2018 Vol. 36, No. 4
Display Method:
2018, 36(4): 289-292.
doi: 10.3969/j.issn.1006-0111.2018.04.001
Abstract:
Dexmedetomidine(Dex) is a specific alpha-2-adrenergic agonist which was widely used in nerve blocks as an adjuvant to local anesthetic(LA) in order to shortening the onset time, prolonging the analgesic effect and reducing the postoperative analgesic...
Dexmedetomidine(Dex) is a specific alpha-2-adrenergic agonist which was widely used in nerve blocks as an adjuvant to local anesthetic(LA) in order to shortening the onset time, prolonging the analgesic effect and reducing the postoperative analgesic...
2018, 36(4): 293-296.
doi: 10.3969/j.issn.1006-0111.2018.04.002
Abstract:
Ischemic stroke is one of the leading causes of permanent disability in the elderly with high prevalence rate. The therapy window of current treatment is relatively short. Finding an effective treatment for ischemic stroke is the key point of researc...
Ischemic stroke is one of the leading causes of permanent disability in the elderly with high prevalence rate. The therapy window of current treatment is relatively short. Finding an effective treatment for ischemic stroke is the key point of researc...
2018, 36(4): 297-300.
doi: 10.3969/j.issn.1006-0111.2018.04.003
Abstract:
Patients with diabetes have higher risks of depression that may adversely affect subjective well-being and quality of life, and may increase the non-compliance of glycemic control. Depression in diabetic patients can be effectively relieved by psycho...
Patients with diabetes have higher risks of depression that may adversely affect subjective well-being and quality of life, and may increase the non-compliance of glycemic control. Depression in diabetic patients can be effectively relieved by psycho...
2018, 36(4): 301-306,328.
doi: 10.3969/j.issn.1006-0111.2018.04.004
Abstract:
Polyethylene glycol and its derivatives are widely used in protein drug modification due to the excellent hydrophilicity, biocompatibility and bioinertia. The pegylation makes it possible that protein has lower immunogenicity and longer half-life. PE...
Polyethylene glycol and its derivatives are widely used in protein drug modification due to the excellent hydrophilicity, biocompatibility and bioinertia. The pegylation makes it possible that protein has lower immunogenicity and longer half-life. PE...
2018, 36(4): 307-312,350.
doi: 10.3969/j.issn.1006-0111.2018.04.005
Abstract:
As the carrier of antitumor drugs, nanoparticles have many advantages, such as improving drug targeting, enhancing stability and reducing drug toxicity. In recent years, studies on anticancer drug nanoparticles have made great progress. This paper re...
As the carrier of antitumor drugs, nanoparticles have many advantages, such as improving drug targeting, enhancing stability and reducing drug toxicity. In recent years, studies on anticancer drug nanoparticles have made great progress. This paper re...
2018, 36(4): 313-317.
doi: 10.3969/j.issn.1006-0111.2018.04.006
Abstract:
Objective To evaluate the protective effect of Qifu decoction (QFD) on adriamycin-induced cardiac injury based on GC-MS serum metabolomics and explore its mechanism. Methods Twenty-four rats were randomly divided into three groups:control group, A...
Objective To evaluate the protective effect of Qifu decoction (QFD) on adriamycin-induced cardiac injury based on GC-MS serum metabolomics and explore its mechanism. Methods Twenty-four rats were randomly divided into three groups:control group, A...
2018, 36(4): 318-323.
doi: 10.3969/j.issn.1006-0111.2018.04.007
Abstract:
Objective To study the effect of cyclopamine on liver regeneration, and to explore its possible molecular mechanism. Methods iTRAQ-based quantitative proteomics combined with 2D liquid chromatography-tandem mass spectrometry were applied to study ...
Objective To study the effect of cyclopamine on liver regeneration, and to explore its possible molecular mechanism. Methods iTRAQ-based quantitative proteomics combined with 2D liquid chromatography-tandem mass spectrometry were applied to study ...
2018, 36(4): 324-328.
doi: 10.3969/j.issn.1006-0111.2018.04.008
Abstract:
Objective To establish HPLC fingerprint for water soluble components and assay gallic acid, chlorogenic acid, naringin, aurantiamarin in Qingzhiweizuocan Tea, Methods High Performance Liquid Chromatography(HPLC) analysis was performed on Kromasil ...
