antagonist, specifically binds the benzodiazepine receptors in central nervous system and reduces the release of gamma-aminobutyric acid. It is used for the reversal of sedative effects of benzodiazepine and benzodiazepin...
2017, 35(6): 490-494,542.
doi: 10.3969/j.issn.1006-0111.2017.06.003
Abstract:
Osteoporosis (OP) is a systemic bone metabolism disease characterized by a systemic impairment of bone mass, strength, and microarchitecture, which will be result in increasing the propensity of fragility fractures. In recent years, OP becomes a worl...
Osteoporosis (OP) is a systemic bone metabolism disease characterized by a systemic impairment of bone mass, strength, and microarchitecture, which will be result in increasing the propensity of fragility fractures. In recent years, OP becomes a worl...
2017, 35(6): 495-498,529.
doi: 10.3969/j.issn.1006-0111.2017.06.004
Abstract:
Traumatic brain injuries(TBI) have caused severe injuries and deaths all over the world, but so far researchers have not found an effective drug in treating TBI on clinic. However, peptides have gradually been in a hot research with its advantages wh...
Traumatic brain injuries(TBI) have caused severe injuries and deaths all over the world, but so far researchers have not found an effective drug in treating TBI on clinic. However, peptides have gradually been in a hot research with its advantages wh...
2017, 35(6): 499-503.
doi: 10.3969/j.issn.1006-0111.2017.06.005
Abstract:
High-throughput metabolomics have developed very rapidly in recent years and been widely used in medicinal plants research. At present, high-throughput metabolomics mainly applied in the following areas, quality control of medicinal plants by fingerp...
High-throughput metabolomics have developed very rapidly in recent years and been widely used in medicinal plants research. At present, high-throughput metabolomics mainly applied in the following areas, quality control of medicinal plants by fingerp...
2017, 35(6): 504-507.
doi: 10.3969/j.issn.1006-0111.2017.06.006
Abstract:
Objective To establish a simple and sensitive method for the determination of plasma drug concentration in rats after intragastrical and intravenous administration of paclitaxel loaded nanoparticles and to evaluate its pharmacokinetic characteristic...
Objective To establish a simple and sensitive method for the determination of plasma drug concentration in rats after intragastrical and intravenous administration of paclitaxel loaded nanoparticles and to evaluate its pharmacokinetic characteristic...
2017, 35(6): 508-511,558.
doi: 10.3969/j.issn.1006-0111.2017.06.007
Abstract:
Objective To establish a HPLC method for the assay of sinoporphyrin sodium (DVDMS) in tumor-bearing mouse plasma and to study its pharmacokinetics. Methods The column was Waters XBridge C18 (3.0 mm×100 mm, 3.5 μm). Gradient elution was applied with...
Objective To establish a HPLC method for the assay of sinoporphyrin sodium (DVDMS) in tumor-bearing mouse plasma and to study its pharmacokinetics. Methods The column was Waters XBridge C18 (3.0 mm×100 mm, 3.5 μm). Gradient elution was applied with...
2017, 35(6): 512-515.
doi: 10.3969/j.issn.1006-0111.2017.06.008
Abstract:
Objective To investigate the effect of 5-FU on the expression of SHP2 gene in colorectal cancer cells RKO. Methods The human colorectal cancer cell line RKO of logarithmic growth phase was cultured 48 h with 5-FU. The expression of SHP2 was observe...
Objective To investigate the effect of 5-FU on the expression of SHP2 gene in colorectal cancer cells RKO. Methods The human colorectal cancer cell line RKO of logarithmic growth phase was cultured 48 h with 5-FU. The expression of SHP2 was observe...
2017, 35(6): 516-519,529.
doi: 10.3969/j.issn.1006-0111.2017.06.009
Abstract:
Objective To investigate the inhibitory effect of Xiaoaiping injection (XAP) combined with paclitaxel (PTX) on human ovarian cancer SK-OV-3 cells. Methods In vitro anti-proliferation activity study of XAP combined with PTX on human ovarian cancer S...
