2012 Vol. 30, No. 1
Display Method:
2012, 30(1): 1-3,13.
doi: 10.3969/j.issn.1006-0111.2012.01.001
Abstract:
The IPSC technology, which was discovered in 2006, had drawn much attention among laboratories around the world and become a new milestone in the life science. The history of pluripotency study, with an emphasis on the culturing technology of IPSC an...
The IPSC technology, which was discovered in 2006, had drawn much attention among laboratories around the world and become a new milestone in the life science. The history of pluripotency study, with an emphasis on the culturing technology of IPSC an...
2012, 30(1): 4-7,57.
doi: 10.3969/j.issn.1006-0111.2012.01.002
Abstract:
Both the stealth and targeting features were important for effective and selective drug delivery to the tumors.However, it was difficult to achieve both features simultaneously. Some of the novel targeting strategies had the potential to overcome thi...
Both the stealth and targeting features were important for effective and selective drug delivery to the tumors.However, it was difficult to achieve both features simultaneously. Some of the novel targeting strategies had the potential to overcome thi...
2012, 30(1): 8-13.
doi: 10.3969/j.issn.1006-0111.2012.01.003
Abstract:
Objective To review the chemical and pharmacological study of the C6-C3 compounds from genus Illicium and provide the reference for further development of genus Illicium. Methods Relevant literatures of C6-C3 compounds in genus Illicium were searched...
Objective To review the chemical and pharmacological study of the C6-C3 compounds from genus Illicium and provide the reference for further development of genus Illicium. Methods Relevant literatures of C6-C3 compounds in genus Illicium were searched...
2012, 30(1): 14-18,37.
doi: 10.3969/j.issn.1006-0111.2012.01.004
Abstract:
Peptide analog of hypoglycemic drugs had a normal physiological function of insulin secretion. The hypoglycemic effect of peptide depended on blood glucose levels of patients, which induced very few incidents of hypoglycemia. Peptides of sustained an...
Peptide analog of hypoglycemic drugs had a normal physiological function of insulin secretion. The hypoglycemic effect of peptide depended on blood glucose levels of patients, which induced very few incidents of hypoglycemia. Peptides of sustained an...
2012, 30(1): 19-24,41.
doi: 10.3969/j.issn.1006-0111.2012.01.005
Abstract:
The small organic molecules catalyst was a hotspot in asymmetric synthesis. Due to the excellent enantiselectivity of proline in many asymmetric reactions, people showed great interest in the modification of it, which aimed to get better organocataly...
The small organic molecules catalyst was a hotspot in asymmetric synthesis. Due to the excellent enantiselectivity of proline in many asymmetric reactions, people showed great interest in the modification of it, which aimed to get better organocataly...
2012, 30(1): 25-28,31.
doi: 10.3969/j.issn.1006-0111.2012.01.006
Abstract:
Objective To investigate the protect effect and mechanism of total polysaccharides (TPC) isolated from 50% ethanol extract of Wuzi-Yanzong pill (WZ) against chronic alcohol-induced injury in Rat . Methods The effect of TPC on chronic ethanol hepatoto...
Objective To investigate the protect effect and mechanism of total polysaccharides (TPC) isolated from 50% ethanol extract of Wuzi-Yanzong pill (WZ) against chronic alcohol-induced injury in Rat . Methods The effect of TPC on chronic ethanol hepatoto...
2012, 30(1): 29-31.
doi: 10.3969/j.issn.1006-0111.2012.01.007
Abstract:
Objective To develop a fast reverse-phase high-performance liquid chromatography assay method for the determination of ambroxol hydrochloride. Methods A Diamonsil-C18(200 mm×4.6 mm,5μm)column was used.The mobile phase consisted of methanol-0.01 mol/L...
Objective To develop a fast reverse-phase high-performance liquid chromatography assay method for the determination of ambroxol hydrochloride. Methods A Diamonsil-C18(200 mm×4.6 mm,5μm)column was used.The mobile phase consisted of methanol-0.01 mol/L...
2012, 30(1): 32-34.
doi: 10.3969/j.issn.1006-0111.2012.01.008
Abstract:
Objective To study the preparation method of quercetin liposome and screen the optimal technological conditions by the particle sizes and the encapsulation efficiencies of quercetin. Method Liposomes were made of hydrogenated soybean phosphatidylchol...
Objective To study the preparation method of quercetin liposome and screen the optimal technological conditions by the particle sizes and the encapsulation efficiencies of quercetin. Method Liposomes were made of hydrogenated soybean phosphatidylchol...
2012, 30(1): 35-37.
doi: 10.3969/j.issn.1006-0111.2012.01.009
Abstract:
Objective To optimize the synthesis of substituted tetrahydronaphthalene and investigate the influence of 10% Pd/C catalyst in the synthesis of key intermediate. Methods A parallel test was carried out to compare the catalytic activity of triethyl si...
Objective To optimize the synthesis of substituted tetrahydronaphthalene and investigate the influence of 10% Pd/C catalyst in the synthesis of key intermediate. Methods A parallel test was carried out to compare the catalytic activity of triethyl si...
2012, 30(1): 38-41.
doi: 10.3969/j.issn.1006-0111.2012.01.010
Abstract:
Objective To investigate the preparation method, the structure and the sun protection factor (SPF) of the polyelectrolyte self-assembled microcapsules containing TiO2 nanoparticles. Methods Calcium carbonate was used as the core, and the semipermeabl...
Objective To investigate the preparation method, the structure and the sun protection factor (SPF) of the polyelectrolyte self-assembled microcapsules containing TiO2 nanoparticles. Methods Calcium carbonate was used as the core, and the semipermeabl...
2012, 30(1): 42-44,48.
doi: 10.3969/j.issn.1006-0111.2012.01.011
Abstract:
Objective To establish a method for determination of (E)-3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl) methoxy)phenyl)acrylate in plasma of SD rats by RP-HPLC. Methods The chromatographic separation was performed on a Diamonsil-C18 column(100 mm×4.6 ...
Objective To establish a method for determination of (E)-3-(3-methoxy-4-((3,5,6-trimethylpyrazin-2-yl) methoxy)phenyl)acrylate in plasma of SD rats by RP-HPLC. Methods The chromatographic separation was performed on a Diamonsil-C18 column(100 mm×4.6 ...
2012, 30(1): 45-48.
doi: 10.3969/j.issn.1006-0111.2012.01.012
Abstract:
Objective To establish a LC-MS/MS method for determination of polydatin concentration in rats plasma. Methods The plasma concentration of polydatin was determined by LC-MS/MS. Using stilbene glucoside as internal standard, after precipitation of the ...
Objective To establish a LC-MS/MS method for determination of polydatin concentration in rats plasma. Methods The plasma concentration of polydatin was determined by LC-MS/MS. Using stilbene glucoside as internal standard, after precipitation of the ...
2012, 30(1): 49-51,63.
doi: 10.3969/j.issn.1006-0111.2012.01.013
Abstract:
Objective To establish a HPLC method to determine the content and related substance of rosiglitazone hydrochloride tablets. Methods The analysis was achieved on a Diamonsil C18 column(250 mm×4.6 mm, 5 μm) using a mobile phase of 0.025 mol/L ammonium ...
Objective To establish a HPLC method to determine the content and related substance of rosiglitazone hydrochloride tablets. Methods The analysis was achieved on a Diamonsil C18 column(250 mm×4.6 mm, 5 μm) using a mobile phase of 0.025 mol/L ammonium ...
2012, 30(1): 52-54.
doi: 10.3969/j.issn.1006-0111.2012.01.014
Abstract:
Objective To establish a HPLC-MS/MS method for determination of sodium Danshensu in SD rat liver. Methods Tissue samples were pretreated by liquid-liquid extraction method after homogenate, and ketoprofen was used as the internal standard. Analytical...
Objective To establish a HPLC-MS/MS method for determination of sodium Danshensu in SD rat liver. Methods Tissue samples were pretreated by liquid-liquid extraction method after homogenate, and ketoprofen was used as the internal standard. Analytical...
2012, 30(1): 55-57.
doi: 10.3969/j.issn.1006-0111.2012.01.015
Abstract:
Objective To investigate the effect of combination of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy. Methods 323 patients with diabetic nephropathy were randomly divided into 2 groups. Group I (Compound chuanqiong ...
Objective To investigate the effect of combination of Compound Chuanqiong capsules and irbesartan in patients with diabetic nephropathy. Methods 323 patients with diabetic nephropathy were randomly divided into 2 groups. Group I (Compound chuanqiong ...
2012, 30(1): 58-59.
doi: 10.3969/j.issn.1006-0111.2012.01.016
Abstract:
Objective To explore the application of moist burn ointment in skin injury caused by diarrhea in patients of ICU and solve the problems of perianal skin care in ICU diarrhea patients. Method According to the admission sequence,ICU patients was divide...
Objective To explore the application of moist burn ointment in skin injury caused by diarrhea in patients of ICU and solve the problems of perianal skin care in ICU diarrhea patients. Method According to the admission sequence,ICU patients was divide...
2012, 30(1): 60-60,66.
doi: 10.3969/j.issn.1006-0111.2012.01.017
Abstract:
Objective Summary Batroxobin injection combined Ginkgo biloba extract and dipyridamole injection efficacy of treatment of sudden deafness,Treatment of sudden deafness of effective drug. Method Selected 108 cases (120 ears) in patients with sudden dea...
Objective Summary Batroxobin injection combined Ginkgo biloba extract and dipyridamole injection efficacy of treatment of sudden deafness,Treatment of sudden deafness of effective drug. Method Selected 108 cases (120 ears) in patients with sudden dea...
2012, 30(1): 61-63.
doi: 10.3969/j.issn.1006-0111.2012.01.018
Abstract:
Objective To Sum up the situation of using antibiotics in intracoronary coronary stenting, and normalize the usage criterion and reinforce the management of antibiotics. Methods Retrospective survey method was used. 206 cases of patients who underwen...
Objective To Sum up the situation of using antibiotics in intracoronary coronary stenting, and normalize the usage criterion and reinforce the management of antibiotics. Methods Retrospective survey method was used. 206 cases of patients who underwen...
2012, 30(1): 64-66.
doi: 10.3969/j.issn.1006-0111.2012.01.019
Abstract:
Objective To evaluate the roles of the two indexes, defined single dose (DSD) and defined daily frequency (DDF), in the rational use of antimicrobial drugs in inpatients of respiratory department. Methods 20 percent of cases of respiratory department...
Objective To evaluate the roles of the two indexes, defined single dose (DSD) and defined daily frequency (DDF), in the rational use of antimicrobial drugs in inpatients of respiratory department. Methods 20 percent of cases of respiratory department...
2012, 30(1): 67-69,77.
doi: 10.3969/j.issn.1006-0111.2012.01.020
Abstract:
Objective To grasp the domestic hospitals in the present situation of the pharmacy trusteeship,and explore the model of separation of prescribing and dispensing. Methods The advantages and disadvantages of the hospital pharmacy trusteeship were analy...
Objective To grasp the domestic hospitals in the present situation of the pharmacy trusteeship,and explore the model of separation of prescribing and dispensing. Methods The advantages and disadvantages of the hospital pharmacy trusteeship were analy...
2012, 30(1): 70-72.
doi: 10.3969/j.issn.1006-0111.2012.01.021
Abstract:
Objective To analyze the prescriptions of drug return and explore the reason and treatment of drug return phenomenon from outpatient pharmacy. To propose appropriate countermeasures to reduce the incidence of drug return and promote rational drug use...
Objective To analyze the prescriptions of drug return and explore the reason and treatment of drug return phenomenon from outpatient pharmacy. To propose appropriate countermeasures to reduce the incidence of drug return and promote rational drug use...
2012, 30(1): 73-74.
doi: 10.3969/j.issn.1006-0111.2012.01.023
Abstract:
Objective To reasonably control the drug inventory, and to improve the efficiency of drug inventory management through investigating the scientific management mode of drug stock. Method The drug classification management methods were used to decrease...
Objective To reasonably control the drug inventory, and to improve the efficiency of drug inventory management through investigating the scientific management mode of drug stock. Method The drug classification management methods were used to decrease...
2012, 30(1): 75-77.
doi: 10.3969/j.issn.1006-0111.2012.01.024
Abstract:
Objective To evaluate the value of PBL teaching method in the teaching of pharmaceutical theory. Methods The subjects of the research were the scores of 4-year undergraduates of pharmacy from Grade 2001 in Hubei medical college. Results 88.6% of the ...
Objective To evaluate the value of PBL teaching method in the teaching of pharmaceutical theory. Methods The subjects of the research were the scores of 4-year undergraduates of pharmacy from Grade 2001 in Hubei medical college. Results 88.6% of the ...
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