2010 Vol. 28, No. 5
Display Method:
2010, 28(5): 331-333.
Abstract:
Objective To study the pharmacokinetics of compound Danshen dropping pills of new matrix. Methods HPLC was used as a detection method.New Zealand rabbits were taken as experimental animals.The compound Danshen dropping pills sold in market were tak...
Objective To study the pharmacokinetics of compound Danshen dropping pills of new matrix. Methods HPLC was used as a detection method.New Zealand rabbits were taken as experimental animals.The compound Danshen dropping pills sold in market were tak...
2010, 28(5): 334-338.
Abstract:
Objective To establish a method of HPLC for the simultaneous quantification of three sesquiterpene lactones in Inula racemosa. Methods Agilent Zorbax XDB-C18 column(250 mm×4.6 mm,5 μm) was uesed with a mobile phase consists of 55% acetonitrile and ...
Objective To establish a method of HPLC for the simultaneous quantification of three sesquiterpene lactones in Inula racemosa. Methods Agilent Zorbax XDB-C18 column(250 mm×4.6 mm,5 μm) was uesed with a mobile phase consists of 55% acetonitrile and ...
2010, 28(5): 339-341,344.
Abstract:
Objective To prepare Nimodipine solid dispersion and increase its dissolution rate.Methonds Using polyvinylpyrrolidone(PVP) as a carrier,nimodipine solid dispersion was prepared by spray-drying method.differential scanning calorimetry and X-Ray powd...
Objective To prepare Nimodipine solid dispersion and increase its dissolution rate.Methonds Using polyvinylpyrrolidone(PVP) as a carrier,nimodipine solid dispersion was prepared by spray-drying method.differential scanning calorimetry and X-Ray powd...
2010, 28(5): 342-344.
Abstract:
Objective To determine Pb,Cd,Hg,As,U,Th,Tl in nine clinical commonly used Chinese traditional medicine treating diabetes mellitus,which provide reference data for modern medication.Methonds The samples were treated by microwave digestion,and determi...
Objective To determine Pb,Cd,Hg,As,U,Th,Tl in nine clinical commonly used Chinese traditional medicine treating diabetes mellitus,which provide reference data for modern medication.Methonds The samples were treated by microwave digestion,and determi...
2010, 28(5): 345-347,384.
Abstract:
Objective To prepare N-tert-butoxycarbonyl-DL-(±)-homo-tyrosine(1),a key unusual amino acid and pharmaceutical intermediate for the total synthesis of novel peptides drug including cyclic or straight chain peptide. Methods Starting from L-aspartic ...
Objective To prepare N-tert-butoxycarbonyl-DL-(±)-homo-tyrosine(1),a key unusual amino acid and pharmaceutical intermediate for the total synthesis of novel peptides drug including cyclic or straight chain peptide. Methods Starting from L-aspartic ...
2010, 28(5): 348-351.
Abstract:
Objective To observe the effects of Protoveratrine A(PA) on cardiovascular and respiratory system in rats. Methods The experimental rats(n=40,mf=1:1) were equally randomized into 4 groups: blank control group and groups of low dose(ig,0.25 mg/kg,s...
Objective To observe the effects of Protoveratrine A(PA) on cardiovascular and respiratory system in rats. Methods The experimental rats(n=40,mf=1:1) were equally randomized into 4 groups: blank control group and groups of low dose(ig,0.25 mg/kg,s...
2010, 28(5): 352-353,380.
Abstract:
Objective To study the hepatoprotective effect of shugananlening extract against mice liver damage which induced by carbon tetrachloride(CCl4). Methods Acute chemical liver jnjury model was induced by CCl4 in mice.The activities of ALT,AST in serum...
Objective To study the hepatoprotective effect of shugananlening extract against mice liver damage which induced by carbon tetrachloride(CCl4). Methods Acute chemical liver jnjury model was induced by CCl4 in mice.The activities of ALT,AST in serum...
2010, 28(5): 354-355,358.
Abstract:
Objective To select four processed rhubarb products(i.e.,crude rhubarb,prepared rhubarb,rhubarb charcoal and rhubard stir-fried with wine) and to compare their function on promoting blood circulation to remove blood stasis. Methods The different fu...
Objective To select four processed rhubarb products(i.e.,crude rhubarb,prepared rhubarb,rhubarb charcoal and rhubard stir-fried with wine) and to compare their function on promoting blood circulation to remove blood stasis. Methods The different fu...
2010, 28(5): 356-358.
Abstract:
Objective To observe the analgesia effect and safety of Fentanyl Transdermal System and tramadol for day surgery patients with anus surgeries. Methods 120 cases of anus surgeries undergo spinal anesthesia were randomly divided into three groups.Pat...
Objective To observe the analgesia effect and safety of Fentanyl Transdermal System and tramadol for day surgery patients with anus surgeries. Methods 120 cases of anus surgeries undergo spinal anesthesia were randomly divided into three groups.Pat...
2010, 28(5): 361-362.
Abstract:
Objective To investigate chemical stability of cyclophosphamid in glass bottles and PVC infusion bags. Methods Cyclophosphamide was dissolved with 0.9% sodium chloride respectively in glass bottles and PVC bags.The storage condition for the solutio...
Objective To investigate chemical stability of cyclophosphamid in glass bottles and PVC infusion bags. Methods Cyclophosphamide was dissolved with 0.9% sodium chloride respectively in glass bottles and PVC bags.The storage condition for the solutio...
2010, 28(5): 363-365,368.
Abstract:
Objective To develop a method to study the pharmacokinetics of tinidazole pectin matrics colon-specific sustained-release tablets in dogs. Methods The plasma concentrations were determined by HPLC.Two-period cross over self-control trail was conduc...
Objective To develop a method to study the pharmacokinetics of tinidazole pectin matrics colon-specific sustained-release tablets in dogs. Methods The plasma concentrations were determined by HPLC.Two-period cross over self-control trail was conduc...
2010, 28(5): 366-368.
Abstract:
Objective To improve the preparation method for furacillin solution and observe the stability of the solution. Methods The original preparation technics was modified.The furacillin solution was qualitatively analyzed by observation and quantitative...
Objective To improve the preparation method for furacillin solution and observe the stability of the solution. Methods The original preparation technics was modified.The furacillin solution was qualitatively analyzed by observation and quantitative...
2010, 28(5): 369-371,382.
Abstract:
Objective To establish a method for the determination of in vitro release of thienorphine hydrochloride micro-spheres with a good correlation between in vivo and in vitro. Methods Immediate release and dialysis release Methods were used to determin...
Objective To establish a method for the determination of in vitro release of thienorphine hydrochloride micro-spheres with a good correlation between in vivo and in vitro. Methods Immediate release and dialysis release Methods were used to determin...
2010, 28(5): 372-373,395.
Abstract:
Objective To develop liquid chromatography with tandem mass spectrometry(LC-MS/MS) detection for the content determination of carbamazepine tablet. Methods The method was used.The sample was analyzed on Zorbax Extend-C18(150 mm×4.6 mm,5 μm),with mo...
Objective To develop liquid chromatography with tandem mass spectrometry(LC-MS/MS) detection for the content determination of carbamazepine tablet. Methods The method was used.The sample was analyzed on Zorbax Extend-C18(150 mm×4.6 mm,5 μm),with mo...
2010, 28(5): 374-377.
Abstract:
Objective To provide evidences for clinical rational use and scientific management of the anti-infection drugs through investigating the application status of the anti-infection drugs in our hospital. Methods Utilization of anti-infection drugs was...
Objective To provide evidences for clinical rational use and scientific management of the anti-infection drugs through investigating the application status of the anti-infection drugs in our hospital. Methods Utilization of anti-infection drugs was...