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2021 Vol. 39, No. 3

Cover Catalogue
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Mechanism of Qingkailing on influenza based on network pharmacology and molecular docking
CAI Mengcheng, LIU Yiqun, YU Chaoqin, JIN Yongsheng
2021, 39(3): 193-202. doi: 10.12206/j.issn.1006-0111.202005077
Abstract(9207) HTML (3593) PDF (9657KB)(121) Cited By (3)
Abstract:
Objective  To explore the potential mechanism of Qingkailing (QKL) on influenza, and to provide a theoretical basis for the clinical application of QKL.  Methods  TCMSP, TCMID, and PubChem databases were used to search for the active ingredients a...
Application of edible Chinese medicine in epidemic prevention
XU Shengyan, XIA Tianshuang, XU Wumu, HAN Ting, YUE Xiaoqiang, XIN Hailiang
2021, 39(3): 203-205, 220. doi: 10.12206/j.issn.1006-0111.202009026
Abstract(7385) HTML (2539) PDF (836KB)(48) Cited By (6)
Abstract:
Edible Chinese medicine is a significant part of traditional Chinese medicine. With the concept of "disease prevention", it can be used in all stages of epidemic prevention and control. This paper introduced the current status of anti-epidemic applic...
Quality evaluation of clinical trial literatures on the COVID-19 treatment with traditional Chinese medicine (TCM)
JIN Jiangwei, SHI Jianrong, CAI Jian, LI Guihua, LU Saihua, XU Feng
2021, 39(3): 206-210. doi: 10.12206/j.issn.1006-0111.202012012
Abstract(7104) HTML (2983) PDF (884KB)(48) Cited By (4)
Abstract:
Objective  To evaluate the quality of the clinical trial literatures published on the treatment of COVID-19 with TCM, find out the shortcomings and put forward corresponding suggestions, in order to promote TCM against COVID-19.  Methods  "COVID-1...
Research progress in nanomaterials in hemostasis
WANG Jirong, GONG Hai, LU Guangzhao, DENG Li
2021, 39(3): 211-214. doi: 10.12206/j.issn.1006-0111.202012015
Abstract(5485) HTML (3563) PDF (827KB)(48) Cited By (3)
Abstract:
Nanomaterials, with the advantages of unique microstructure, have been widely used in the fields of material manufacturing, microelectronics and computer technology, medicine and health, environment and energy. Compared with traditional hemostatic ma...
Effects of MCCC2 knockdown on proliferation, migration and apoptosis of DU145 prostate cancer cells
CHEN Xue, HUANG Zehao, ZHENG Chengjian
2021, 39(3): 215-220. doi: 10.12206/j.issn.1006-0111.202104020
Abstract(5045) HTML (1645) PDF (1896KB)(21)
Abstract:
Objective  To investigate the change of biological characteristics after stable knockdown of the coding gene of 3-methylcrotonyl-coenzyme A carboxylase β subunit (MCCC2) expression in DU145 by lentivirus shRNA.  Methods  Three groups were included...
Effects of Humulus lupulus L. and its active ingredient xanthohumol on preventing glucocorticoid-induced osteoporosis
XIA Tianshuang, DING Luying, ZHANG Jiabao, LI Xiaojin, WANG Guoping, XIN Hailiang
2021, 39(3): 221-225. doi: 10.12206/j.issn.1006-0111.202102002
Abstract(4341) HTML (1708) PDF (1287KB)(14) Cited By (4)
Abstract:
Objective  To explore the effects of Humulus lupulus L. extract (HLE) and xanthohumol (XN) on preventing glucocorticoid-induced osteoporosis (GIOP).  Methods  The GIOP model was established by intraperitoneal injection of dexamethasone (DEX). Bone...
