黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察

柯晓; 周宗梅; 文明; 文彩云

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

x 关闭永久关闭

重要提示

《药学实践与服务》杂志不接收生物战剂、毒剂相关内容的稿件。对于涉军信息类论文如需投稿，请务必投稿前电话或邮箱咨询。联系电话：021-81871323，邮箱：yxsjzzs@163.com。敬请谅解，谢谢配合！

《药学实践与服务》编辑部

重要通知

《药学实践与服务》杂志目前不收取审稿费、版面费、加急费等费用，如收到邮件声称是编辑部X编辑，要求加作者微信的，或填写编委登记申请表的，请谨防诈骗！

编辑部用于作者校稿时微信绑定的邮件是通过官方邮箱：yxsjzzs@163.com发送的，标题是《药学实践与服务》XML数字出版服务微信绑定，请区分开！如有疑虑，请联系编辑部，电话：021-81871323。

《药学实践与服务》编辑部

黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察

柯晓, 周宗梅, 文明, 文彩云

文章导航 > 药学实践与服务 > 2004 > (5): 268-270

柯晓, 周宗梅, 文明, 文彩云. 黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察[J]. 药学实践与服务, 2004, (5): 268-270.

引用本文:

柯晓, 周宗梅, 文明, 文彩云. 黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察[J]. 药学实践与服务, 2004, (5): 268-270.

KE Xiao, ZHOU Zong-mei, WEN Min, WEN Cai-yun. Effect of astragalus membranaceus injection on congestive heart failure and im- mune regulation[J]. Journal of Pharmaceutical Practice and Service, 2004, (5): 268-270.

Citation:

KE Xiao, ZHOU Zong-mei, WEN Min, WEN Cai-yun. Effect of astragalus membranaceus injection on congestive heart failure and im- mune regulation[J]. Journal of Pharmaceutical Practice and Service, 2004, (5): 268-270.

黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察

湖北省荆州市第三人民医院, 湖北荆州 434001

Effect of astragalus membranaceus injection on congestive heart failure and im- mune regulation

The Third People Hospital of Jingzhou City, Jingzhou 434001, China

摘要: 目的探讨黄芪注射液对充血性心力衰竭(CHF)患者的疗效及对免疫调节的影响。方法对正常体检查者(体检组)和CHF组进行IgA、IgG、IgM、C3、IL-Ⅱ、E-RFC、T-LTT、抗心肌抗体的检查;然后将CHF组患者随机分为两组,治疗组在应用转换酶抑制剂、利尿剂和强心苷等常规治疗的基础上加用黄芪注射液60mL+10%葡萄糖注射液500mL静脉滴注,每日1次,连用2周,对照组仅给予常规治疗;2周后重复上述检查,进行体检组与CHF和治疗组与对照组的对比分析。结果体检组与CHF组比较,IL-Ⅱ、E-RFC、T-LTT、C3和抗心肌抗体CHF组明显高于体检组(P<0.05);治疗2周后,两组比较心衰治疗的总有效率无明显差异(P>0.05),但显效率治疗组明显优于对照组(P<0.05);治疗组IL-Ⅱ、E-RFC、T-LTT、C3和抗心肌抗体的改变明显优于对照组(P<0.01)。结论黄芪注射液对心衰的疗效很大程度上是通过对细胞免疫作用实现的,其辅助治疗可获满意的疗效。
- 心力衰竭 /
- 充血性 /
- 免疫 /
- 黄芪注射液
Abstract: Objective To explore the effect of Astragalus membranaceus injection on congestive heart failure and immune regulation. Methods The serum levers of IgA IgG IgM C3 IL-Ⅱ E-RFC T-LTT and antibody of cardiac muscle were measured in normal control group and CHF group. Then the CHF patients were divided randomly into two groups. Treatment group was infused intravenously daily with Astragalus membranaceus injection added into 5% glucose 250mL for two weeks, which was based on conventional therapy such as digitalis, diuretics and vasodilators. Conventional therapy group was only treated with conventional thearpy. Previous measurements were done again after two weeks. Comparative analysis was made between normal control group and CHF group, and also was made between conventional therapy group and treatment group. Results The level of IL-Ⅱ E-RFC T-LTT antibody of cardiac muscle in the CHF paients were significantly higher then that of normal control group (P<0.01). After two weeks, there was no significant difference in the total effective rate of CHF between two groups (P>0.05), but the obvious effective rate of treatment group was markedly higher than that of conventional therapy group(P >0.05). The decrease of IL-Ⅱ E-RFC T-LTT C3 and antibody of cardiac muscle in treatment group is more obvious than that in conventional therapy group (P<0.01). Conclusion The effect of Astragalus membranaceus injection on cogestive heart failure involves mainly the cell immune and Astragalus membranaceus may have a satisfied cure effect on it.
- Astragalus membranaceus /
- heart failure /
- congestive /
- immunity

[1]	张婷婷, 黄晶晶, 梁静蕾, 庞涛, 陈万生, 张凤. 基于超高效液相质谱联用技术分析不同产地桔梗皂苷类成分的差异 . 药学实践与服务, 2026, 44(4): 189-199, 208. doi: 10.12206/j.issn.2097-2024.202506026
[2]	黄欣, 杨茹洁, 秦峰, 张士莲, 吴莘, 尹小燕. 硫酸镁钠钾口服液在内镜肠道清洁准备中的效果 . 药学实践与服务, 2026, 44(2): 85-87, 102. doi: 10.12206/j.issn.2097-2024.202311049
[3]	李霞, 孙悦, 付晓菲. 临床药师参与注射用哌拉西林钠他唑巴坦钠致极重度血小板增多的病例分析 . 药学实践与服务, 2026, 44(5): 1-4. doi: 10.12206/j.issn.2097-2024.202601008
[4]	刘志丽, 吴相雷, 胡云英, 王慧, 鲍蕾蕾. 22例免疫检查点抑制剂致免疫相关性肺炎病例分析 . 药学实践与服务, 2026, 44(): 1-4. doi: 10.12206/j.issn.2097-2024.202512023
[5]	赵雪, 顾妍秋, 楚皓文, 吴彩胜, 李镐, 陈啸飞. 基于超高效液相色谱-四极杆飞行时间质谱的麻杏石甘汤化学成分分析 . 药学实践与服务, 2025, 43(11): 548-554, 571. doi: 10.12206/j.issn.2097-2024.202306028
[6]	舒飞, 孙蕊, 宋凯, 张元林, 闫家铭, 舒丽芯. 粉-液双室袋产品的综合评价 . 药学实践与服务, 2025, 43(2): 92-96. doi: 10.12206/j.issn.2097-2024.202312009
[7]	张俊丽, 李媛媛, 尹静, 杨鸿源, 白耀武. 咪达唑仑调节PINK1/PARKIN信号通路对缺血性脑卒中大鼠神经元损伤的影响 . 药学实践与服务, 2025, 43(6): 288-292, 312. doi: 10.12206/j.issn.2097-2024.202405024
[8]	刘祉君, 崔莉莉, 许封菁, 宋新华, 王志鹏, 高守红. 胆汁酸和胆汁酸受体的免疫调节作用及其在结直肠癌发生发展中的研究进展 . 药学实践与服务, 2025, 43(12): 583-590. doi: 10.12206/j.issn.2097-2024.202312024
[9]	王鹏, 张争艳, 吴宗贵. 活心丸（浓缩丸）联合八段锦对急性心肌梗死合并心力衰竭介入术预后的影响 . 药学实践与服务, 2025, 43(7): 348-352. doi: 10.12206/j.issn.2097-2024.202308034
[10]	石晓萍, 吕迁洲, 李晓宇, 许青. 泊沙康唑对比伏立康唑经验治疗或诊断驱动治疗免疫功能低下患者侵袭性霉菌病的成本-效果分析 . 药学实践与服务, 2024, 42(12): 512-519. doi: 10.12206/j.issn.2097-2024.202401050
[11]	唐淑慧, 凤美娟, 薛智霞, 鲁桂华. 帕博利珠单抗治疗所致免疫相关不良反应与中医体质的相关性研究 . 药学实践与服务, 2024, 42(5): 217-222. doi: 10.12206/j.issn.2097-2024.202311029
[12]	顾佳钰, 胡馨儿, 王晓飞, 张颖, 张海, 曹岩. 侧流免疫层析定量检测方法的研究进展 . 药学实践与服务, 2024, 42(7): 273-277, 284. doi: 10.12206/j.issn.2097-2024.202307037
[13]	马兹芬, 许维恒, 金煜翔, 薛磊. 食管癌的靶向治疗与免疫治疗研究进展 . 药学实践与服务, 2024, 42(6): 231-237. doi: 10.12206/j.issn.2097-2024.202306008
[14]	景凯, 杨慈荣, 张圳, 臧艺蓓, 刘霞. 黄芪甲苷衍生物治疗慢性心力衰竭小鼠的药效评价及作用机制研究 . 药学实践与服务, 2024, 42(5): 190-197. doi: 10.12206/j.issn.2097-2024.202310004

