Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

2018 Vol. 36, No. 3

Cover
Display Method:
Pathogenesis of depression and the mechanism research in TCM treatment of major depression
YAO Yuan, ZHOU Yi, ZHOU Tingting
2018, 36(3): 193-197. doi: 10.3969/j.issn.1006-0111.2018.03.001
Abstract(6425) PDF (302KB)(884)
Abstract:
Depression is a serious health hazard and the World Health Organization predicts that depression will be the second leading cause of abnormal death and disability by 2020. Currently, most antidepressants are tricyclic antidepressants (TCA), tetracycl...
Research progress in depression related biomarkers based on omics technology
LIU Shiyu, ZHAO Liang, CHEN Jun, ZHANG Guoqing
2018, 36(3): 198-203. doi: 10.3969/j.issn.1006-0111.2018.03.002
Abstract(5545) PDF (315KB)(678)
Abstract:
In recent years,the incidences of depression increased year by year due to increased social pressure,which do serious harm to human being both physically and mentally.Studies have shown that the pathogenesis of depression is complicated,mainly relate...
Research progress in sinomenine structural modification
LI Xiuzheng, ZHAO Qingjie, DONG Jiaxiao, JIANG Yunyun, YE Guangming
2018, 36(3): 204-209,214. doi: 10.3969/j.issn.1006-0111.2018.03.003
Abstract:
Sinomenine is an alkaloid found in the climbing plant Sinomenium acutum.Structurally, it belongs to the isoquinoline derivatives, which have various bioactivities.Clinically, it is used in the treatment for rheumatism, rheumatoid arthritis and arrhyt...
Drug analysis based on scalable moving-window similarity and Bayesian method by Raman spectroscopy
CHEN Xiujuan, CHEN Hui, WEI Hang, LIU Yan, LU Feng
2018, 36(3): 210-214. doi: 10.3969/j.issn.1006-0111.2018.03.004
Abstract:
Objective To propose scalable moving-window similarity combined with Bayesian for rapid discriminating low active pharmaceutical ingredient (API) signal drugs (LAPIDs). Methods The scalable moving-window similarity method was employed by setting t...
Study on effect mechanism of bioadhesive polymers on panax notoginseng saponins's absorption by microarray technology
LI Ying, ZHU Chunyan
2018, 36(3): 215-218,223. doi: 10.3969/j.issn.1006-0111.2018.03.005
Abstract:
Objective To study the mechanism of bioadhesive materials (Chitosan, Carbomer and hydroxypropyl methyl cellulose(HPMC)) on promoting panax notoginseng saponins(PNS)'s oral absorption by microarray. Methods The study was divided into four groups.PN...
Anti-osteoporotic study on xanthohumol, an active ingredient in Humulus lupulus L.
LIN Liuyue, XIA Tianshuang, JIANG Yiping, LI Changhui, QIN Luping, XIN Hailiang
2018, 36(3): 219-223. doi: 10.3969/j.issn.1006-0111.2018.03.006
Abstract:
Objective To evaluate the anti-osteoporotic effect of xanthohumol (XN) in animal and osteoblast. Methods The anti-osteoporotic study on XN was performed with ovariectomized mice model. Serum biochemical indexes, bone mineral density (BMD) and bone...
Simultaneous determination of paclitaxel-stearate (PTX-SA)and its bioactive metabolite paclitaxel (PTX)by RP-HPLC
CHENG Dan, CHEN Jianming
2018, 36(3): 224-227,273. doi: 10.3969/j.issn.1006-0111.2018.03.007
Abstract(3684) PDF (923KB)(403)
Abstract:
Objective To establish a reversed phase high performance liquid chromatography method which couldb be applied to determine the content of paclitaxel stearate(PTX-SA)and its bioactive metabolites paclitaxel(PTX)simultaneously. Methods Diazepam was c...
The effect of salted processing on the contents of main effective constituents in Alisma Rhizoma by UV and HPLC
HE Maotao, SONG Li, WEN Xia, LIU Lan
2018, 36(3): 228-233. doi: 10.3969/j.issn.1006-0111.2018.03.008
Abstract:
Objective To observe the effect of salted processing on the contents of total alismol, 24-acetylalisol A and 23-acetylalisol B in Alisma Rhizoma. Methods UV was used for the determination of total alismol's content in crude Alisma Rhizoma and salt...
Herbal textual research on Illicium lanceolatum A. C. Smith and Illicium henryi Diels
YANG Dejun, ZHOU Shilin, HUANG Baokang
2018, 36(3): 234-237,273. doi: 10.3969/j.issn.1006-0111.2018.03.009
Abstract:
Illicium henryi Diels is a medicinal and aromatic plant native to China with Chinese name Mancao or Honduhui. The name of Mancao was first recorded in the "Classic of Mountains and Rivers" and the earliest documented medicinal function of this plant ...
The protective effects of metoprolol on rat myocardium at 3 400 m
XIE Hua, WANG Yanling, WANG Chang, LI Wenbin, JIA Zhengping, WANG Rong
2018, 36(3): 238-242. doi: 10.3969/j.issn.1006-0111.2018.03.010
Abstract(3135) PDF (443KB)(375)
Abstract:
Objective To investigate the effects on myocardial mitochondria-related indexes in rats after rapid elevation to 3 400 m altitude and myocardial protection effects with metoprolol. Methods Male Wistar rats were randomly divided into three groups w...
Effects of the active constituents from Saussurea involucrata on metabolism of mice at simulated high altitude
MA Huiping, WU Ningzi, WANG Xin, JING Linlin, JIA Zhengping, ZHANG Jun
2018, 36(3): 243-246. doi: 10.3969/j.issn.1006-0111.2018.03.011
Abstract(3111) PDF (427KB)(431)
Abstract:
Objective To investigate the anti-hypoxia effects of octacosane and the petroleum ether extract from Saussurea Involucrate (PESI) on the water, sugar, lipid and protein metabolism of mice at simulated high altitude. Methods The healthy adult male ...
Pharmacodynamics of the effective anti-hypoxia constituents in Saussurea involucrata
MA Huiping, WANG Xin, WU Ningzi, JING Linlin, JIA Zhengping, ZHANG Jun
2018, 36(3): 247-249,254. doi: 10.3969/j.issn.1006-0111.2018.03.012
Abstract(3689) PDF (430KB)(471)
Abstract:
Objective To study pharmacodynamics of the effective anti-hypoxia components in the petroleum ether extract of Saussurea Involucrate (PESI) and octacosane. Methods PESI and octacosane were first evaluated by normobaric hypoxia model, acute decompr...
Study on myocardium and brain damage in rats by simulating high altitude
WU Ningzi, MA HuiPing, WANG Xin, HE Lei, JING Linlin, JIA ZhengPing
2018, 36(3): 250-254. doi: 10.3969/j.issn.1006-0111.2018.03.013
Abstract:
Objective To investigate the effect of hypoxia with cold on the heart and brain damage in rats by simulating 6 000 m high altitude at different exposure time, established a rat model of acute mountain sickness for the related mechanism studies. Met...
Anti-hypoxia activity and its protective effects of Lishukang capsule on rat brain tissue at simulated high altitude hypoxia
MA Huiping, ZHANG Jun, JIA Zhengping, MENG Panpan, JING Linlin, WANG Rong
2018, 36(3): 255-259. doi: 10.3969/j.issn.1006-0111.2018.03.014
Abstract:
Objective To investigate anti-hypoxia activity and protective effects of Lishukang capsule on rat brain tissue at simulated high altitude hypoxia. Methods The anti-hypoxic activity of Lishukang capsule was evaluated with normobaric hypoxia test an...
The efficacy and safety evaluation of donepezil combined with memantine for the treatment of Alzheimer's disease
WAN Suxin, XIANG Yi, LUO Yaling
2018, 36(3): 260-264,281. doi: 10.3969/j.issn.1006-0111.2018.03.015
Abstract:
Objective To evaluate the efficacy and safety of donepezil combined with memantine in the treatment of Alzheimer's disease and provide a guidance for the proper clinical use of those medications. Methods The literatures published from 2014 to 2016...
Establishment of quality standards for Xiangsu Weitong Capsule
ZHAO Xin, SHAO Wei, ZHANG Peng, XU Zhiwei
2018, 36(3): 265-269,288. doi: 10.3969/j.issn.1006-0111.2018.03.016
Abstract:
Objective To establish the quality standard for Xiangsu Weitong capsule. Methods Radixet rhizoma glycyrrhizae,rhizoma corydalis,poria,rhizoma cyperi were identified by TLC and the contents of baicalin were determined by RP-HPLC. Chromatography con...
Study on hydrophilic chemical constituents from Thesium Chinensis Turcz
XUAN Weidong, FAN Zhengping, HU Shuigen, XU Dedong
2018, 36(3): 270-273. doi: 10.3969/j.issn.1006-0111.2018.03.017
Abstract(3060) PDF (261KB)(413)
Abstract:
Objective To investigate the hydrophilic chemical constituents from Thesium Chinensis Turcz. Methods The water extract of Thesium Chinensis Turcz. was adsorbed onto AB-8 resin column and eluted with 50% ethanol to give the hydrophilic portion TT50...
Determination of rutaecarpine in Fuzhengpingxiao capsule by HPLC method
LI Shengjian, QIAN Xian, ZHOU Jin, LÜ Lei, ZHANG Guoqing, ZHAO Liang
2018, 36(3): 274-276. doi: 10.3969/j.issn.1006-0111.2018.03.018
Abstract(3024) PDF (701KB)(516)
Abstract:
Objective To develop a new method to determine the contents of rutaecarpine in Fuzhengpingxiao capsule by HPLC method. Methods Samples were handled by ethanol and extraction with ethyl acetate. The separation was achieved on an Agilent TC-C18 colu...
Research of sunscreen lipstick to protect UVA and UVB
CHEN Xiao, CHEN Wenyuan, MA Peipei, QIU Haiying, DU Lina
2018, 36(3): 277-281. doi: 10.3969/j.issn.1006-0111.2018.03.019
Abstract(3721) PDF (983KB)(424)
Abstract:
Objective To prepare the sunscreen lipstick in order to prevent UVA and UVB. Methods The ratio of beeswax, castor oil and liquid paraffin were optimized with the orthogonal test based on viscosity and heat resistance. The spreadable ability, stabi...
A case study of nutritional support for a patient with malignant obstructive jaundice during the perioperative period
ZENG Yulan, SONG Hongtao
2018, 36(3): 282-284. doi: 10.3969/j.issn.1006-0111.2018.03.020
Abstract(3371) PDF (374KB)(419)
Abstract:
Objective To demonstrate the role of clinical pharmacists in nutritional support for a patient with malignant obstructive jaundice and to provide a reference for the clinical application of nutritional supplements in patients during the perioperativ...
Treatment analysis and pharmaceutical care for one infant with purulent meningitis and renal insufficiency
YING Yin, XIA Zhongni, ZHU Jun, ZOU Jie
2018, 36(3): 285-288. doi: 10.3969/j.issn.1006-0111.2018.03.021
Abstract(4081) PDF (381KB)(397)
Abstract:
Objective To discuss how the clinical pharmacists participated in the treatment of pediatric purulent meningitis and conducted drug monitoring. Methods Clinical pharmacists involved the whole process of treatment for a purulent meningitis infant w...