Anti-inflammatory and analgesic activity analysis of Yinlian Tongfeng granules based on network Pharmacology
XU Yi, LIU Jing, HUANG Jin, CUI Jingang
2021, 39(3): 226-231, 254. doi: 10.12206/j.issn.1006-0111.202007014
Abstract(7098) HTML (2615) PDF (9602KB)(48)
Abstract:
Objective  To explore the anti-inflammatory and analgesic mechanism of Yinlian Tongfeng granules by network pharmacology.  Methods  Three main active components of Yinlian Tongfeng granules were collected from TCMSP database to predict its effecti...
Mechanism of Jiangzhihugan capsule in treatment of fatty liver based on network pharmacology
CAI Mengcheng, JIN Yongsheng, ZHENG Wei, YUAN Zike, GUO Liangjun
2021, 39(3): 232-239, 248. doi: 10.12206/j.issn.1006-0111.202006054
Abstract(8411) HTML (2155) PDF (9450KB)(32) Cited By (2)
Abstract:
Objective  To explore the potential mechanism of Jiangzhihugan capsule (JZHG) for fatty liver (FL), and to provide a theoretical guideline for the clinical application of JZHG.  Methods  TCMSP and TCMID databases were used to search for the active...
Protective effect of Shengxian decoction and the decoction of single herb component against myocardial injury induced by hypoxia/reoxygenation
JIN Xiaoling, CHEN Lan, ZHANG Feng, HUANG Doudou, LIAO Lina, CHEN Wansheng
2021, 39(3): 240-244. doi: 10.12206/j.issn.1006-0111.202006080
Abstract(4075) HTML (2019) PDF (1299KB)(16) Cited By (6)
Abstract:
Objective  To study the protective effect of Shengxian decoction and the single herb decoction against myocardial injury induced by hypoxia/reoxygenation.  Methods  The H9c2 cells were cultured to establish hypoxia/reoxygenation model. Rats were d...
Effects of SLCO1B1 521 T>C and APOE gene polymorphisms on lipid-lowering efficacy and adverse reactions of atorvastatin
LIU Yanhui, DONG Jing, LU Yan, LU Man, DING Yunhe, LI Wenyan
2021, 39(3): 245-248. doi: 10.12206/j.issn.1006-0111.202012013
Abstract(5173) HTML (1654) PDF (940KB)(32)
Abstract:
Objective  To study the effect of SLCO1B1 521 T>C and APOE gene polymorphisms on the clinical efficacy and safety of atorvastatin in ischemic stroke patients with dyslipidemia.  Methods  210 cases of ischemic stroke with dyslipidemia were enrolled...
Study on the antifungal activity of phenazine derivatives
QIU Lijuan, CHAO Wen, SHI Anjie, YAN Lan, LÜ Quanzhen, JIANG Yuanying
2021, 39(3): 249-254. doi: 10.12206/j.issn.1006-0111.202103083
Abstract(4459) HTML (1629) PDF (1102KB)(32)
Abstract:
Objective  To study the antifungal activity of phenazines derivatives.  Methods  The anti-fungal activity of phenazine compounds was evaluated initially with micro-liquid dilution. No significant antifungal activity against Candida albicans was fo...
Therapeutic effects study on the contents of dihydromyricetin in ampelopsis grossedentata from different places and their compatibility with fructus arctiine
SUN Rui, FU Li, LEI Yu
2021, 39(3): 255-258, 266. doi: 10.12206/j.issn.1006-0111.202103084
Abstract(4280) HTML (1386) PDF (958KB)(24) Cited By (3)
Abstract:
Objective  To study the content differences of Dihydromyricetin in Ampelopsis grossedentata from different origins, parts and processing techniques, and improve the therapeutic effects by optimizing the compatibility of Ampelopsis grossedentata with...
Network Meta-analysis on efficacy and safety of non-steroidal anti-inflammatory drugs for osteoarthritis in middle aged and old people
SUN Bin, WANG Zijing, CAO Yang, MENG Rui, YANG Lan, ZHU Jinbao
2021, 39(3): 259-266. doi: 10.12206/j.issn.1006-0111.202101022
Abstract(6392) HTML (4724) PDF (1987KB)(61) Cited By (31)
Abstract:
Objective  To systematically evaluate the efficacy and safety of different non-steroidal anti-inflammatory drugs (NSAIDs) in middle-aged and old Chinese patients with osteoarthritis(OA).  Methods  A systematic literature search was conducted throu...
Simultaneous determination of three components in pharmacy compounded terbinafine ointment by HPLC method
YAN Jia, SONG Hongtao, ZHOU Xin
2021, 39(3): 267-269, 279. doi: 10.12206/j.issn.1006-0111.202007109
Abstract(5087) HTML (1528) PDF (898KB)(40)
Abstract:
Objective  To establish a method to assay 3 active components in pharmacy compounded terbinafine ointment simultaneously.  Methods  High performance liquid chromatography (HPLC) equipped with the ZORBAX SB-C8 (4.6 mm×250 mm, 5 μm) was used for the...
One step assay of the four plant ingredients in Yangxue Anshen syrup by HPLC method
LU Ping, NI Dongjie, ZHENG Wei, GUO Liangjun, WANG Xiang
2021, 39(3): 270-273. doi: 10.12206/j.issn.1006-0111.202006072
Abstract(4803) HTML (1365) PDF (915KB)(31) Cited By (1)
Abstract:
Objective  To establish a HPLC method for simultaneous determination of quercitrin, luteoloside, rutin and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in Yangxue Anshen syrup.  Methods  Waters symmetry C18 column (250 mm×4.6 mm, 5 μm) was used...
Meta-analysis on the efficacy and safety of β- lactams combined with macrolides in the treatment of community-acquired pneumonia in children
GE Jiajia, ZHANG Yingying
2021, 39(3): 274-279. doi: 10.12206/j.issn.1006-0111.202007077
Abstract(4572) HTML (1197) PDF (1098KB)(19) Cited By (2)
Abstract:
Objective  To compare the efficacy and safety of β - lactams alone and the combination of β - lactams with macrolides in the treatment of community-acquired pneumonia(CAP) in children.  Methods  PubMed, CNKI and VIP databases were searched by comp...
Overseas warehouses for prepositioning medicine materials
CHEN Jing, CUI Lijun, LI Ruimin, ZHANG Yiqian, LUAN Zhipeng, SHU Lixin
2021, 39(3): 280-282, 286. doi: 10.12206/j.issn.1006-0111.202101005
Abstract(3863) HTML (1130) PDF (851KB)(18)
Abstract:
In order to meet our country strategic needs of “The Belt and Road”, it was proposed to use the existing overseas warehouses from domestic companies as prepositioning locations. The situation and functionality were clarified. A comprehensive evaluati...
Survey and intervention countermeasures on occupational stress of young hospital pharmacists
WU Jiahao, GU Lin, LI Guihua, FANG Ming, WANG Yan, LU Saihua, XU Feng
2021, 39(3): 283-286. doi: 10.12206/j.issn.1006-0111.202012007
Abstract(3991) HTML (1244) PDF (974KB)(20) Cited By (1)
Abstract:
Objective  To investigate the occupational life status and occupational related stress factors of young hospital pharmacists, and to promote the healthy development of young pharmacists.  Methods  Questionnaire was designed and released on-line th...
GMP Defects in the field inspection for processed Chinese herbal medicine manufacturers in Anhui Province during 2014 to 2018
YIN Pengjun, HU Shigao
2021, 39(3): 287-290. doi: 10.12206/j.issn.1006-0111.202101010
Abstract(3551) HTML (1039) PDF (849KB)(18) Cited By (27)
Abstract:
Objective  To propose the improvement measures and suggestions for the better quality management of processed Chinese herbal medicine production and provide insights and solutions for the quality control of processed Chinese herbal medicine producti...