点击查看大图

计量

文章访问数: 3290
HTML全文浏览量: 267
PDF下载量: 806
被引次数: 0

黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察

湖北省荆州市第三人民医院, 湖北荆州 434001

收稿日期: 2004-04-08

关键词:

心力衰竭 /

充血性 /

免疫 /

黄芪注射液

摘要: 目的探讨黄芪注射液对充血性心力衰竭(CHF)患者的疗效及对免疫调节的影响。方法对正常体检查者(体检组)和CHF组进行IgA、IgG、IgM、C3、IL-Ⅱ、E-RFC、T-LTT、抗心肌抗体的检查;然后将CHF组患者随机分为两组,治疗组在应用转换酶抑制剂、利尿剂和强心苷等常规治疗的基础上加用黄芪注射液60mL+10%葡萄糖注射液500mL静脉滴注,每日1次,连用2周,对照组仅给予常规治疗;2周后重复上述检查,进行体检组与CHF和治疗组与对照组的对比分析。结果体检组与CHF组比较,IL-Ⅱ、E-RFC、T-LTT、C3和抗心肌抗体CHF组明显高于体检组(P<0.05);治疗2周后,两组比较心衰治疗的总有效率无明显差异(P>0.05),但显效率治疗组明显优于对照组(P<0.05);治疗组IL-Ⅱ、E-RFC、T-LTT、C3和抗心肌抗体的改变明显优于对照组(P<0.01)。结论黄芪注射液对心衰的疗效很大程度上是通过对细胞免疫作用实现的,其辅助治疗可获满意的疗效。

English Abstract

Effect of astragalus membranaceus injection on congestive heart failure and im- mune regulation

The Third People Hospital of Jingzhou City, Jingzhou 434001, China

Received Date: 2004-04-08

Keywords:

Abstract: Objective To explore the effect of Astragalus membranaceus injection on congestive heart failure and immune regulation. Methods The serum levers of IgA IgG IgM C3 IL-Ⅱ E-RFC T-LTT and antibody of cardiac muscle were measured in normal control group and CHF group. Then the CHF patients were divided randomly into two groups. Treatment group was infused intravenously daily with Astragalus membranaceus injection added into 5% glucose 250mL for two weeks, which was based on conventional therapy such as digitalis, diuretics and vasodilators. Conventional therapy group was only treated with conventional thearpy. Previous measurements were done again after two weeks. Comparative analysis was made between normal control group and CHF group, and also was made between conventional therapy group and treatment group. Results The level of IL-Ⅱ E-RFC T-LTT antibody of cardiac muscle in the CHF paients were significantly higher then that of normal control group (P<0.01). After two weeks, there was no significant difference in the total effective rate of CHF between two groups (P>0.05), but the obvious effective rate of treatment group was markedly higher than that of conventional therapy group(P >0.05). The decrease of IL-Ⅱ E-RFC T-LTT C3 and antibody of cardiac muscle in treatment group is more obvious than that in conventional therapy group (P<0.01). Conclusion The effect of Astragalus membranaceus injection on cogestive heart failure involves mainly the cell immune and Astragalus membranaceus may have a satisfied cure effect on it.

柯晓, 周宗梅, 文明, 文彩云. 黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察[J]. 药学实践与服务, 2004, (5): 268-270.

引用本文:

柯晓, 周宗梅, 文明, 文彩云. 黄芪注射液辅助治疗充血性心力衰竭的疗效及对免疫调节影响的观察[J]. 药学实践与服务, 2004, (5): 268-270.

Citation: