2020 Vol. 38, No. 5
Display Method:
2020, 38(5): 385-397.
doi: 10.12206/j.issn.1006-0111.202005020
Abstract:
Coronavirus infection seriously threatens human health. There is no specific medication or vaccine so far. In recent years, domestic and foreign researchers have developed a variety of small-molecule inhibitors against the ligand S protein, RdRp, PLp...
Coronavirus infection seriously threatens human health. There is no specific medication or vaccine so far. In recent years, domestic and foreign researchers have developed a variety of small-molecule inhibitors against the ligand S protein, RdRp, PLp...
2020, 38(5): 398-403, 422.
doi: 10.12206/j.issn.1006-0111.202005042
Abstract:
The corona virus disease 2019 (COVID-19) has recently become pandemic and is still spreading. Many severe or critical COVID-19 cases meet the diagnostic criteria of sepsis and septic shock in the clinical manifestations. It is important to study the ...
The corona virus disease 2019 (COVID-19) has recently become pandemic and is still spreading. Many severe or critical COVID-19 cases meet the diagnostic criteria of sepsis and septic shock in the clinical manifestations. It is important to study the ...
2020, 38(5): 404-408, 434.
doi: 10.12206/j.issn.1006-0111.202005040
Abstract:
Objective To investigate the characteristics of the adverse drug reaction (ADR) in the traditional Chinese medicine (TCM) treatment followed the "COVID-19 Diagnosis and Treatment Program (trial version 7)" during the medical observation period, and...
2020, 38(5): 409-412.
doi: 10.12206/j.issn.1006-0111.202004035
Abstract:
Cuscuta chinensis is a commonly used traditional Chinese herbal medicine. Cuscuta chinensis has a long history of clinical application in the treatment of varieties of ocular diseases. This review summarized the literatures related to its clinical ap...
Cuscuta chinensis is a commonly used traditional Chinese herbal medicine. Cuscuta chinensis has a long history of clinical application in the treatment of varieties of ocular diseases. This review summarized the literatures related to its clinical ap...
2020, 38(5): 413-417, 430.
doi: 10.12206/j.issn.1006-0111.202004050
Abstract:
Objective To study the action of kaempferol (KAE) against Candida albicans biofilms and explore the potential mechanisms. Methods B iofilm metabolic activity assay was used to investigate the action of KAE against C. albicans biofilm formation as w...
2020, 38(5): 418-422.
doi: 10.12206/j.issn.1006-0111.202001071
Abstract:
Objective To discover the medicinal active molecules from the fermentation extract of sponge-symbiotic Streptomyces sp. LHW2432. Methods Compounds were isolated and purified from the fermentation extract of LHW2432 by silica gel, ODS chromatogr...
2020, 38(5): 423-430.
doi: 10.12206/j.issn.1006-0111.202003073
Abstract:
Objective To analyze and identify the chemical components in the Nocardia rubra cell wall skeleton (Nr-CWS), and to determine the contents of monosaccharides accurately. Methods The extract of Nr-CWS was separated and analyzed by UHPLC-Q-TOF/MS...
Effects of compound Ziyin granule on sex hormones and oxidative stress levels of ovariectomized rats
2020, 38(5): 431-434.
doi: 10.12206/j.issn.1006-0111.201912023
Abstract:
Objective To investigate the effect of compound Ziyin granule (CZG) on sex hormones and oxidative stress levels of ovariectomized rats. Methods The experiment was divided into model group, Liuwei Dihuang pill group, estradiol valerate group, Zi...
2020, 38(5): 435-440.
doi: 10.12206/j.issn.1006-0111.202003127
Abstract:
Objective To investigate the potential mechanism of Rhizoma Coptidis extracts (RCE) against sepsis associated with acute kidney injury. Methods C57BL/6 mice were divided into sham group, model group and RCE treatment group. The levels of Scr an...
2020, 38(5): 441-446, 457.
doi: 10.12206/j.issn.1006-0111.201910022
Abstract:
Objective To evaluate the effects of different solubilizing techniques on the in vitro dissolution and in vivo pharmacokinetics of Sirolimus (SRL). Methods Solid dispersions (SD), inclusion complex (IC), self-micro emulsifying drug delivery sys...
2020, 38(5): 447-450.
doi: 10.12206/j.issn.1006-0111.202003188
Abstract:
Objective To establish the best wine steaming process for morinda officinalis with monotropein as indicator. Methods Response surface methodology was used to optimize the wine steaming process for morinda officinalis with the amount of rice win...
2020, 38(5): 451-457.
doi: 10.12206/j.issn.1006-0111.202004105
Abstract:
Objective To evaluate the developmental toxicity and genotoxicity of leonurine. Methods Leonurine was given orally to SD pregnant rats on the 6th to 15th day of pregnancy at the dose of 500, 1 000 and 2 000 mg/kg body weight. The control group ...
2020, 38(5): 458-461.
doi: 10.12206/j.issn.1006-0111.202004115
Abstract:
Objective To verify the feasibility and maneuverability of fast bare-handed vertical slicing method for dry Chinese herbal medicine, and to provide reference of this method for different types of medicinal materials. Methods S everal representative...
2020, 38(5): 462-465.
doi: 10.12206/j.issn.1006-0111.202002059
Abstract:
Objective To establish a method for simultaneous determination of chlorogenic acid, luteolin-7-O-β-D-glucoside,3,5-dicaffeoylquinic acid, linarin and pogostone in Fangshu Qingre mixture by RP-HPLC. Methods ZORBAX-SB-C18 column(4.6 mm×250 mm, 5 ...
2020, 38(5): 466-468, 480.
doi: 10.12206/j.issn.1006-0111.202003033
Abstract:
Objective To investigate the extraction methods for active components from oral ulcer film and optimize the determination methods of active components dexamethasone sodium phosphate and metronazole. Methods Different extraction solvents(methano...
2020, 38(5): 469-475.
doi: 10.12206/j.issn.1006-0111.202003080
Abstract:
Objective To introduce the improvements of multi-mode outpatient pharmacy services based on the new medical reform policy. Methods The pharmacist’s roles, responsibilities, working procedures and the achievements were discussed. Results and c...
2020, 38(5): 476-480.
doi: 10.12206/j.issn.1006-0111.201912161
Abstract:
Objective To improve laboratory research of generic drugs in Chinese pharmaceutical enterprises, avoid the defects in the research process, and explore the feasibility of six sigma management (DMAIC) as improvement model in the process of generic d...
Contribution System
Author Login
Review Login
Editor Login
Reader Login
News