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2010 Vol. 28, No. 4

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Progress on research of ganoderma polysaccharides
XIANG Jun-yu, XU An, XIA Mao, ZHOU Ting-ting, FAN Guo-rong
2010, 28(4): 241-244.
Abstract(3149) PDF (617KB)(1609)
Abstract:
Ganoderma polysaccharides(GP) contain active substances with remarkable bioactivities such as immunoregulation,anticancer,anti-oxidant,anti-aging and promoting blood circulation by removing blood stasis.Their recent research progress is of great sign...
2010, 28(4): 245-247,295.
Abstract(2186) PDF (727KB)(1014)
Abstract:
2010, 28(4): 248-250,303.
Abstract(2641) PDF (217KB)(1232)
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2010, 28(4): 251-254,287.
Abstract(2364) PDF (248KB)(782)
Abstract:
Effect of a single dose of ALS3K on blood pressure in spontaneously hypertensive rats
SU Feng-yun, LIU Wei, WANG Wei, ZHANG Hao, LIU Ai-jun, SU Ding-feng
2010, 28(4): 255-257,290.
Abstract(3336) PDF (406KB)(544)
Abstract:
Objective To investigate the effect of a single dose of allisartan potassium(ALS3K) on the blood pressure(BP) in spontaneously hypertensive rats(SHR). Methods SHR were randomly divided into seven groups(n=9 per group) and given 0.5%CMC-Na,allisartan...
A nuclear magnetic resonance spectroscopic metabonomics analysis for serum samples of hypertension patients with hyperactivity of liver-yang
JIANG Hai-qiang, MA Bin, NIE Lei, LI Yun-lun
2010, 28(4): 258-261.
Abstract(2415) PDF (323KB)(490)
Abstract:
Objective To apply 1HNMR spectroscopic analysis and principal components analysis(PCA) for investigating the difference of blood composition spectrum between hypertension patients with hyperactivity of liver-yang and healthy volunteers,to search poss...
2010, 28(4): 261-261.
Abstract(2097) PDF (68KB)(554)
Abstract:
Different administrations of combination cytarabine or daunorubicin with all-trans retinoic acid lead to variance of HL-60''s apoptosis and respectively mechanism in vitro
ZHANG Chun, LU Xiao-tong, CHEN Min-ling, ZHANG Shun-guo, WANG Yan-qiong, ZHAO Wei, ZHANG Jian
2010, 28(4): 262-264,273.
Abstract(2537) PDF (254KB)(582)
Abstract:
Objective To investigate variance of apoptosis and correspondingly mechanism in HL-60 cell line in vitro by different combinations adminstration of three drug including cytarabine,daunorubicin and all-trans retinoic acid.Methonds HL-60 cell line was ...
Comparative study on extraction of essential oil from Cortex Moutan by steam distillation and ethyl ether ultrasonic
LIU Zhi-rui, LIU Wen-yong, WU Hao, Zhu Zhen-yu, CHAI Yi-feng
2010, 28(4): 265-266,270.
Abstract(2751) PDF (256KB)(740)
Abstract:
Objective To compare the difference of essential oil from Cortex Moutan extracted by different method. Methods Steam distillation and ethyl ehter ultrasonic were used to extract the essential oil from Cortex Moutan which were analyzed by GC-MS. Resu...
Study on the release in vitro of tacrolimus from the thermosensitive ophthalmic gel
ZHANG Jing, SONG Hong-tao, YANG Li-xia, ZHOU Xin
2010, 28(4): 267-270.
Abstract(2488) PDF (353KB)(628)
Abstract:
Objective To study the factors that influence the release of tacrolimus from the thermosensitive ophthalmic gel. Methods The non-membrane model was introduced to observe the influence on the drug release and gel erosion for surface area and shaking ...
Studies on the chemical constituents of Cirsium segestum
CAO Qin, CHEN Jian-tao
2010, 28(4): 271-273.
Abstract(3287) PDF (279KB)(753)
Abstract:
Objective To study the chemical constituents of Cirsium segestum. Methods Multi-chromatographic Methods including Silica gel column chromatography and Sephadex LH-20 gel permeation were employed for the isolation and purification.The structures were...
Bioactive constituents from Sinularia sp
MENG Li-yuan, LI Xiu-bao, ZHANG Wen, LI Ling, SUN Peng, TANG Hua, LIU Bao-shu, YI Yang-hua
2010, 28(4): 274-278.
Abstract(2527) PDF (428KB)(314)
Abstract:
Objective To study the bioactive constituents of soft coral Sinularia sp. Methods The compounds were isolated and purified by silica gel,Sephadex LH-20 column chromatography and HPLC.Their chemical structures were identified by spectroscopic analysi...
Protective effects of Danshensu on acute myocardial ischemia in rats
LU Wen-quan, ZHANG Guo-qiang, CHEN Da-gui, ZHANG Chuan
2010, 28(4): 279-282.
