美洛西林钠在木糖醇输液中的配伍稳定性考察
Study on the stability of compatibility of mezlocillin sodium in 5% xylitol injection
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摘要: 目的: 考察不同温度(25℃、37℃)下6h内,美洛西林钠与木糖醇的配伍稳定性。 方法: 用紫外分光光度法测定配伍液中关洛西林含量,并观察外观、pH值的变化。 结果: 美洛西林钠与木糖醇输液配伍后6 h内,其外观,pH值以及含量均无明显变化。 结论: 美洛西林在上述条件下可以与木糖醇输液配伍使用。Abstract: Objective:To study the stability of compatibility of mezlocillin sodium in 5% xylitol injection at different temperature (25℃、37℃)winthin six hours.Methods :The content of mezlocillin was determined by UV-spectrophotometry,and the appearance of the solution was observed and its pH value was tested. Results: There were no significant changes in appearance,pH value and con- tent of the mixed solution winthin six hours. Conclusion: Mezlocillin sodium mixed with 5% xylitol injection can be used under above- mentioned conditions winthin six hours
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Key words:
- mezlocillin sodium /
- xylitol injection /
- compatibility /
- stability /
- UV-spectrophometry
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