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2011 Vol. 29, No. 6

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Review of chemical constituents, pharmacological effects and clinical practices of Paederia scandens (Lour.) Merr.
XU Jin-long, LIU Lei, ZHANG Qiao-yan, QIN Lu-ping
2011, 29(6): 401-404.
Abstract(4297)
Abstract:
Paederia scandens (Lour.) Merri., a climbing plant, belonging to the family Rubiaceae, was a commonly used herbal medicine in folklore medicine. The chemical constituents of Paederia scandens were mainly flavonoids, iridoid glycosides and volatile oi...
Effects of opioids on MACBAR of inhalational anesthetics
LIU Zheng, CAI Guo-jun
2011, 29(6): 405-407,448.
Abstract(3415)
Abstract:
In recent years, great achievements had been made in flexibility and controllability of combination of inhalational anesthetics with intravenous drugs for balanced anesthesia. Clinical literature of combined use of opioids and inhalational anesthetic...
Review of the analysis methods of iodine in biological matrix
CUI Li-jun, FAN Guo-rong, LIAO Yue-hua
2011, 29(6): 408-411,415.
Abstract(3227)
Abstract:
Iodine was one of the most important trace elements in human nutrition. It was essential for the biosynthesis of thyroid hormones, which was closely related with the mental development, growth and basic metabolism. Iodine spead and exist widely in ma...
Progress of domestic Ervatamia Stapf
ZHU Zhi-xiang, CHEN Hai-sheng
2011, 29(6): 412-415.
Abstract(3121)
Abstract:
In recent years, Ervatamia genus plants contained indole alkaloids which had been proved to have good biological activity, had attracted more and more scholars' attention. Research reports in this area had been increasing annually. Many research prog...
Progress on the clinical application of traditional Chinese medicine in treatment of rheumatoid arthritis
ZHAO Ling, HU Yao-hua, LIU Run-hui, ZHANG Wei-dong, ZHENG Yi-nan, LIU Wen-cong
2011, 29(6): 416-420,425.
Abstract(3938)
Abstract:
Objective Rheumatoid arthritis (RA) was a systemic autoimmune disease, and known to cause continuous pain, recurrent process, and high rate of disability. It was a kind of diseases which was difficult to cure. Currently, the drug treatment, such as, ...
Advances in terpene trilactones of Ginkgo leaves
LIU Bin-guo, ZHANG Xin-ping, LIU Yan
2011, 29(6): 421-425.
Abstract(3888)
Abstract:
Of all the compound classes present in G. biloba, the terpene trilactones had received the most attention. The ginkgolides and bilobalide were selective platelet-activating factor antagonists and widely applied in the illness of blood vessel of heart...
Synthesis and antifungal activity of the novel triazole compounds
WANG Shu-dong, CHEN Xing-dong, ZHAO Qing-jie, ZOU Yan, HU Hong-gang, YU Shi-chong, WANG Ting, CHAI Xiao-yun, REN Hai-xiang
2011, 29(6): 426-430.
Abstract(3435)
Abstract:
Objective To design the synthesis and evaluate the antifungal active of the novel triazole compounds based on the structure of fluconazole. Methods The big N,N-disubstituted group was introduced and a series of compounds were synthesized, all of them...
Experimental study on hemostasis effect of carbonized hair
ZHU Yuan-yuan, QIU Yan, LU Yi, LIU Mei, LIU Jing
2011, 29(6): 431-434.
Abstract(3185)
Abstract:
Objective To observe the hemostasis effect of carbonized hair. Methods The coagulation time was measured in vitro with blood collected from rabbits in the presence of blank, starch, carbonized hair or Yunnan White Drug-Powder respectively. Bama minia...
Analysis on chemical constituents of ershen pill by HPLC-TOF/MS
JI Song-gang, WU Hai-tang, MIAO Hua-yan, WU Si, LI Xiang
2011, 29(6): 435-438.