Objective To investigate the inhibitory effect of Xiaoaiping injection (XAP) combined with paclitaxel (PTX) on human ovarian cancer SK-OV-3 cells. Methods In vitro anti-proliferation activity study of XAP combined with PTX on human ovarian cancer S...
2017, 35(6): 520-525.
doi: 10.3969/j.issn.1006-0111.2017.06.010
Abstract:
Objective To study the conditions for isolating and purifying lignans in schisandra chinensis (Turcz) Baill by AB-8 type of macroporous adsorption resin. Methods The content of Schizandrol, Deoxyschizandrin, r-Schisandrin was determined by HPLC. Th...
Objective To study the conditions for isolating and purifying lignans in schisandra chinensis (Turcz) Baill by AB-8 type of macroporous adsorption resin. Methods The content of Schizandrol, Deoxyschizandrin, r-Schisandrin was determined by HPLC. Th...
2017, 35(6): 526-529.
doi: 10.3969/j.issn.1006-0111.2017.06.011
Abstract:
Objective To compare the changes of four flavonoid glycosides in the leaves of Hippophae rhamnoides L. before and after fermentation. Methods The water extract of Hippophae rhamnoides L. leaves and its fermented tea were concentrated and desiccated...
Objective To compare the changes of four flavonoid glycosides in the leaves of Hippophae rhamnoides L. before and after fermentation. Methods The water extract of Hippophae rhamnoides L. leaves and its fermented tea were concentrated and desiccated...
2017, 35(6): 530-534.
doi: 10.3969/j.issn.1006-0111.2017.06.012
Abstract:
Objective To establish the quality control methods for Qihuang Fuzheng particle. Methods Astragali Radix, Rehmanniae Radix Praeparata, Corni Fructus, Chuanxiong Rhizoma, Angelicae Sinensis Radix, Paeoniae Radix Rubra, Moutan Cortex, and Ophiopogoni...
Objective To establish the quality control methods for Qihuang Fuzheng particle. Methods Astragali Radix, Rehmanniae Radix Praeparata, Corni Fructus, Chuanxiong Rhizoma, Angelicae Sinensis Radix, Paeoniae Radix Rubra, Moutan Cortex, and Ophiopogoni...
2017, 35(6): 535-538,550.
doi: 10.3969/j.issn.1006-0111.2017.06.013
Abstract:
Objective To prepare compound ketoconazole ointment and perform the stability study. Methods Ketoconazole, mupirocin and mometasone furoate were used as active pharmaceutical ingredients (API). PEG mixture was used as matrix to prepare the ointment...
Objective To prepare compound ketoconazole ointment and perform the stability study. Methods Ketoconazole, mupirocin and mometasone furoate were used as active pharmaceutical ingredients (API). PEG mixture was used as matrix to prepare the ointment...
2017, 35(6): 539-542.
doi: 10.3969/j.issn.1006-0111.2017.06.014
Abstract:
Objective To establish quality standards for Kangkeling mixture. Methods Ardisiae Japonicae Herba, Stemonae Radix were identified by TLC. The content of bergenin was determined by HPLC. Lichrospher C18 column(5 μm,4.6 mm×250 mm)was used with methan...
Objective To establish quality standards for Kangkeling mixture. Methods Ardisiae Japonicae Herba, Stemonae Radix were identified by TLC. The content of bergenin was determined by HPLC. Lichrospher C18 column(5 μm,4.6 mm×250 mm)was used with methan...
2017, 35(6): 543-546.
doi: 10.3969/j.issn.1006-0111.2017.06.015
Abstract:
Objective To establish a quality standard for compound Heishen granules. Methods Scrophulariae Radix and Belamcandae Rhizoma were identified by TLC.HPLC was used to determine the content of cinnamic acid,tectoridin and irisflorentin.The HPLC was pe...
Objective To establish a quality standard for compound Heishen granules. Methods Scrophulariae Radix and Belamcandae Rhizoma were identified by TLC.HPLC was used to determine the content of cinnamic acid,tectoridin and irisflorentin.The HPLC was pe...
2017, 35(6): 547-550.
doi: 10.3969/j.issn.1006-0111.2017.06.016
Abstract:
Objective To establish a method for the determination of the total flavonoids content in compound Yinchen mixture by UV spectrophotometry. Methods Using rutin as comparison, three coloration methods were studied to find the optimal assay method. Re...
