2018 Vol. 36, No. 3
Display Method:
2018, 36(3): 193-197.
doi: 10.3969/j.issn.1006-0111.2018.03.001
Abstract:
Depression is a serious health hazard and the World Health Organization predicts that depression will be the second leading cause of abnormal death and disability by 2020. Currently, most antidepressants are tricyclic antidepressants (TCA), tetracycl...
Depression is a serious health hazard and the World Health Organization predicts that depression will be the second leading cause of abnormal death and disability by 2020. Currently, most antidepressants are tricyclic antidepressants (TCA), tetracycl...
2018, 36(3): 198-203.
doi: 10.3969/j.issn.1006-0111.2018.03.002
Abstract:
In recent years,the incidences of depression increased year by year due to increased social pressure,which do serious harm to human being both physically and mentally.Studies have shown that the pathogenesis of depression is complicated,mainly relate...
In recent years,the incidences of depression increased year by year due to increased social pressure,which do serious harm to human being both physically and mentally.Studies have shown that the pathogenesis of depression is complicated,mainly relate...
2018, 36(3): 204-209,214.
doi: 10.3969/j.issn.1006-0111.2018.03.003
Abstract:
Sinomenine is an alkaloid found in the climbing plant Sinomenium acutum.Structurally, it belongs to the isoquinoline derivatives, which have various bioactivities.Clinically, it is used in the treatment for rheumatism, rheumatoid arthritis and arrhyt...
Sinomenine is an alkaloid found in the climbing plant Sinomenium acutum.Structurally, it belongs to the isoquinoline derivatives, which have various bioactivities.Clinically, it is used in the treatment for rheumatism, rheumatoid arthritis and arrhyt...
2018, 36(3): 210-214.
doi: 10.3969/j.issn.1006-0111.2018.03.004
Abstract:
Objective To propose scalable moving-window similarity combined with Bayesian for rapid discriminating low active pharmaceutical ingredient (API) signal drugs (LAPIDs). Methods The scalable moving-window similarity method was employed by setting t...
Objective To propose scalable moving-window similarity combined with Bayesian for rapid discriminating low active pharmaceutical ingredient (API) signal drugs (LAPIDs). Methods The scalable moving-window similarity method was employed by setting t...
2018, 36(3): 215-218,223.
doi: 10.3969/j.issn.1006-0111.2018.03.005
Abstract:
Objective To study the mechanism of bioadhesive materials (Chitosan, Carbomer and hydroxypropyl methyl cellulose(HPMC)) on promoting panax notoginseng saponins(PNS)'s oral absorption by microarray. Methods The study was divided into four groups.PN...
Objective To study the mechanism of bioadhesive materials (Chitosan, Carbomer and hydroxypropyl methyl cellulose(HPMC)) on promoting panax notoginseng saponins(PNS)'s oral absorption by microarray. Methods The study was divided into four groups.PN...
2018, 36(3): 219-223.
doi: 10.3969/j.issn.1006-0111.2018.03.006
Abstract:
Objective To evaluate the anti-osteoporotic effect of xanthohumol (XN) in animal and osteoblast. Methods The anti-osteoporotic study on XN was performed with ovariectomized mice model. Serum biochemical indexes, bone mineral density (BMD) and bone...
Objective To evaluate the anti-osteoporotic effect of xanthohumol (XN) in animal and osteoblast. Methods The anti-osteoporotic study on XN was performed with ovariectomized mice model. Serum biochemical indexes, bone mineral density (BMD) and bone...
2018, 36(3): 224-227,273.
doi: 10.3969/j.issn.1006-0111.2018.03.007
Abstract:
Objective To establish a reversed phase high performance liquid chromatography method which couldb be applied to determine the content of paclitaxel stearate(PTX-SA)and its bioactive metabolites paclitaxel(PTX)simultaneously. Methods Diazepam was c...
Objective To establish a reversed phase high performance liquid chromatography method which couldb be applied to determine the content of paclitaxel stearate(PTX-SA)and its bioactive metabolites paclitaxel(PTX)simultaneously. Methods Diazepam was c...
2018, 36(3): 228-233.
doi: 10.3969/j.issn.1006-0111.2018.03.008
Abstract:
Objective To observe the effect of salted processing on the contents of total alismol, 24-acetylalisol A and 23-acetylalisol B in Alisma Rhizoma. Methods UV was used for the determination of total alismol's content in crude Alisma Rhizoma and salt...
Objective To observe the effect of salted processing on the contents of total alismol, 24-acetylalisol A and 23-acetylalisol B in Alisma Rhizoma. Methods UV was used for the determination of total alismol's content in crude Alisma Rhizoma and salt...
2018, 36(3): 234-237,273.
doi: 10.3969/j.issn.1006-0111.2018.03.009
Abstract:
Illicium henryi Diels is a medicinal and aromatic plant native to China with Chinese name Mancao or Honduhui. The name of Mancao was first recorded in the "Classic of Mountains and Rivers" and the earliest documented medicinal function of this plant ...
Illicium henryi Diels is a medicinal and aromatic plant native to China with Chinese name Mancao or Honduhui. The name of Mancao was first recorded in the "Classic of Mountains and Rivers" and the earliest documented medicinal function of this plant ...
2018, 36(3): 238-242.
doi: 10.3969/j.issn.1006-0111.2018.03.010
Abstract:
Objective To investigate the effects on myocardial mitochondria-related indexes in rats after rapid elevation to 3 400 m altitude and myocardial protection effects with metoprolol. Methods Male Wistar rats were randomly divided into three groups w...
Objective To investigate the effects on myocardial mitochondria-related indexes in rats after rapid elevation to 3 400 m altitude and myocardial protection effects with metoprolol. Methods Male Wistar rats were randomly divided into three groups w...
2018, 36(3): 243-246.
doi: 10.3969/j.issn.1006-0111.2018.03.011
Abstract:
Objective To investigate the anti-hypoxia effects of octacosane and the petroleum ether extract from Saussurea Involucrate (PESI) on the water, sugar, lipid and protein metabolism of mice at simulated high altitude. Methods The healthy adult male ...
Objective To investigate the anti-hypoxia effects of octacosane and the petroleum ether extract from Saussurea Involucrate (PESI) on the water, sugar, lipid and protein metabolism of mice at simulated high altitude. Methods The healthy adult male ...
2018, 36(3): 247-249,254.
doi: 10.3969/j.issn.1006-0111.2018.03.012
Abstract:
Objective To study pharmacodynamics of the effective anti-hypoxia components in the petroleum ether extract of Saussurea Involucrate (PESI) and octacosane. Methods PESI and octacosane were first evaluated by normobaric hypoxia model, acute decompr...
Objective To study pharmacodynamics of the effective anti-hypoxia components in the petroleum ether extract of Saussurea Involucrate (PESI) and octacosane. Methods PESI and octacosane were first evaluated by normobaric hypoxia model, acute decompr...
2018, 36(3): 250-254.
doi: 10.3969/j.issn.1006-0111.2018.03.013
Abstract:
Objective To investigate the effect of hypoxia with cold on the heart and brain damage in rats by simulating 6 000 m high altitude at different exposure time, established a rat model of acute mountain sickness for the related mechanism studies. Met...
Objective To investigate the effect of hypoxia with cold on the heart and brain damage in rats by simulating 6 000 m high altitude at different exposure time, established a rat model of acute mountain sickness for the related mechanism studies. Met...
2018, 36(3): 255-259.
doi: 10.3969/j.issn.1006-0111.2018.03.014
Abstract:
Objective To investigate anti-hypoxia activity and protective effects of Lishukang capsule on rat brain tissue at simulated high altitude hypoxia. Methods The anti-hypoxic activity of Lishukang capsule was evaluated with normobaric hypoxia test an...
Objective To investigate anti-hypoxia activity and protective effects of Lishukang capsule on rat brain tissue at simulated high altitude hypoxia. Methods The anti-hypoxic activity of Lishukang capsule was evaluated with normobaric hypoxia test an...
2018, 36(3): 260-264,281.
doi: 10.3969/j.issn.1006-0111.2018.03.015
Abstract:
Objective To evaluate the efficacy and safety of donepezil combined with memantine in the treatment of Alzheimer's disease and provide a guidance for the proper clinical use of those medications. Methods The literatures published from 2014 to 2016...
Objective To evaluate the efficacy and safety of donepezil combined with memantine in the treatment of Alzheimer's disease and provide a guidance for the proper clinical use of those medications. Methods The literatures published from 2014 to 2016...
2018, 36(3): 265-269,288.
doi: 10.3969/j.issn.1006-0111.2018.03.016
Abstract:
Objective To establish the quality standard for Xiangsu Weitong capsule. Methods Radixet rhizoma glycyrrhizae,rhizoma corydalis,poria,rhizoma cyperi were identified by TLC and the contents of baicalin were determined by RP-HPLC. Chromatography con...
Objective To establish the quality standard for Xiangsu Weitong capsule. Methods Radixet rhizoma glycyrrhizae,rhizoma corydalis,poria,rhizoma cyperi were identified by TLC and the contents of baicalin were determined by RP-HPLC. Chromatography con...
2018, 36(3): 270-273.
doi: 10.3969/j.issn.1006-0111.2018.03.017
Abstract:
Objective To investigate the hydrophilic chemical constituents from Thesium Chinensis Turcz. Methods The water extract of Thesium Chinensis Turcz. was adsorbed onto AB-8 resin column and eluted with 50% ethanol to give the hydrophilic portion TT50...
Objective To investigate the hydrophilic chemical constituents from Thesium Chinensis Turcz. Methods The water extract of Thesium Chinensis Turcz. was adsorbed onto AB-8 resin column and eluted with 50% ethanol to give the hydrophilic portion TT50...
2018, 36(3): 274-276.
doi: 10.3969/j.issn.1006-0111.2018.03.018
Abstract:
Objective To develop a new method to determine the contents of rutaecarpine in Fuzhengpingxiao capsule by HPLC method. Methods Samples were handled by ethanol and extraction with ethyl acetate. The separation was achieved on an Agilent TC-C18 colu...
Objective To develop a new method to determine the contents of rutaecarpine in Fuzhengpingxiao capsule by HPLC method. Methods Samples were handled by ethanol and extraction with ethyl acetate. The separation was achieved on an Agilent TC-C18 colu...
2018, 36(3): 277-281.
doi: 10.3969/j.issn.1006-0111.2018.03.019
Abstract:
Objective To prepare the sunscreen lipstick in order to prevent UVA and UVB. Methods The ratio of beeswax, castor oil and liquid paraffin were optimized with the orthogonal test based on viscosity and heat resistance. The spreadable ability, stabi...
Objective To prepare the sunscreen lipstick in order to prevent UVA and UVB. Methods The ratio of beeswax, castor oil and liquid paraffin were optimized with the orthogonal test based on viscosity and heat resistance. The spreadable ability, stabi...
2018, 36(3): 282-284.
doi: 10.3969/j.issn.1006-0111.2018.03.020
Abstract:
Objective To demonstrate the role of clinical pharmacists in nutritional support for a patient with malignant obstructive jaundice and to provide a reference for the clinical application of nutritional supplements in patients during the perioperativ...
Objective To demonstrate the role of clinical pharmacists in nutritional support for a patient with malignant obstructive jaundice and to provide a reference for the clinical application of nutritional supplements in patients during the perioperativ...
2018, 36(3): 285-288.
doi: 10.3969/j.issn.1006-0111.2018.03.021
Abstract:
Objective To discuss how the clinical pharmacists participated in the treatment of pediatric purulent meningitis and conducted drug monitoring. Methods Clinical pharmacists involved the whole process of treatment for a purulent meningitis infant w...
Objective To discuss how the clinical pharmacists participated in the treatment of pediatric purulent meningitis and conducted drug monitoring. Methods Clinical pharmacists involved the whole process of treatment for a purulent meningitis infant w...