Abstract(2643) PDF (212KB)(568)
Abstract:
Objective To study the protective effects of Danshensu(Dan) on acute myocardial ischemia in rats. Methods Acute myocardial ischemia rats were induced by injection of Iso and Pit.The height changes of T wave in ECG were examined.The levels of LDH,CK ...
Study on the effect and mechanisms of timosaponin B-Ⅱ on antidepressant
LU Ming-zhu, ZHANG Zhi-qiang, YI Jia, CHEN Wan-sheng, HOU Zhong-hai, LI Tie-jun
2010, 28(4): 283-287.
Abstract(3042) PDF (275KB)(566)
Abstract:
Objective To study the effect and mechanisms of timosaponin B-Ⅱ on depression. Methods The tail suspension test(TST),forced swimming test(FST),open field activity test(OFA),APO-induced synergistic action test,inhibiting reuptake of monoamine neurotr...
Clinical study of tacrolimus ointment in the treatment of chronic hand eczema
WANG Qiu-feng, LI Li, XIA Ru-shan, JIANG Bin-bin, YANG Wei-ling
2010, 28(4): 288-290.
Abstract(3003) PDF (173KB)(1015)
Abstract:
Objective To evaluate the efficacy and safety of 0.1% tacrolimus ointment in the treatment of chronic hand eczema in patients. Methods A total of 86 patients with chronic hand eczema applied 0.1%tacrolimus ointment or hydrocortisone butyrate cream t...
Determination of total sugar and acidity in milk vetch honey
JIANG Chong-hui, YANG Jie
2010, 28(4): 291-292,307.
Abstract(2144) PDF (209KB)(399)
Abstract:
Objective To establish the method for the quantitative determination of total sugar and acidity in milk vetch honey. Methods Ultraviolet spectrophotometry was used to determine the content of total sugar in honey.Potentionmetric titration was used t...
Determination of adenosine in capsule of Chinese Caterpillar Fungus by HPLC
YAN Dong-lin
2010, 28(4): 293-295.
Abstract(2751) PDF (217KB)(1034)
Abstract:
Objective To establish a method for determination of adenosine in capsule of Chinese Caterpillar Fungus. Methods HPLC was carried out with Agilent TC-C18(4.6 mm × 250 mm,5 μm);the Mobile phase was acetonitrile-0.01 mol/L potassium dihydrogen phospha...
Design,synthesis of novel quinazolinon compounds as human anti-acrosin inhibitor
NING Wei-wei, LIU Xue-fei, ZHANG Xiao-meng, ZHENG Can-hui, SHENG Chun-quan, ZHOU You-jun, ZHANG Ling, LV Jia-guo, ZHU Ju
2010, 28(4): 296-298,312.
Abstract(3063) PDF (399KB)(467)
Abstract:
Objective Novel 3-substituted quinazolinon compounds were designed and synthesised on the base of the active site of human acrosin. Methods The compounds were designed by computer and chemically synthesised. Results Seven 3-substituted quinazolinon...
Studies on synthesis and antiviral activities of a novel acyclic nucleoside phosphonates analogues on HBV
QIU Xiao-min, LIU Jia, FENG Ji-lu, NIU Chun-juan, LI Ke
2010, 28(4): 299-303.
Abstract(2553) PDF (322KB)(413)
Abstract:
Objective To study of design and synthesis of the novel acyclic nucleoside phosphonates analogues and study their activities of inhibiting HBV. Methods Based on the chemical structure of PMEA,and according to the theory of bioisostere,a 8-aza-6-thio...
Analysis of typical cases in practice of prescription comment
ZHOU Xin, LI Hong-jie, LIU Rui-ning
2010, 28(4): 304-307.
Abstract(3982) PDF (210KB)(1166)
Abstract:
Objective To promote safe,effective,economical and proper medication by prescription comment. Methods From August 2007 to October 2008,100 outpatient prescriptions were spot-checked stochastically each month in our hospital which were statistically ...
2010, 28(4): 308-310.
Abstract(2429) PDF (157KB)(998)
Abstract:
2010, 28(4): 310-312.
Abstract(2578) PDF (441KB)(593)
Abstract:
Analysis of 87 ADR cases in our hospital in 2009
MA Ming-hua, YU Zi-cheng, QIU Jin, FU Zhe-tun
2010, 28(4): 313-315.
Abstract(2475) PDF (172KB)(648)
Abstract:
Objective To enhance the level of safe and rational use of drugs throgh investigating the adverse drug reactions(ADR) cases in our hospital in 2009. Methods 87 ADR cases in our hospital in 2009 were collected which were analyzed according to the pat...
2010, 28(4): 316-320.
Abstract(2076) PDF (315KB)(290)
Abstract: