2021 Vol. 39, No. 6
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2021, 39(6): 483-486.
doi: 10.12206/j.issn.1006-0111.202103038
Abstract:
Objective To discuss the system and classification of military pharmacy disciplines. Methods Based on the analysis and induction of the military pharmacy subject positioning, classification status, classification ideas and classification metho...
2021, 39(6): 487-490, 498.
doi: 10.12206/j.issn.1006-0111.202008026
Abstract:
Innate immunity is the host's first line defense against pathogens invading to the body. Detection of abnormal nucleic acids in the cytoplasm showed that some conserved pathogen associated molecular patterns (PAMPS) triggered type I interferon (IFN) ...
Innate immunity is the host's first line defense against pathogens invading to the body. Detection of abnormal nucleic acids in the cytoplasm showed that some conserved pathogen associated molecular patterns (PAMPS) triggered type I interferon (IFN) ...
2021, 39(6): 491-498.
doi: 10.12206/j.issn.1006-0111.202105040
Abstract:
Sepsis can cause life-threatening organ dysfunction and is one of the leading causes of death in critically ill patients. Early diagnosis and correct treatment of sepsis are the key to reducing the fatality, however, there is no golden standard for d...
Sepsis can cause life-threatening organ dysfunction and is one of the leading causes of death in critically ill patients. Early diagnosis and correct treatment of sepsis are the key to reducing the fatality, however, there is no golden standard for d...
2021, 39(6): 499-503, 533.
doi: 10.12206/j.issn.1006-0111.202106123
Abstract:
Objective To study the effects of schisandrin B (Sch B) on the apoptosis of human breast cancer MDA-MB-231 cells and its mechanism. Methods Cell counting reagent (CCK-8) was used to detect the effect of Sch B on the survival rate of MDA-MB-231...
2021, 39(6): 504-508.
doi: 10.12206/j.issn.1006-0111.202101001
Abstract:
Objective To investigate the protective effect of the ethanol extract of Portulaca oleracea L. on acute liver injury induced by carbon tetrachloride in mice, and to analyze its effective components. Methods 8 0% ethanol purslane extract was centri...
2021, 39(6): 509-514.
doi: 10.12206/j.issn.1006-0111.202103018
Abstract:
Objective To explore the effects of Humulus lupulus L. extract (HLE) and its mechanism on improving bone formation of Aβ-injured osteoblasts. Methods Osteoblasts isolated from 24 h-old Wistar rats were injured by Aβ1-42 oligomer and intervened...
2021, 39(6): 515-519, 537.
doi: 10.12206/j.issn.1006-0111.202105137
Abstract:
Objective To find small molecules binding specifically to signal transducer and activator of transcription3 (STAT3) based on surface plasmon resonance (SPR) technology and confirm their inhibitory activities to STAT3. Methods The biomolecular ...
2021, 39(6): 520-524, 556.
doi: 10.12206/j.issn.1006-0111.202108094
Abstract:
Objective To compare the differences in the anti-tumor growth effects of organisms with different injections of CT26 tumor cell RNA loaded into nanoliposomes. Methods The extracted tumor RNA was loaded into nanoliposomes to prepare tumor RNA n...
2021, 39(6): 525-528.
doi: 10.12206/j.issn.1006-0111.202009023
Abstract:
Objective To optimize the synthesis method of 18F-T807 and study preliminary biodistribution. Methods 18F-T807 was synthesized using an optimized method in TRACERlab FXFN synthesizer with a t-BOC（t-Butyloxy carbonyl）-protected 18F-T807 precurs...
2021, 39(6): 529-533.
doi: 10.12206/j.issn.1006-0111.202104014
Abstract:
Objective To investigate the effects of ephedrine on the expression levels of brain-derived neurotropic factor (BDNF) and postsynaptic density protein 95 (PSD95) and synapsin1 in PC12 cells, and to explore the mechanism of ephedrine cytotoxicity on ...
2021, 39(6): 534-537.
doi: 10.12206/j.issn.1006-0111.202104122
Abstract:
Objective To identify the crude drugs of Anoectochilus burmannicus, and clarify its original plant pharmacognostical and microscopic characteristics. Methods The pharmacognostical identification method was used to observe the original plant,...
2021, 39(6): 538-541, 565.
doi: 10.12206/j.issn.1006-0111.202103034
Abstract:
Objective To prepare propranolol hydrochloride loaded cubosomes (PPL-Cubs) with high entrapment efficiency. Methods PPL-Cubs was prepared by pH gradient method. Pressure and cycles of high pressure homogenization, dosage of glyceryl monooleate...
2021, 39(6): 542-548.
doi: 10.12206/j.issn.1006-0111.202108089
Abstract:
Objective To investigate the taxonomic structure and diversity of endophytic fungi from Cynanchum bungei Decne., explore the potential microbial resources and functions and provide the theoretical basis for new antitumor endophytic fungi. Method...
2021, 39(6): 549-551, 576.
doi: 10.12206/j.issn.1006-0111.202009046
Abstract:
Objective To optimize the manufacture process for Zhibai Anshen oral liquid. Methods The orthogonal designed experiments were conducted to monitor the effects of three factors on the content of mangiferin. The three factors included the amount ...
2021, 39(6): 552-556.
doi: 10.12206/j.issn.1006-0111.202103043
Abstract:
Objective To explore the role of clinical pharmacists in rational drug use through the pharmacy care of an elderly pneumonia patient with Chlamydia psittaci infection and drug-induced liver injury. Methods The clinical pharmacists participate...
2021, 39(6): 557-560.
doi: 10.12206/j.issn.1006-0111.202101002
Abstract:
Objective To evaluate the clinical value of compound bone peptide injection in patients with thoracolumbar osteoporotic fracture. Methods 96 patients admitted from January 2018 to January 2020 with thoracolumbar osteoporotic fracture were selec...
2021, 39(6): 561-565.
doi: 10.12206/j.issn.1006-0111.202105099
Abstract:
Objective To compare the clinical effects of interscalene brachial plexus block and superior trunk block in arthroscopic shoulder surgery with 0.25% ropivacaine. Methods 46 patients undergoing shoulder arthroscopy surgery were included and ran...
2021, 39(6): 566-568.
doi: 10.12206/j.issn.1006-0111.202103017
Abstract:
Objective To explore the role of clinical pharmacists in the treatment of drug poisoning by analyzing the clinical pharmacist's participation in the treatment of a patient with sodium valproate poisoning. Methods Clinical pharmacists measured ...
2021, 39(6): 569-572.
doi: 10.12206/j.issn.1006-0111.202103027
Abstract:
Objective To investigate the relationship between cystatin C level and the plasma trough concentration of teicoplanin, so as to provide a reference for the rational application of teicoplanin in clinical practice. Methods The clinical data of ...
2021, 39(6): 573-576.
doi: 10.12206/j.issn.1006-0111.202101023
Abstract:
Objective To analyze the current situation of off-label drug use for tic disorder in a tertiary maternity and child hospital, so as to promote clinical safe and rational drug use. Methods Through the hospital information system, the pediatric ...
2021, 39(6): 577-580.
doi: 10.12206/j.issn.1006-0111.202104086
Abstract:
Objective To evaluate the cognition, attitude, and barriers of family doctor team members in chongming district of Shanghai to pharmacists joining the team and providing community pharmaceutical care. To provide the reference resources for the esta...
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