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慢性乙型肝炎的抗病毒研究进展

操跃,  钱其军

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文章导航 > 药学实践与服务  > 2015 >  33(6): 561-565
操跃, 钱其军. 慢性乙型肝炎的抗病毒研究进展[J]. 药学实践与服务, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
引用本文: 操跃, 钱其军. 慢性乙型肝炎的抗病毒研究进展[J]. 药学实践与服务, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
shu
CAO Yue, QIAN Qijun. Progress in study of antiviral effect of chronic hepatitis B[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
Citation: CAO Yue, QIAN Qijun. Progress in study of antiviral effect of chronic hepatitis B[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
shu

慢性乙型肝炎的抗病毒研究进展

doi: 10.3969/j.issn.1006-0111.2015.06.022
  • 1.

    福建医科大学第一临床医学院, 福建 福州 350108;第二军医大学附属东方肝胆外科医院肿瘤生物治疗科、病毒基因治疗实验室, 上海 200438

  • 2.

    第二军医大学附属东方肝胆外科医院肿瘤生物治疗科、病毒基因治疗实验室, 上海 200438

Progress in study of antiviral effect of chronic hepatitis B

  • 1.

    First Clinical Medical College, Fujian Medical University, Fuzhou 350108, China;Laboratory of Gene and Viral Therapy, Department of Biotherapy, Eastern Hepatobiliary Surgery Hospital Affiliated to Second Military Medical University, Shanghai 200438, China

  • 2.

    Laboratory of Gene and Viral Therapy, Department of Biotherapy, Eastern Hepatobiliary Surgery Hospital Affiliated to Second Military Medical University, Shanghai 200438, China

  • 摘要: 慢性乙型肝炎是由乙型肝炎病毒(hepatitis B virus,HBV)引起的全球性传染病,HBV感染是我国肝硬化、原发性肝癌的重要原因。目前,干扰素类与核苷(酸)类似物抗病毒药物已广泛应用于临床,在一定程度上抑制了病毒的复制并控制了疾病的发展,但仍未从根本上清除病毒;各种治疗性疫苗在抗HBV方面也取得了一定疗效,但临床效果不佳。目前不少研究结果表明,生物免疫治疗可以成功清除体内的HBV,从而为乙肝的治疗带来新的希望。
    Abstract: Chronic hepatitis B is a worldwide infectious diseases caused by hepatitis B virus (HBV). HBV infection is an important reason for liver cirrhosis and liver cancer in our country. Currently, the interferon and nucleoside analogs antiviral drugs (nucleotides) is widely used in clinical practice. These drugs inhibit the replication of the virus and disease development to a certain extent, but not fundamentally eliminate the virus. Various therapeutic vaccines have also made certain curative effect in anti HBV, but the effect is not perfect clinically. At present, many research Results demonstrate that biological immunotherapy can successfully eliminate HBV virus in the body, therefore it has brought a new hope for the treatment of hepatitis B.
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慢性乙型肝炎的抗病毒研究进展

doi: 10.3969/j.issn.1006-0111.2015.06.022
  • 1. 福建医科大学第一临床医学院, 福建 福州 350108;第二军医大学附属东方肝胆外科医院肿瘤生物治疗科、病毒基因治疗实验室, 上海 200438
  • 2. 第二军医大学附属东方肝胆外科医院肿瘤生物治疗科、病毒基因治疗实验室, 上海 200438
  • 收稿日期: 2015-02-10
  • 修回日期: 2015-07-13

摘要: 慢性乙型肝炎是由乙型肝炎病毒(hepatitis B virus,HBV)引起的全球性传染病,HBV感染是我国肝硬化、原发性肝癌的重要原因。目前,干扰素类与核苷(酸)类似物抗病毒药物已广泛应用于临床,在一定程度上抑制了病毒的复制并控制了疾病的发展,但仍未从根本上清除病毒;各种治疗性疫苗在抗HBV方面也取得了一定疗效,但临床效果不佳。目前不少研究结果表明,生物免疫治疗可以成功清除体内的HBV,从而为乙肝的治疗带来新的希望。

English Abstract

操跃, 钱其军. 慢性乙型肝炎的抗病毒研究进展[J]. 药学实践与服务, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
引用本文: 操跃, 钱其军. 慢性乙型肝炎的抗病毒研究进展[J]. 药学实践与服务, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
shu
CAO Yue, QIAN Qijun. Progress in study of antiviral effect of chronic hepatitis B[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
Citation: CAO Yue, QIAN Qijun. Progress in study of antiviral effect of chronic hepatitis B[J]. Journal of Pharmaceutical Practice and Service, 2015, 33(6): 561-565. doi: 10.3969/j.issn.1006-0111.2015.06.022
shu

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