Abstract(3979)
Abstract:
Objective To analyze chemical constituents of ershen pill by rapid-resolution(high performance) liquid chromatography-time of flight mass spectrometry (HPLC-TOF/MS). Methods A shelloseido column(3.0 mm×100 mm,3 μm) was used to separate. The mobile ph...
Protective effect of different source of Dendrobii Caulis on ischemic injury in SH-SY5Y cells
ZHANG Shu, CHEN Ya-lin, LUAN Jie, BIAN Xiao-lan, WANG Jia-chun
2011, 29(6): 439-441.
Abstract(3601)
Abstract:
Objective To study the protective effects of planting Dendrobii caulis and tissue culture planting Dendrobium officinale Kimura et Migo on glutamate damage induced in cultured SH-SY5Y cells. Methods The sera were obtained from rats by using the serum...
Studies on thermal stability of total alkaloids in rhynchophylline
LIU Wei, YANG Xue-ping, WANG Zhong-shi, WANG Meng, ZHANG Qiang, HAO Li-yong
2011, 29(6): 442-444.
Abstract(3258)
Abstract:
Objective To investigate the effect of heating on total alkaloids in rhynchphylla. Methods HPLC was employed to determine rhynchophylline and isorhynchophylline in total alkaloids among various conditions. Results Comparing with rhynchophylline, isor...
Analysis of the essential oil from two varieties of epimediums by GC-MS
SHI Qi-hong, LV Lei, LI Ling, ZHAO Liang, ZHANG Guo-qing
2011, 29(6): 445-448.
Abstract(2947)
Abstract:
Objective To analyze the chemical components of the essential oil from Epimedium pubescens Maxim.and Epimedium koreanum Nakai. by GC-MS. Methods The essential oil was extracted from two epimediums by steam distillation, the chemical components of the...
Clinical observation of the role of gabexate mesylate in treatment of choledocholithiasis
CHEN Wei-chen, XUE Bin, LI Zhi-chen
2011, 29(6): 449-450.
Abstract(3008)
Abstract:
Objective To confirm the effect of gabexate mesylate on eliminating choledocholithiasis. Methods By simple randomization, the patients were assigned control group (not use gabexate), regular dosage group and high dosage group. The difference between ...
Classification and clinical application of traditional Chinese medicine and natural medicine preparations for coronary heart disease
SU Jie, GONG Rui-lin
2011, 29(6): 451-452,477.
Abstract(2980)
Abstract:
Objective To classify traditional Chinese medicine and natural medicine preparations commonly used in clinical treatment of coronary heart disease and provide references to choice the reasonable treatment medicines. Methods Documents related books an...
Optimization of synthetic process of bendamustin
CAI Zhan, JIANG Zhi-hui, ZHAO Ming-zhu, ZHANG Da-zhi, ZANG Cheng-xu, HUANG Jing-hua
2011, 29(6): 453-454.
Abstract(3979)
Abstract:
Objective To optimize the synthetic process of bendamustin for high purity. Methods Bendamustin was prepared from 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester by reduction,substitution,hydrolization and salification,successively. Res...
Synthesis of monastrol catalyzed by 1-butyl-3-methylimidazolium (L)-camphorsulfonate
YUAN Wen-lin, XIA Tian-yi, SHEN Song-zhang, WANG Xiao-yan, HE Bang-ping, SUN Qing-yan
2011, 29(6): 455-456,459.
Abstract(3620)
Abstract:
Objective To explore a convenient and environmentally friendly benign synthesis method of monastrol. Methods Monastrol was synthesized from m-hydroxybenzaldehyde, ethyl acetoacetate and thiourea through the Biginelli reaction catalyzed by 1-butyl-3-m...
Determination of forbidden addition drugs of Diazepam,Clonazepam and Estazolam in tranquilizing mind traditional Chinese medicine by UPLC-MS/MS
CHEN Rui, CHU Zhong-ying, ZHANG Ji-chun, TIAN Lan
2011, 29(6): 457-459.
