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Volume 28 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2010  >  28(4): 279-282

LU Wen-quan, ZHANG Guo-qiang, CHEN Da-gui, ZHANG Chuan. Protective effects of Danshensu on acute myocardial ischemia in rats[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(4): 279-282.
Citation: LU Wen-quan, ZHANG Guo-qiang, CHEN Da-gui, ZHANG Chuan. Protective effects of Danshensu on acute myocardial ischemia in rats[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(4): 279-282.
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Protective effects of Danshensu on acute myocardial ischemia in rats

  • 1.

    Changzheng Hospital,Second Military Medical University,Shanghai 200433,China

  • 2.

    Section of Health,73841th Unit of PLA,Nanjing 210002,China

  • 3.

    School of pharmacy,Second Military Medical University,Shanghai 200433,China

  • Received Date: 2009-12-07
  • Rev Recd Date: 2010-01-05
  • Objective To study the protective effects of Danshensu(Dan) on acute myocardial ischemia in rats. Methods Acute myocardial ischemia rats were induced by injection of Iso and Pit.The height changes of T wave in ECG were examined.The levels of LDH,CK in serum were measured. Results Dan(6、12、24 mg/kg) can significantly inhibit the height changes of T wave,obviously decrease the level of LDH,CK in the serum. Conclusion The Results indicate that Dan has protective effects on acute myocardial ischemia in rats.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Protective effects of Danshensu on acute myocardial ischemia in rats

  • 1. Changzheng Hospital,Second Military Medical University,Shanghai 200433,China
  • 2. Section of Health,73841th Unit of PLA,Nanjing 210002,China
  • 3. School of pharmacy,Second Military Medical University,Shanghai 200433,China
  • Received Date: 2009-12-07
  • Rev Recd Date: 2010-01-05

Abstract: Objective To study the protective effects of Danshensu(Dan) on acute myocardial ischemia in rats. Methods Acute myocardial ischemia rats were induced by injection of Iso and Pit.The height changes of T wave in ECG were examined.The levels of LDH,CK in serum were measured. Results Dan(6、12、24 mg/kg) can significantly inhibit the height changes of T wave,obviously decrease the level of LDH,CK in the serum. Conclusion The Results indicate that Dan has protective effects on acute myocardial ischemia in rats.

LU Wen-quan, ZHANG Guo-qiang, CHEN Da-gui, ZHANG Chuan. Protective effects of Danshensu on acute myocardial ischemia in rats[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(4): 279-282.
Citation: LU Wen-quan, ZHANG Guo-qiang, CHEN Da-gui, ZHANG Chuan. Protective effects of Danshensu on acute myocardial ischemia in rats[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(4): 279-282.
shu

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