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2010 Vol. 28, No. 2

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2010, 28(2): 81-83,93.
Abstract(2206) PDF (602KB)(928)
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2010, 28(2): 84-87,104.
Abstract(2175) PDF (434KB)(1544)
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2010, 28(2): 88-93.
Abstract(2559) PDF (889KB)(1082)
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application of cyclodextrin and its derivatives in chiral separation and analysis
ZHU Fang
2010, 28(2): 94-96,111.
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About half of the drugs in use are chiral,however,that in most cases the pharmacological activity is restricted to one of the enantiomers(eutomer) whereas the other enantiomer(distomer) can be even toxic.The development of Methods for enantioselectiv...
2010, 28(2): 97-100,136.
Abstract(3004) PDF (973KB)(1784)
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Antibiotic tests of different polar extracts of Artemisia anomala in vitro
TAN Wei-feng, WANG Jingb, XING Xinb, QING Lu-pingc
2010, 28(2): 101-104.
Abstract(3081) PDF (305KB)(785)
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Objective The antibiotic tests of different polar extracts of Artemisia anomala S.Moore in vitro. Methods The antibiotic tests of different polar extracts of AASM in vitro were performed by using Kirby-Bauer method and broth dilution method. Result...
Anticancer and phytochemical properties of alkaloids from Caragana microphylla
ZHANG Guo-qing, WANG Ke-bing
2010, 28(2): 105-106,121.
Abstract(2851) PDF (202KB)(550)
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Objective To identify the composition of the total alkaloids of the seeds of Caragana microphylla,a native plant from the North west of China which is used in traditional Mongolian medicines. Methods The alkaloids was separated and identified by ch...
Study on inhibition of mimic peptides binding specifically with the first and second extra-cellular domain of CC chemokine receptor 5 on mice ear engorgement induced by dimethyl benzene
ZHENG Hui-min, GUO Bao-yu1
2010, 28(2): 107-111.
Abstract(2333) PDF (582KB)(412)
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Objective To study the inhibition of mimic peptides binding specifically with the first and second extra-cellular domain of the CC chemokine receptor 5(CCR5) on mice ear engorgement induced by dimethyl benzene. Methods Phage display peptide library...
Effects of tentacle-only extract from jellyfish Cyanea capillata on the conduction system of isolated rat heart
CAI Bin-xin, GUO Yu-feng, ZHANG Zhi, XIAO Liang, ZHANG Li-ming
2010, 28(2): 112-113,125.
Abstract(2806) PDF (513KB)(653)
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Objective To observe the effects of tentacle-only extract(TOE) from Cyanea capillata on the conduction system of isolated rat heart and investigate the mechanism of its cardiac toxicity. Methods Seventy-two Sprague Dawley(SD) rats were randomly div...
Enzymatic extraction and antibacterial activity of total flavonoids from Sedum sarmentosum
GONG Yan-ling, HUANG Shan, YU Hui-rong
2010, 28(2): 114-115,153.
Abstract(2412) PDF (604KB)(579)
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Objective To investigate the technology of total flavonoids in Sedum sarmentosum extracted by enzymatic method and its antibacterial activity. Methods Total flavonoids in Sedum sarmentosum was extracted by the method that enzymatic hydrolysis combi...
Optimization of extraction technology for Sanhuang Jiedu cream by orthogonal test
LIU Jun, DU Jian-ping, SHI Zhi-qi
2010, 28(2): 116-117,133.
Abstract(2789) PDF (174KB)(360)
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Objective To optimize the extraction technology for Sanhuang Jiedu cream. Methods The optimum extraction technology for Sanhuang Jiedu cream was investigated by the L9(34) orthogonal test with the total amount of the dry extract and the content of ...
Studies of preparation and in vitro Absorption of ginkgo biloba leaf in-situ nasal gel
CUI Hai-zhen, LIU Fu-qiang, WANG Yan-ping, ZHAO Nan, LI Zi-yan
2010, 28(2): 118-121.
Abstract(2213) PDF (406KB)(654)
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Objective To preparation of ginkgo biloba leaf in-situ nasal gel and exploration of the effect of sorbefacients on nasal mucosa Absorption. Methods Carbopol 934 and HPMC were used as gel matrix to prepare pH sensitive in-situ ginkgo biloba leaf nas...
Preparation and in vitro release of pH-triggered levofloxacin hydrochloride in-situ forming gel for sustained ophthalmic delivery
ZHANG Zhi-qiang, ZHANG Wei, CHEN guang, ZHANG Minga, HUO Jun-bina, CUI Lei, CHU Hao-wen, Gao Jing
2010, 28(2): 122-125.
Abstract(3053) PDF (924KB)(596)
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Objective To develop the pH-triggered levofloxacin hydrochloride in-situ forming eye gel. Methods The gel was formed carpool as gel base and hydroxypropyl methylcellulose(HPMC) as thickening agents,and was the foluma evaluated according to the visc...
Preparation of sirolimus sustained-release tables and observe of influence factors on releasing drug
ZHANG Jing, WANG Juan, SONG Hong-tao, TANG Xing, HE Zhong-gui
2010, 28(2): 126-129,139.
Abstract:
Objective To prepare the sirolimus sustained-release tablets and study the influence factor. Methods The sirolimus sustained-release tablets were prepared by HPMC as the matrix material.The effects of viscosity of HPMC,sort of an adhensive amount o...
Research strategy of chiral separation by capillary electrophoresis
CHEN Wei-cheng, LIU Chang-hai, ZHANG Hai, ZHU Zhen-yu, ZHAO Liang, ZHANG Guo-qing, CHAI Yi-feng
2010, 28(2): 130-133.
Abstract(2387) PDF (645KB)(401)
Abstract:
The selection method of separation condition and cyclodextrin and strategy of chiral separation by capillary electrophoresis were summarized,and a general research and development strategy was proposed,which can provide basis for chiral separation by...
Determination of auantion and uracil in Eupolyphaga seu Steleophaga by HPLC
JING Jing, CAO Hong
2010, 28(2): 134-136.
Abstract(2645) PDF (593KB)(1140)
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Objective To establish a method for determination of uracil and auantion in Eupolyphaga seu Steleophaga by HPLC. Methods The HPLC separation was performed on Alltima NH2(150 mm×4.6 mm,5 μm)column with a mixture of acetonitrile-water(9010)as the mo...
Determination of polygalasaponin F in Polygala japonica by HPLC-ELSD method
JIAO Qing-qing, WANG Wei-yun, SU Juan, ZHANG Wei-dong
2010, 28(2): 137-139.
Abstract(2478) PDF (588KB)(734)
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Objective To establish an effective quality control method of the traditional Chinese medicine——Polygala japonica Houtt. Methods HPLC-ELSD method was adopted for the determination of polygalasaponin F in Polygala japonica Houtt.The analysis was per...
Practice and experience of prescription evaluation program in the hospital in recent two years
ZHANG Xian-li, HUO Hua, ZAI Li
2010, 28(2): 140-142.
Abstract(2356) PDF (614KB)(513)
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Objective To conclude the Practice and experience of prescription evaluation program. Methods To take a sample of 120 prescriptions every month during July 2007 to July 2009,calculate the average of each indicator of the prescription evaluation tab...
2010, 28(2): 142-145.
Abstract(2191) PDF (300KB)(591)
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Clinical utilization research of total parenteral nutrition(TPN)
CAI Shen, ZHENG Ying-li, FANG Li, WANG Ying
2010, 28(2): 145-147.
Abstract(2580) PDF (661KB)(758)
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Objective To investigate the utilization of TPN so as to provide some references for rational use in the clinic. Methods 145 cases treated with TPN were reviewed retrospectively and the medication indications and drug consumption were analyzed stat...
2010, 28(2): 148-149.
Abstract(1969) PDF (340KB)(1196)
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2010, 28(2): 150-152.
Abstract(1973) PDF (595KB)(252)
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2010, 28(2): 153-153.
Abstract(1846) PDF (78KB)(366)
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2010, 28(2): 154-155.
Abstract(1936) PDF (115KB)(333)
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2010, 28(2): 156-160.
Abstract(1938) PDF (662KB)(215)
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