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2010 Vol. 28, No. 5

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2010, 28(5): 321-324.
Abstract(2555) PDF (530KB)(645)
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2010, 28(5): 325-327,338.
Abstract(2509) PDF (230KB)(1472)
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2010, 28(5): 328-330.
Abstract(2964) PDF (173KB)(1577)
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Study on pharmacokinetics of compound Danshen dropping pills of new matrix
Wang Wei, Wang Xiao-hua, Zhang Xiao-jie, Chen Jian-ming
2010, 28(5): 331-333.
Abstract(2705) PDF (204KB)(618)
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Objective To study the pharmacokinetics of compound Danshen dropping pills of new matrix. Methods HPLC was used as a detection method.New Zealand rabbits were taken as experimental animals.The compound Danshen dropping pills sold in market were tak...
Determination and structural elucidation of sesquiterpene lactones from Inula racemosa
HUO Yan, SHI Hai-ming, LI Wei-wei, GUO Cheng, LI Xiao-bo
2010, 28(5): 334-338.
Abstract(2571) PDF (390KB)(671)
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Objective To establish a method of HPLC for the simultaneous quantification of three sesquiterpene lactones in Inula racemosa. Methods Agilent Zorbax XDB-C18 column(250 mm×4.6 mm,5 μm) was uesed with a mobile phase consists of 55% acetonitrile and ...
Development of nimodipine solid dispersion
YANG Ling, ZHONG Yan-qiang
2010, 28(5): 339-341,344.
Abstract(2880) PDF (328KB)(1070)
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Objective To prepare Nimodipine solid dispersion and increase its dissolution rate.Methonds Using polyvinylpyrrolidone(PVP) as a carrier,nimodipine solid dispersion was prepared by spray-drying method.differential scanning calorimetry and X-Ray powd...
Determination of seven baleful trace elements in nine Chinese patent medicine treating diabetes mellitus
BAO Li-li, YU Kun, XUE Da-fang, LI Hong, TENG Wen-feng
2010, 28(5): 342-344.
Abstract(2325) PDF (176KB)(453)
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Objective To determine Pb,Cd,Hg,As,U,Th,Tl in nine clinical commonly used Chinese traditional medicine treating diabetes mellitus,which provide reference data for modern medication.Methonds The samples were treated by microwave digestion,and determi...
Synthesis of N-tert-butoxycarbonyl-DL-(±)-homo-tyrosine
LIU Hong-ming, QIN Ye, YAO Jian-zhong, SHENG Chun-quan, MIAO Zhen-yuan, ZHANG Wan-nian
2010, 28(5): 345-347,384.
Abstract(2387) PDF (288KB)(918)
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Objective To prepare N-tert-butoxycarbonyl-DL-(±)-homo-tyrosine(1),a key unusual amino acid and pharmaceutical intermediate for the total synthesis of novel peptides drug including cyclic or straight chain peptide. Methods Starting from L-aspartic ...
Effects of Protoveratrine A on cardiovascular and respiratory system in rats
ZHAO Yu, JIANG Hua, XI Gui-lin, LI Hui-linag, YUAN Bo-jun, LU Guo-cai, ZHANG Wei-dong
2010, 28(5): 348-351.
Abstract(2832) PDF (215KB)(506)
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Objective To observe the effects of Protoveratrine A(PA) on cardiovascular and respiratory system in rats. Methods The experimental rats(n=40,mf=1:1) were equally randomized into 4 groups: blank control group and groups of low dose(ig,0.25 mg/kg,s...
2010, 28(5): 351-351.
Abstract(2408) PDF (108KB)(292)
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Hepatoprotective effect of Shugananlening extract against acute hepatic injury in mice
XIA Ai-jun, ZHANG Qi, LIANG Yuan
2010, 28(5): 352-353,380.
Abstract(2824) PDF (177KB)(896)
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Objective To study the hepatoprotective effect of shugananlening extract against mice liver damage which induced by carbon tetrachloride(CCl4). Methods Acute chemical liver jnjury model was induced by CCl4 in mice.The activities of ALT,AST in serum...
Comparative study on promoting blood circulation to remove blood stasis function of different processed rhubarb products
ZHU Shi-ta, LI Xin-zhong, WEN Xiao-li, LEI Peng
2010, 28(5): 354-355,358.