Objective To establish a method for the determination of the total flavonoids content in compound Yinchen mixture by UV spectrophotometry. Methods Using rutin as comparison, three coloration methods were studied to find the optimal assay method. Re...
2017, 35(6): 551-553,576.
doi: 10.3969/j.issn.1006-0111.2017.06.017
Abstract:
Objective To establish a HPLC method for simultaneously determining the content of dexamethasone acetate, camphor and phenol in compound cream. Methods The separation was performed on a SHIADZU-GL Inertsil® ODS-3 RP C18 analytical column with the m...
Objective To establish a HPLC method for simultaneously determining the content of dexamethasone acetate, camphor and phenol in compound cream. Methods The separation was performed on a SHIADZU-GL Inertsil® ODS-3 RP C18 analytical column with the m...
2017, 35(6): 554-558.
doi: 10.3969/j.issn.1006-0111.2017.06.018
Abstract:
Objective To design individualized anti-infective therapy for a critically ill patient. Methods Based on pathophysiological conditions and therapeutic drug levels,clinical pharmacists assisted physicians to optimize individual anti-infective medica...
Objective To design individualized anti-infective therapy for a critically ill patient. Methods Based on pathophysiological conditions and therapeutic drug levels,clinical pharmacists assisted physicians to optimize individual anti-infective medica...
2017, 35(6): 559-561.
doi: 10.3969/j.issn.1006-0111.2017.06.019
Abstract:
Objective In order to provide a reference for optimizing the dosage regimen of carbamazepine and valproate in pediatric epilepsy patients. Methods Pharmacist consulted one pediatric epilepsy patient with traumatic brain injury for post operation ep...
Objective In order to provide a reference for optimizing the dosage regimen of carbamazepine and valproate in pediatric epilepsy patients. Methods Pharmacist consulted one pediatric epilepsy patient with traumatic brain injury for post operation ep...
2017, 35(6): 562-564,568.
doi: 10.3969/j.issn.1006-0111.2017.06.020
Abstract:
Objective To analyze the effect of leukotriene receptor antagonist on anti-inflammation and immune function in asthmatic patients. Methods 86 cases of asthma patients in our hospital from August to December 2014 were taken as the research objects, ...
Objective To analyze the effect of leukotriene receptor antagonist on anti-inflammation and immune function in asthmatic patients. Methods 86 cases of asthma patients in our hospital from August to December 2014 were taken as the research objects, ...
2017, 35(6): 565-568.
doi: 10.3969/j.issn.1006-0111.2017.06.021
Abstract:
Objective To explore the breakthrough points of pharmaceutical care by clinical pharmacists for patients with heat stroke. Methods Clinical pharmacists participated in the treatment of patients with heat stroke, focused on the key points of effecti...
Objective To explore the breakthrough points of pharmaceutical care by clinical pharmacists for patients with heat stroke. Methods Clinical pharmacists participated in the treatment of patients with heat stroke, focused on the key points of effecti...
2017, 35(6): 569-572.
doi: 10.3969/j.issn.1006-0111.2017.06.022
Abstract:
The clinical practice of pharmacogenomics promotes the development of precision medicine. From the perspective of a pharmacist, the author analyzed the leading roles and specific responsibilities of pharmacists in pharmacogenomics, discussed the chal...
The clinical practice of pharmacogenomics promotes the development of precision medicine. From the perspective of a pharmacist, the author analyzed the leading roles and specific responsibilities of pharmacists in pharmacogenomics, discussed the chal...
2017, 35(6): 573-576.
doi: 10.3969/j.issn.1006-0111.2017.06.023
Abstract:
Objective To investigate the usage of intravenous infusion and the antibiotic intravenous infusion in different hospitals nationwide, and to evaluate the influence of the hospital bed number, hospital area and hospital grade on the clinical applicat...
Objective To investigate the usage of intravenous infusion and the antibiotic intravenous infusion in different hospitals nationwide, and to evaluate the influence of the hospital bed number, hospital area and hospital grade on the clinical applicat...
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