不同产地楮实子提取物体外抗氧化作用及其质量比较
Antioxidation effect in vitro and quality comparison of Broussonetia paperifera fruits from different habitats
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摘要: 目的 :对10个不同产地楮实子的乙醇、水提物进行体外抗氧化作用研究,并按中国药典部分质量标准对不同产地的楮实子进行质量比较。 方法 :采用不同产地的楮实子醇、水提取物对大鼠肝组织匀浆脂质过氧化作用的抑制,评价其体外抗氧化作用,并对不同产地的楮实子的灰分及提取物含量进行比较。 结果 :不同产地楮实子的抗氧化能力差别较大,其中安徽、山西和广西产的楮实子抗氧化能力最强,灰分含量以山东、浙江和广东三产地的较好。 结论 :不同产地楮实子的质量有很大差异,其提取物有较明显的体外抗氧化活性, 并建议中国药典再版时收载楮实子提取物含量标准。Abstract: Objective : To study antioxidalion effect of ethanol and aqueous extracts of Broussonetia paperifera fruits from 10 different habitats and assess their qualities by standards of China Pharmacopeia. Methods : MDA production in rats liver homogenate induced by auto-oxidation was measured by MDA kits method and the contents of ashes, elhanol and aqueous extracts were detected. Results : Antioxidation potential of Broussonetia paperifera fruits from Anhui, Shanxi and Cuangxi were significant and contents of ashes were lower from Shandong, Zhejiang and Guangdong than other places. Conclusion : Extracts of Broussonetia paperifera fruits have an-tioxidation effect in vitro, and we suggest that contents of extracts of Broussonetia paperifera fruits be included in next CHP.
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