摘要:
目的:评价五水头孢唑林钠治疗急性期慢性阻塞性肺炎（COPD）的疗效与安全性。方法:用随机对照试验设计,随机分为3组:五水头孢唑林钠组25例,头孢唑林钠组21例,头孢他啶组19例,3组的用法、用量、疗程相同,每日2次,每次静滴2 g,疗程7～14 d。结果:疗程结束时,五水头孢唑林钠与头孢唑林钠、头孢他啶痊愈率和有效率分别为80.00%,71.43%,47.37%和92.00%,85.71%,63.16%;药物不良反应发生率分别为4.00%,4.76%,5.26%。结论:五水头孢唑林钠治疗慢性阻塞性肺炎,疗效确切,安全性较好。
Abstract:
Objective :To evaluate the efficacy and safety of cefazolin sodium pentahydrate in the treatment of acute stage of COPD. Methods : A randomized,controlled clinical trail was carried.A total of 65 patients of COPD were randomly divided into three groups(trial:25 cases,controlⅠ21 cases,controlⅡ19 cases),were administered intravenously at a dose of 2 g,bid,for 7 to 14 days. Results :At the end of the treatment,the cure rate and effective rate of three group were 80.00%(trial),71.43%(controlⅠ),47.37%(controlⅡ) amd 92.00%(trial),85.71%(controlⅠ),63.16%(controlⅡ) respectively.The incidence of adverse drug reaction were 4.00%,4.76%,5.26% respectively. Conclusion : The cefazolin sodium pentahydrate had an excellent clinical efficacy and good safety in treating patients with CODP.
点击查看大图
下载:
