2021 Vol. 39, No. 4
Display Method:
2021, 39(4): 291-294, 361.
doi: 10.12206/j.issn.1006-0111.202011002
Abstract:
The outbreak of COVID-19 posed a huge threat to human health and social stability. With the rapid spread of the virus around the world, the drug development and related research of novel coronavirus (SARS-CoV-2) have become an urgent issue in the med...
The outbreak of COVID-19 posed a huge threat to human health and social stability. With the rapid spread of the virus around the world, the drug development and related research of novel coronavirus (SARS-CoV-2) have become an urgent issue in the med...
2021, 39(4): 295-298, 304.
doi: 10.12206/j.issn.1006-0111.202103001
Abstract:
The global morbidity and mortality of cardiovascular diseases remain high. Atherosclerosis is an important pathological basis of cardiovascular diseases, and its pathogenic mechanism has not been fully clarified. It was reported that pathogenic mecha...
The global morbidity and mortality of cardiovascular diseases remain high. Atherosclerosis is an important pathological basis of cardiovascular diseases, and its pathogenic mechanism has not been fully clarified. It was reported that pathogenic mecha...
2021, 39(4): 299-304.
doi: 10.12206/j.issn.1006-0111.202008046
Abstract:
Liquid band-aid is a new type of wound dressing that has emerged in recent years. Compared with traditional band-aid, it has the advantages of convenient use, natural shedding, good waterproof and breathable effect, and easy fitting for irregular wou...
Liquid band-aid is a new type of wound dressing that has emerged in recent years. Compared with traditional band-aid, it has the advantages of convenient use, natural shedding, good waterproof and breathable effect, and easy fitting for irregular wou...
2021, 39(4): 305-308.
doi: 10.12206/j.issn.1006-0111.202012008
Abstract:
Objective To synthesize and investigate cytotoxicity of an indole-chalcone derivative FC58. Methods The target compound was synthesized through the Aldol condensation with 1-(3,4,5-trimethoxyphenyl)ethan-1-one and 1H-indole-3-carbaldehyde. The ...
2021, 39(4): 309-312, 378.
doi: 10.12206/j.issn.1006-0111.202009048
Abstract:
Objective To establish an HPLC method for simultaneous assay of macrocyclic polyphenols from Penthorum chinense Pursh, pinocembrin-7-O-[4'', 6''-(S)-hexahydroxydiphenoyl]-β-D-glucose (PHG), pinocembrin-7-O-[3''-O-galloyl-4'', 6''-(S)-hexahydroxydip...
2021, 39(4): 313-316, 330.
doi: 10.12206/j.issn.1006-0111.202008102
Abstract:
Objective To establish an HPLC method for the simultaneous determination of harpagide and harpagoside content in Scrophularia ningpoensis (SN). Methods An Eclipse C18 column was used for determination of methanol extract of S. ningpoensis with ...
2021, 39(4): 317-321, 330.
doi: 10.12206/j.issn.1006-0111.202007053
Abstract:
Objective To study the protective effect of active peptide GRGDS on rat nerve cells (PC12 cells) in oxygen glucose deprivation (OGD) injury model and explore its mechanism of action. Methods PC12 cells were divided into control group, ODG group...
2021, 39(4): 322-330.
doi: 10.12206/j.issn.1006-0111.202101036
Abstract:
Objective To analyze the chemical components in the ethanol extract of Sanse tablets with anti-complement activity, and to provide scientific basis for its therapeutic effects. Methods The classical anti-complement pathway was used to compar...
2021, 39(4): 331-335.
doi: 10.12206/j.issn.1006-0111.202106136
Abstract:
Objective To understand the development status in the subject of pharmacy and provide recommendations for the construction of universities and the development of pharmacy by the bibliometric analysis of pharmaceutical papers from Double First-rate ...
2021, 39(4): 336-339.
doi: 10.12206/j.issn.1006-0111.202012005
Abstract:
Objective Asiatic acid is the main medicinal component of aursane pentacyclic triterpene and possessed various biological activities. In order to obtain better active Asiatic acid analogues, microbial transformation was used for structural modifica...
2021, 39(4): 340-344, 358.
doi: 10.12206/j.issn.1006-0111.202103028
Abstract:
Objective To investigate the anti-inflammatory role of α7 nicotinic acetylcholine receptor (α7nAChR) under inflammatory stress and its mechanisms. Methods PNU282987 was used for the activation of α7nAChR and LPS was administrated as inflammator...
2021, 39(4): 345-347, 368.
doi: 10.12206/j.issn.1006-0111.202012011
Abstract:
Objective To optimize the method of assay for silver sulfadiazine, and to investigate its stability in high temperature, humidity and salt environment. Methods Agilent ZORBAX SB-C18 column was used in HPLC for the determination of silver sulfad...
2021, 39(4): 348-351, 365.
doi: 10.12206/j.issn.1006-0111.202102011
Abstract:
Objective To establish an UHPLC-MS/MS method for the determination of uracil (U) and dihydrouracil (UH2) in human plasma. Methods A positive ion detection mode was adopted on the Agilent 6460A mass spectrometer. Chlorouracil was used as the int...
2021, 39(4): 352-358.
doi: 10.12206/j.issn.1006-0111.202007101
Abstract:
Objective To evaluate the pharmacokinetics of the new mesalazine enteric-coated sustained-release granules in SD rats and their distribution in the gastrointestinal tract, and to understand the preclinical pharmacokinetics and gastrointestinal dist...
2021, 39(4): 359-361.
doi: 10.12206/j.issn.1006-0111.202101028
Abstract:
Objective By participating in the process of drug treatment and pharmaceutical monitoring for a patient with cancer pain, clinical pharmacists participated in formulating drug treatment plans and proposed rational medication recommendations. At the...
2021, 39(4): 362-365.
doi: 10.12206/j.issn.1006-0111.202102020
Abstract:
Objective To evaluate the application value of tranexamic acid in total knee arthroplasty. Methods 120 elderly patients with knee osteoarthritis admitted to Department of Joint Surgery in our hospital from December 2018 to March 2020 were selec...
2021, 39(4): 366-368.
doi: 10.12206/j.issn.1006-0111.202006099
Abstract:
Objective To explore the clinical efficacy of acupuncture combined with SSRIs in the treatment of patients with depression. Methods A total of 83 patients with depression admitted to our hospital between January 2019 and January 2020 were sele...
2021, 39(4): 369-372.
doi: 10.12206/j.issn.1006-0111.202105125
Abstract:
Objective to analyze the differences and changes before and after the introduction of supply processing distribution (SPD) supply chain management mode in a public hospital, analyze the typical problems existing in the clinical practice and develop...
2021, 39(4): 373-378.
doi: 10.12206/j.issn.1006-0111.202007011
Abstract:
Objective To systematically evaluate the efficacy and safety of ceftazidime/avibactam(CAZ/AVI) in the treatment of carbapenem-resistant Enterobacteriaceae(CRE) or carbapenem-resistance Klebsiella pneumonia (CRKP), and to provide evidence-cased refe...
2021, 39(4): 379-383.
doi: 10.12206/j.issn.1006-0111.202103025
Abstract:
Objective To analyze the drug consumption of the joint logistics support force during field training in Yunnan, summarize the drug use characteristics of medical staff, and analyze the drug use rules, so as to provide the basis for modular drug sup...
Contribution System
Author Login
Review Login
Editor Login
Reader Login
News