2021 Vol. 39, No. 5
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2021, 39(5): 387-390, 436.
doi: 10.12206/j.issn.1006-0111.202101012
Abstract:
Herba Monochasmae savatii, whole plant of the Monochasma savatier Franch. or Monochasma sheareri Franch. ex Maxim., scrophulariaceae, was first found in "Zhiwu Mingshi Tukao". It has the effects of clearing heat and detoxicating, dispelling wind and...
Herba Monochasmae savatii, whole plant of the Monochasma savatier Franch. or Monochasma sheareri Franch. ex Maxim., scrophulariaceae, was first found in "Zhiwu Mingshi Tukao". It has the effects of clearing heat and detoxicating, dispelling wind and...
2021, 39(5): 391-394, 430.
doi: 10.12206/j.issn.1006-0111.202101027
Abstract:
Due to the limited self-repair ability of neurons after injury, there has been a lack of effective treatments for nerve injury in clinical practice. So, to find drugs that promote the repair after nerve injury has become a research hotspot. Schwann c...
Due to the limited self-repair ability of neurons after injury, there has been a lack of effective treatments for nerve injury in clinical practice. So, to find drugs that promote the repair after nerve injury has become a research hotspot. Schwann c...
2021, 39(5): 395-398.
doi: 10.12206/j.issn.1006-0111.202103006
Abstract:
Prokineticin 2 (PK2) is a newly discovered chemokine, which participates in various physiological functions of the body by binding to receptors PKR1 and PKR2. PK signaling pathway is a newly discovered important regulatory pathway for the occurrence ...
Prokineticin 2 (PK2) is a newly discovered chemokine, which participates in various physiological functions of the body by binding to receptors PKR1 and PKR2. PK signaling pathway is a newly discovered important regulatory pathway for the occurrence ...
2021, 39(5): 399-402, 441.
doi: 10.12206/j.issn.1006-0111.202101011
Abstract:
Objective To investigate the main chemical constituents of the low polarity extracts from pinusmassoniana Lamb. leaves and their synergetic activity with fluconazole against fluconazole-resistant Candida albicans. Methods The pinusmassoniana le...
2021, 39(5): 403-408, 471.
doi: 10.12206/j.issn.1006-0111.202101035
Abstract:
Objective To evaluate therapeutic effects of dihydrotanshinone Ⅰ on hepatic fibrosis based on liver metabolomics method. Methods 28 rats were randomly divided into four groups including control group, hepatic fibrosis model group and dihydrotan...
2021, 39(5): 409-414, 464.
doi: 10.12206/j.issn.1006-0111.202104119
Abstract:
Objective To study the effect of optimized atropine administration regimen on myopia in guinea pigs. Methods Forty six 21-day old guinea pigs were used for this study. Six were randomly selected as blank control, and the remaining 40 were rand...
2021, 39(5): 415-421.
doi: 10.12206/j.issn.1006-0111.202106091
Abstract:
Objective To establish an assay method for diphenhydramine hydrochloride and caffeine in rat plasma by UPLC-MS/MS for pharmacokinetic study. Methods The chromatographic separation was performed on an ACE 3 C18-PFP (3.0 mm×150 mm, 3 μm) by isoc...
2021, 39(5): 422-425, 459.
doi: 10.12206/j.issn.1006-0111.202012018
Abstract:
Objective To establish an UV spectrophotometry method for the determination of total flavonoids in Oxytropis falcata Bunge. Methods Using rutin as comparison, three coloration methods were used to find the optimal assay method, optimize the col...
2021, 39(5): 426-430.
doi: 10.12206/j.issn.1006-0111.202101025
Abstract:
Objective To investigate the stability of 8 commonly used reference solutions and determine the validity period of internal control. Methods The storage solutions of reference substances were prepared and stored in the refrigerator at 2 to 10 ℃...