Abstract(3824)
Abstract:
Objective To establish a specific method for determination of forbidden addition drugs of Diazepam,Clonazepan and Estazolam in tranquilizing mind Traditional Chinese Medicine. Methods Diazepam, Clonazepam and Estazolam were determined and analyzed by...
Determination of chlorogenic acid content in wujin capsule by RP-HPLC
FEI Yang, WANG Hui, LING Shui-hua, ZHANG Guo-qing, ZHANG Zu-yan
2011, 29(6): 460-461.
Abstract(3020)
Abstract:
Objective To establish a RP-HPLC method for determination of chlorogenic acid in wujing capsule. Methods Agilent extend-C18 (4.6 mm×250 mm,5 μm)column was used. The mobile phase was acetonitrile: 0.1%formic acid (8:92). The flow rate was 1.0 ml/min, ...
Simulation of acid base titration process by computer
LI Yi-ming, CAO Yan, LIU Hong-ming, HUANG Chong-zhen, WANG Dong, ZHU Zhen-yu
2011, 29(6): 462-463,480.
Abstract(3004)
Abstract:
Acid base titration was a common type of volumetric analysis, which was difficult to calculate the pH value of the mixture solution and draw the titration curve. The formulas for percentage of titration (φ ) and concentration of H+ based on the acid ...
Application of servqual assessment in quality of pharmaceutical services for outpatients
CHENG Min-yu, CHEN Guo-yun
2011, 29(6): 464-466.
Abstract(3557)
Abstract:
Objective To explore the application of servqual method in quality assessment of pharmaceutical services for outpatients, and investigate the main problems in the pharmaceutical services. Methods The servqual table was designed, and used as a questio...
Requirements and thinkings of hospital pharmacists under the new situation
GENG Xin-hui, ZHANG Mei-ling, BIAN Yan-fang, CAI Zhen
2011, 29(6): 467-469.
Abstract(2965)
Abstract:
To analyze the more specific and stricter requirements of the public for hospital pharmacists under new healthcare reform. The gap between the current situation and realistic requirements of hospital pharmacists was discussed. In addition, a way was ...
Establishment of quality target assessment of drug supply center in our hospital
YANG Xiao-min, TANG Li-hua, YUAN Jin
2011, 29(6): 470-471,474.
Abstract(2877)
Abstract:
Objective To approach the methods for improving the rate of drugs consistent with the account book, rate of drugs turnover and ensure timely supply of drugs in hospital pharmacy. Methods SO9001 quality management system concept and single-species man...
Statistical analysis of papers from school of Pharmacy in Second Military Medical University in journals covered by SCIE from 1994 to 2009
LIU Yi-qing, HUANG Xiao-bo, LU Min, ZHANG Hong-wu
2011, 29(6): 472-474.
Abstract(3001)
Abstract:
Objective To perform a bibliometric analysis of paper published by school of Pharmacy in Second Military Medical University in journals covered by SCIE during 1994~2009,so as to provide evidence for decision making in scientific research administrati...
Cost-effectiveness analysis of three kinds of nucleoside analogues for chronic hepatitis B
LIN Jing-shi
2011, 29(6): 475-477.
Abstract(3308)
Abstract:
Objective To investigate economic effects of three kinds of nucleoside analogues in treatment of chronic hepatitis B. Methods 268 cases were divided into three groups, ADV group with adefovir dipivoxil 10mg, ETV group with entecavir 0.5 mg, LdT group...
Discussion of the quantity of random testing in military drug
QIE Ge-hong, ZHANG Xiao-dong, JIANG Yu
2011, 29(6): 478-480.
Abstract(3073)
Abstract:
In order to ensure the safety of drug usage among troops, the Military Drug Control Institute was responsible for all the sampling inspection on military drug and pharmaceutical preparation. However, problems kept coming out during the reform attempt...