Objective To establish HPLC fingerprint for water soluble components and assay gallic acid, chlorogenic acid, naringin, aurantiamarin in Qingzhiweizuocan Tea, Methods High Performance Liquid Chromatography(HPLC) analysis was performed on Kromasil ...
2018, 36(4): 329-333,354.
doi: 10.3969/j.issn.1006-0111.2018.04.009
Abstract:
Objective To optimize the alcohol precipitation process of compound Yinchen mixture by central composite design-response surface method. Methods With the transfer rates of geniposide and solid removal rate as comprehensive evaluation index, the ef...
Objective To optimize the alcohol precipitation process of compound Yinchen mixture by central composite design-response surface method. Methods With the transfer rates of geniposide and solid removal rate as comprehensive evaluation index, the ef...
2018, 36(4): 334-337.
doi: 10.3969/j.issn.1006-0111.2018.04.010
Abstract:
Objective To establish a double wavelength method for the simultaneous determination of ligustrazine hydrochloride, chlorogenic acid, ferulic acid, stibene glucoside, Lignin glycosides, asperosaponin Ⅵ and schizandrol A in compound caulis polygoni m...
Objective To establish a double wavelength method for the simultaneous determination of ligustrazine hydrochloride, chlorogenic acid, ferulic acid, stibene glucoside, Lignin glycosides, asperosaponin Ⅵ and schizandrol A in compound caulis polygoni m...
2018, 36(4): 338-342.
doi: 10.3969/j.issn.1006-0111.2018.04.011
Abstract:
Objective To study the effectiveness of Gutong Plaster for the treatment of Rheumatoid arthritis joint pain with Cold dampness syndrome based on RCT. Methods 140 cases of RA patients were randomly divided into blank group (n=40), test group (n=50)...
Objective To study the effectiveness of Gutong Plaster for the treatment of Rheumatoid arthritis joint pain with Cold dampness syndrome based on RCT. Methods 140 cases of RA patients were randomly divided into blank group (n=40), test group (n=50)...
2018, 36(4): 343-346.
doi: 10.3969/j.issn.1006-0111.2018.04.012
Abstract:
Objective To revise and improve the quality standard for Fenghan Shiling San. Methods The thin layer chromatography was used to identify euphorbiae ebracteolatae radix, angelicae dahuricae radix, notoginseng radix et rhizome, radix paeoniae rubra ...
Objective To revise and improve the quality standard for Fenghan Shiling San. Methods The thin layer chromatography was used to identify euphorbiae ebracteolatae radix, angelicae dahuricae radix, notoginseng radix et rhizome, radix paeoniae rubra ...
2018, 36(4): 347-350.
doi: 10.3969/j.issn.1006-0111.2018.04.013
Abstract:
Objective To establish an HPLC method for simultaneously determination of daidzin and its metabolite in rat intestinal bacteria test solution in vitro, and study the metabolism of daidzin by rat intestinal bacteria. Methods The incubation of daidz...
Objective To establish an HPLC method for simultaneously determination of daidzin and its metabolite in rat intestinal bacteria test solution in vitro, and study the metabolism of daidzin by rat intestinal bacteria. Methods The incubation of daidz...
2018, 36(4): 351-354.
doi: 10.3969/j.issn.1006-0111.2018.04.014
Abstract:
Objective To search for the most effective condition of extracting quercetin from Semen Plantaginis. Methods Single factor experiments of extracting quercetin from Litchi Semen Plantaginis were carried out by HPLC. Ultrasonic power,extracting time...
Objective To search for the most effective condition of extracting quercetin from Semen Plantaginis. Methods Single factor experiments of extracting quercetin from Litchi Semen Plantaginis were carried out by HPLC. Ultrasonic power,extracting time...
2018, 36(4): 355-357.
doi: 10.3969/j.issn.1006-0111.2018.04.015
Abstract:
Objective To establish a method of HPLC for the determination of ephedrine hydrochloride and pseudoephedrine hydrochloride in Maxing Kanggan Granules. Methods Wondasil C18(4.6 mm×250 mm,5 μm)was used at 30℃ and the acetonitrile-0.1% H3PO4 (5:95 ) ...
Objective To establish a method of HPLC for the determination of ephedrine hydrochloride and pseudoephedrine hydrochloride in Maxing Kanggan Granules. Methods Wondasil C18(4.6 mm×250 mm,5 μm)was used at 30℃ and the acetonitrile-0.1% H3PO4 (5:95 ) ...
2018, 36(4): 358-361,368.
doi: 10.3969/j.issn.1006-0111.2018.04.016
Abstract:
Objective To investigate the anti-inflammatory chemical constituents from the stem of Ilex cornuta Lindl.et Paxt. Methods The 80% EtOH extract of the stem of Ilex cornuta was purified by macro-porous adsorption resin chromatography,positive and ne...
Objective To investigate the anti-inflammatory chemical constituents from the stem of Ilex cornuta Lindl.et Paxt. Methods The 80% EtOH extract of the stem of Ilex cornuta was purified by macro-porous adsorption resin chromatography,positive and ne...
2018, 36(4): 362-364,384.
doi: 10.3969/j.issn.1006-0111.2018.04.017
Abstract:
Objective To establish a method of analysis for glycine and lysis hydrochloride in human coagulation factor Ⅷ by pre-column derivation HPLC. Methods The sample was derivatized with 2,4-dinitrofluorobenzene(DNFB). HPLC was performed on a C18 column...
Objective To establish a method of analysis for glycine and lysis hydrochloride in human coagulation factor Ⅷ by pre-column derivation HPLC. Methods The sample was derivatized with 2,4-dinitrofluorobenzene(DNFB). HPLC was performed on a C18 column...
Analysis and pharmaceutical care of the adverse reaction of cyclosporine induced by drug interaction
2018, 36(4): 365-368.
doi: 10.3969/j.issn.1006-0111.2018.04.018
Abstract:
Objective To explore the role of clinical pharmacists in the clinical judgment and treatment of adverse drug reactions induced by drug interactions. Methods The correlation between cyclosporine and adverse effects of tremor in two hands were inves...
Objective To explore the role of clinical pharmacists in the clinical judgment and treatment of adverse drug reactions induced by drug interactions. Methods The correlation between cyclosporine and adverse effects of tremor in two hands were inves...
2018, 36(4): 369-372.
doi: 10.3969/j.issn.1006-0111.2018.04.019
Abstract:
Objective To discuss the risk factors affecting the metabolism of valproic acid (VPA),improve the rational medication and reduce the rate of epilepsy recurrence. Methods Two hospitalized patients were analyzed after being administrated VPA for epi...
Objective To discuss the risk factors affecting the metabolism of valproic acid (VPA),improve the rational medication and reduce the rate of epilepsy recurrence. Methods Two hospitalized patients were analyzed after being administrated VPA for epi...
2018, 36(4): 373-378.
doi: 10.3969/j.issn.1006-0111.2018.04.020
Abstract:
Objective To evaluate the efficacy and safety of oxcarbazepine and carbamazepine in treating post-stroke epilepsy. Methods PubMed, Cochrane Library, EMbase, VIP, CNKI and CBM were used for searching literatures related to oxcarbazepine and carbama...
Objective To evaluate the efficacy and safety of oxcarbazepine and carbamazepine in treating post-stroke epilepsy. Methods PubMed, Cochrane Library, EMbase, VIP, CNKI and CBM were used for searching literatures related to oxcarbazepine and carbama...
2018, 36(4): 379-384.
doi: 10.3969/j.issn.1006-0111.2018.04.021
Abstract:
Objective Systematic evaluation of effectiveness and safety of amphotericin B bladder irrigation in urinary tract fungal infection. Methods Cross-sectional or controlled studies of amphotericin B bladder irrigation in the treatment of urinary trac...
Objective Systematic evaluation of effectiveness and safety of amphotericin B bladder irrigation in urinary tract fungal infection. Methods Cross-sectional or controlled studies of amphotericin B bladder irrigation in the treatment of urinary trac...
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