成年女性不同年龄组的肝代谢功能研究
Study on liver metabolism function in adult female at different ages
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摘要: 目的 探讨健康成年女性不同年龄组肝代谢功能的差别.方法 用RP-HPLC检测49例18～34岁.46例35～50岁,18例51～60岁成年女性健康受试者的唾液咖啡因清除率(SCL).结果 18～34岁年龄组的SCL在正常值范围,18～34岁年龄组、35～50岁年龄组和51～60岁年龄组各组间比较,差别显著(P<0.001).结论 女性随着年龄的增长,SCL下降,肝代谢功能减低.Abstract: Objective To investigate the difference of liver metabolism function in healthy adult female at different ages. Methods The saliva caffeine clearance(SCL) was determined by RP-HPLC method in 49 healthy adult females aged 18～34 years, 46 aged 35～50 and 18 aged 51～60 years. Results The SCL of 18～34 year group was normal. There was significant difference between 18～34 year group and others(P<0.001), significant difference was also found between 35～50 year group and 51～60 year group(P<0.001). Conclusion The SCL in female decreased with age and the liver metabolism function become lower.
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Key words:
- adult female /
- caffeine clearance /
- liver metabolism function
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