2020 Vol. 38, No. 6
Display Method:
2020, 38(6): 481-484.
doi: 10.12206/j.issn.1006-0111.202003055
Abstract:
COVID-19 patients infected with SARS-CoV-2 showed different degrees of liver injury. A series of studies have shown that cytokine storm, bile duct cell injury caused by SARS-CoV-2 and drug-induced hepatotoxicity can induce secondary liver injury. Thi...
COVID-19 patients infected with SARS-CoV-2 showed different degrees of liver injury. A series of studies have shown that cytokine storm, bile duct cell injury caused by SARS-CoV-2 and drug-induced hepatotoxicity can induce secondary liver injury. Thi...
2020, 38(6): 485-491, 538.
doi: 10.12206/j.issn.1006-0111.202005078
Abstract:
Objective To investigate the active ingredients of Jingfang Baidu San for the prevention and treatment of COVID-19 by using network pharmacology and molecular docking, and to provide references for clinical applications. Methods T he chemical const...
2020, 38(6): 492-495.
doi: 10.12206/j.issn.1006-0111.202007063
Abstract:
Humulus lupulus is a kind of special resource plant used both as medicine and food in Xinjiang. In addition to being widely used in beer brewing, Humulus lupulus has long been recognized for its medicinal value, especially for the treatment of postme...
Humulus lupulus is a kind of special resource plant used both as medicine and food in Xinjiang. In addition to being widely used in beer brewing, Humulus lupulus has long been recognized for its medicinal value, especially for the treatment of postme...
2020, 38(6): 496-500, 567.
doi: 10.12206/j.issn.1006-0111.202006061
Abstract:
Type 2 diabetes is a high risk factor for atherosclerotic cardiovascular disease. Studies have found that SGLT-2 inhibitor and GLP-1 receptor agonists have cardiovascular protective effects in patients with type 2 diabetes and cardiovascular disease....
Type 2 diabetes is a high risk factor for atherosclerotic cardiovascular disease. Studies have found that SGLT-2 inhibitor and GLP-1 receptor agonists have cardiovascular protective effects in patients with type 2 diabetes and cardiovascular disease....
2020, 38(6): 501-505.
doi: 10.12206/j.issn.1006-0111.202007031
Abstract:
Colorectal cancer is a malignant tumor with increasing incidence in China. Chemotherapy or neoadjuvant therapy are needed when the patients have deep tumor invasion of distant metastasis due to the hidden clinical manifestations and limited screening...
Colorectal cancer is a malignant tumor with increasing incidence in China. Chemotherapy or neoadjuvant therapy are needed when the patients have deep tumor invasion of distant metastasis due to the hidden clinical manifestations and limited screening...
2020, 38(6): 506-508, 542.
doi: 10.12206/j.issn.1006-0111.201908127
Abstract:
Objective To design, synthesize and measure antifungal activities of galloyl piperazine derivatives. Methods Trimethoxyl gallic acid was used as starting material, reacted with piperazine in the presence of PyBOP/DIEA to afford the intermediate...
2020, 38(6): 509-515.
doi: 10.12206/j.issn.1006-0111.202008078
Abstract:
Objective To optimize the extraction process of collagen from the jellyfish (Nemopilema nomurai) and explore its characters. Methods T he collagen was extracted with acetic acid and pepsin from jellyfish. The crude jellyfish collagen was purified b...
2020, 38(6): 516-522.
doi: 10.12206/j.issn.1006-0111.202006002
Abstract:
Objective To explore the possible mechanism of activating blood circulation and removing blood stasis herbs in the treatment of endometriosis (EM) with network pharmacology approach. Methods S even kinds of commonly used activating blood circulatio...
2020, 38(6): 523-527.
doi: 10.12206/j.issn.1006-0111.202005047
Abstract:
Objective To investigate the protective effect of menatetrenone (MK4) on the osteoblasts in oxidative stress, and to clarify the anti-osteoporosis mechanism of MK4. Methods M ouse osteoblasts (MC3T3-E1) induced by hydrogen peroxide (H2O2) was used....
2020, 38(6): 528-532.
doi: 10.12206/j.issn.1006-0111.202007015
Abstract:
Objective To investigate the anti-inflammatory and analgesic effects of the active fractions of Tongfeng granules on rats with arthritis induced by complete Freund's adjuvant. Methods 5 6 SD rats were randomly divided into seven groups, blank group...
2020, 38(6): 533-538.
doi: 10.12206/j.issn.1006-0111.202004089
Abstract:
Objective To evaluate the genetic toxicity of Wentilactone A. Methods The classical genotoxicity test combination (Ames test, in vitro CHO cell chromosome aberration test and mouse bone marrow micronucleus test) was used to detect the genotoxic...
2020, 38(6): 539-542.
doi: 10.12206/j.issn.1006-0111.202004077
Abstract:
Objective In order to solve the obvious adverse reactions of ribavirin, to develop ribavirin liposome inhalation powder and to evaluate its quality characteristics. Methods T he ribavirin liposomes were prepared by the thin film dispersion method, ...
2020, 38(6): 543-546.
doi: 10.12206/j.issn.1006-0111.202003040
Abstract:
Objective To establish a two-dimensional high-performance liquid chromatography method for the determination of tigecycline in human cerebrospinal fluid, which can be used for the drug monitoring in patients with intracranial infection. Methods ...
2020, 38(6): 547-551.
doi: 10.12206/j.issn.1006-0111.202003184
Abstract:
Objective To establish an assay method for unbound teicoplanin in plasma by centrifugal ultrafiltration combined with ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Methods P rotein was removed from plasma by a Centr...
2020, 38(6): 552-557.
doi: 10.12206/j.issn.1006-0111.202008069
Abstract:
Objective To investigate the overall incidence and risk of hypertension in the treatment of cancer patients who receive anlotinib and compare the differences between anlotinib and other VEGFR inhibitors. Methods P ubmed, Embase, Cochrane Library, A...
2020, 38(6): 558-562.
doi: 10.12206/j.issn.1006-0111.202007073
Abstract:
Objective To review and analysis the clinical manifestations, occurrence rules, treatment and outcomes of adverse drug reactions caused by anlotinib in order to provide reference for safety and reasonable use of anlotinib in clinical practice. Meth...
2020, 38(6): 563-567.
doi: 10.12206/j.issn.1006-0111.201911056
Abstract:
Objective To improve the quality for authorized distribution of traditional Chinese medicine pieces, reduce patient complaints and increase patient satisfaction. Methods Patient’s complaints against different drug dispensing modes were analyzed...
2020, 38(6): 568-573.
doi: 10.12206/j.issn.1006-0111.202003200
Abstract:
Objective To provide data reference for improving the selection criteria of the dosage forms and specifications of the electrolytes and antipyretic analgesics in the Essential Medicines List, and to improve the applicability of these medicines to ch...
2020, 38(6): 574-576.
doi: 10.12206/j.issn.1006-0111.202002088
Abstract:
Objective To explore the effect of the intervention of clinical pharmacists on the rational use of piperacillin-tazobactam by using PDCA cycle, in order to provide reference for rational drug use. Methods T he problems of piperacillin-tazobactam in...
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