Abstract(3292) PDF (181KB)(575)
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Objective To select four processed rhubarb products(i.e.,crude rhubarb,prepared rhubarb,rhubarb charcoal and rhubard stir-fried with wine) and to compare their function on promoting blood circulation to remove blood stasis. Methods The different fu...
The clinical observation of the analgesia effect and safety of Fentanyl Transdermal System for day surgery patients with anus surgeries
LU Xiao-fang, LI Qiong-zhen, ZHU Tao
2010, 28(5): 356-358.
Abstract(2580) PDF (182KB)(605)
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Objective To observe the analgesia effect and safety of Fentanyl Transdermal System and tramadol for day surgery patients with anus surgeries. Methods 120 cases of anus surgeries undergo spinal anesthesia were randomly divided into three groups.Pat...
2010, 28(5): 359-360.
Abstract(2154) PDF (128KB)(385)
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Chemical stability of cyclophosphamide in glass bottle and PVC infusion bags
WANG Yan-qiong, ZHANG Shun-guo, Xu Tiao, CHEN Ming-lin, GUO Xiao-wen
2010, 28(5): 361-362.
Abstract(2625) PDF (134KB)(401)
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Objective To investigate chemical stability of cyclophosphamid in glass bottles and PVC infusion bags. Methods Cyclophosphamide was dissolved with 0.9% sodium chloride respectively in glass bottles and PVC bags.The storage condition for the solutio...
The pharmacokinetics study of tinidazole pectin matrics colon-specific sustained-release tablets in dogs
LIU Fu-qiang, WANG Yan-ping, ZHAO Nan, WANG Xiang-yang, CUI Hai-zhen
2010, 28(5): 363-365,368.
Abstract(2778) PDF (328KB)(348)
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Objective To develop a method to study the pharmacokinetics of tinidazole pectin matrics colon-specific sustained-release tablets in dogs. Methods The plasma concentrations were determined by HPLC.Two-period cross over self-control trail was conduc...
Improvement of preparation and the stability of furacillin solution
LI Zhi-yuan, WANG Xin-hong, LIU Gui-gang, YAN Qiong
2010, 28(5): 366-368.
Abstract(2562) PDF (165KB)(531)
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Objective To improve the preparation method for furacillin solution and observe the stability of the solution. Methods The original preparation technics was modified.The furacillin solution was qualitatively analyzed by observation and quantitative...
Study on in vitro release and correlation between in vivo and in vivo of thienorphine hydrochloride microspheres
YANG Yang, GAO Yong-liang
2010, 28(5): 369-371,382.
Abstract(2547) PDF (368KB)(350)
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Objective To establish a method for the determination of in vitro release of thienorphine hydrochloride micro-spheres with a good correlation between in vivo and in vitro. Methods Immediate release and dialysis release Methods were used to determin...
Content determination of carbamazepine tablet by liquid chromatographic tandem mass spectrometry
XIE Hua, WANG Rong, JIA Zheng-ping, ZHANG Juan-hong
2010, 28(5): 372-373,395.
Abstract(2321) PDF (300KB)(793)
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Objective To develop liquid chromatography with tandem mass spectrometry(LC-MS/MS) detection for the content determination of carbamazepine tablet. Methods The method was used.The sample was analyzed on Zorbax Extend-C18(150 mm×4.6 mm,5 μm),with mo...
Analysis on utilization of anti-infection drugs in our hospital between 2007 and 2009
YANG A-jing, YANG Ning, ZHANG Juan
2010, 28(5): 374-377.
Abstract(2558) PDF (233KB)(198)
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Objective To provide evidences for clinical rational use and scientific management of the anti-infection drugs through investigating the application status of the anti-infection drugs in our hospital. Methods Utilization of anti-infection drugs was...
2010, 28(5): 378-380.
Abstract(1855) PDF (167KB)(201)
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2010, 28(5): 381-382.
Abstract(1883) PDF (176KB)(518)
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2010, 28(5): 383-384.
Abstract(2397) PDF (124KB)(338)
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2010, 28(5): 385-386,400.
Abstract(2342) PDF (168KB)(245)
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2010, 28(5): 387-389.
Abstract(2038) PDF (187KB)(643)
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2010, 28(5): 390-392.
Abstract(1774) PDF (175KB)(589)
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2010, 28(5): 393-395.
Abstract(2274) PDF (173KB)(308)
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2010, 28(5): 396-400.
Abstract(2114) PDF (327KB)(1083)
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