2021, 39(5): 431-436.
doi: 10.12206/j.issn.1006-0111.202101021
Abstract:
Objective To establish a HPLC fingerprints of Biyuanjing capsules. Methods The column was Agilent SB-C18(4.6mm×250 mm, 5 µm). The mobile phase was acetonitrile-water with gradient elution at a flow rate of 1.0 ml/min. The detection wavelength w...
2021, 39(5): 437-441.
doi: 10.12206/j.issn.1006-0111.202102010
Abstract:
Objective To develop an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to simultaneously detect the contents of gallic acid, syringin, phellodendrine, aesculin and rhein in the gallnut lotion. Me...
2021, 39(5): 442-446.
doi: 10.12206/j.issn.1006-0111.202104134
Abstract:
Objective To understand the current situation of pharmaceutical research development in China and provide a constructive thinking for universities to serve the national innovation strategy through the statistical analysis of pharmaceutical papers a...
2021, 39(5): 447-448, 453.
doi: 10.12206/j.issn.1006-0111.202103041
Abstract:
Objective To establish quantitative methods to assay quercetin in Honghuixiang injection by HPLC. Methods Dikma C18 column(250 mm×4.6 mm, 5 μm) was used for the assay with acetonitrile −0.1% phosphoric acid (25∶75) as the mobile phase. Flow rat...
2021, 39(5): 449-453.
doi: 10.12206/j.issn.1006-0111.202102005
Abstract:
Objective To study the immunomodulatory effect of polysaccharides (CRPS25-Ⅱ) derived from Chroogomphus rutilus on mouse mononuclear macrophages, RAW264.7 cells. Methods RAW264.7 cells were resuspended and cultured, cell suspension was prepared...
2021, 39(5): 454-459.
doi: 10.12206/j.issn.1006-0111.202012021
Abstract:
Objective To evaluate the efficacy and safety of Llianhua Qingwen capsule versus oseltamivir in the treatment of influenza. Methods Data from PubMed, Cochrane Library, Embase, VIP, CNKI and CBM, RCTs about Lianhua Qingwen capsule or Lianhua Qin...
2021, 39(5): 460-464.
doi: 10.12206/j.issn.1006-0111.202101037
Abstract:
Objective To provide reference for clinical pharmacists to participate in rational drug use through case study. Methods Clinical pharmacists participated in the optimization of treatment plan and performed pharmaceutical care for the patients a...
2021, 39(5): 465-467, 475.
doi: 10.12206/j.issn.1006-0111.202103002
Abstract:
Objective To observe the effect of tiopronin combined with glutathione on the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), glutamyltransferase (GGT),blood fat and laminin (LN) in patients with non-alcoholic fatty live...
2021, 39(5): 468-471.
doi: 10.12206/j.issn.1006-0111.202103009
Abstract:
Objective Through clinical pharmacists participating in the treatment of hip prosthesis infection, to explore the factors of Salmonella infection and skin itching, and to increase the importance of Salmonella infection and the pharmaceutical monito...
2021, 39(5): 472-475.
doi: 10.12206/j.issn.1006-0111.202008029
Abstract:
Objective To explore the effect of CYP2C19 gene polymorphism on clopidogrel plasma concentration, rate of platelet inhibition and safety. Methods We screen the patients who took clopidogrel after PCI in our hospital, according to the inclusion ...
2021, 39(5): 476-478.
doi: 10.12206/j.issn.1006-0111.202102018
Abstract:
Objective To analyze the clinical efficacy of Fuming tablets and lecithin-complexed iodine tablets in the treatment of vitreous opacities. Methods 80 patients with vitreous opacities admitted to the department of ophthalmology in the central re...
2021, 39(5): 479-482.
doi: 10.12206/j.issn.1006-0111.202101013
Abstract:
Objective To explore the effect of budesonide suspension for inhalation in the treatment of childhood asthma and its influence on growth and development in 1-2 years. Methods The 68 children with asthma admitted to our hospital from October 201...
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