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2022 Vol. 40, No. 3

Cover Catalogue
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Advances in methodologies for preparation and analysis of new biochromatic stationary phase
CHAI Xinyi, GU Yanqiu, CHEN Xiaofei, CHAI Yifeng
2022, 40(3): 193-198. doi: 10.12206/j.issn.1006-0111.202112087
Abstract(7444) HTML (3157) PDF (1325KB)(70)
Abstract:
Biochromatography is a new chromatographic technology with great development potential. It has been widely used in drug screening and biomolecular interaction analysis. The core of this technology is the chromatographic stationary phase of biomolecul...
Advances in prevention and treatment for motion sickness
ZHANG Jingxiang, ZHU Lin, XING Xinhao, WANG Xinrong, WANG Yan
2022, 40(3): 199-201, 247. doi: 10.12206/j.issn.1006-0111.202101018
Abstract(8510) HTML (4061) PDF (1226KB)(314)
Abstract:
Motion sickness is a series of physiological responses in human being caused by abnormal movement stimulation. With the development of science and technology, a growing number of people choose to travel by high speed vehicles. Motion sickness happens...
Overview of surface-enhanced Raman spectroscopy in combination with other detection techniques
CUI Xiaolin, GUI Ling, ZHU Qian, LU Feng
2022, 40(3): 202-207, 253. doi: 10.12206/j.issn.1006-0111.202110091
Abstract(9066) HTML (9048) PDF (1597KB)(113)
Abstract:
As an increasingly mature analytical technique, surface-enhanced Raman spectroscopy has the ability to identify, detect, and even quantitatively measure many single substances in nature. However, in the actual sample analysis, the tested samples were...
Research progress of STAT3 on liver disease
LI Tingting, ZHANG Junping
2022, 40(3): 208-212, 280. doi: 10.12206/j.issn.1006-0111.202109072
Abstract(7393) HTML (3026) PDF (1274KB)(60)
Abstract:
Signal transduction and transcriptional activator 3 (STAT3) is an important transcription factor that can be activated by many cytokines and growth factors. STAT3 plays a key role in cell growth, proliferation, and differentiation. It has been shown ...
Effects of endophytic fungus SH09 on plant growth and accumulation of active components in Salvia miltiorrhiza
WU Sijia, XIE Xingguang, YANG Yang, ZHENG Chengjian, HAN Ting
2022, 40(3): 213-217, 269. doi: 10.12206/j.issn.1006-0111.202108055
Abstract(5179) HTML (1752) PDF (1810KB)(35)
Abstract:
Objective  To study the effects of endophytic fungus Epichloë bromicola SH09 on the plant growth and accumulation of active components in Salvia miltiorrhiza, and improve the quality of medicinal plant S. miltiorrhiza.   Methods  E. bromicola SH09...
Characterization and function of short-chain dehydrogenases/reductases in hydroxysafflower yellow A biosynthesis pathway
WANG Lunuan, WU Jianhui, HE Beixuan, ZHANG Yanjie, GUO Meili
2022, 40(3): 218-225. doi: 10.12206/j.issn.1006-0111.202201061
Abstract(7025) HTML (2462) PDF (2462KB)(57)
Abstract:
Objective  To explore the function of short-chain dehydrogenases/reductases (SDRs) in safflower flavonoid, especially hydroxysafflower yellow A (HSYA) biosynthesis.   Methods  SDRs involved in HSYA biosynthesis pathway were screened based on saffl...
Long-term protective effects of the nicotiflorin on ischemic stroke rats
YAN Xiaodong, WANG Yeqing, LI Bingfeng, GUO Meili
2022, 40(3): 226-230, 258. doi: 10.12206/j.issn.1006-0111.202201080
Abstract(5049) HTML (1844) PDF (1620KB)(33)
Abstract:
Objective  To investigate the long-term protective effects of the nicotiflorin on ischemic stroke rats.   Methods   Ischemic stroke model in rats was established for this study. The effects of nicotiflorin on long-term survival rate, nervous syste...
Analysis of chemical ingredients of modified Shenqi Dihuang decoction by UPLC-LTQ-Orbitrap-MS
WAN Zhong, LIU Wangzhenzu, TAN Mingyue, XU Dongliang, HU Cheng, JI Wanli
2022, 40(3): 231-237, 264. doi: 10.12206/j.issn.1006-0111.202112054
Abstract(4517) HTML (2916) PDF (1726KB)(24) Cited By (4)
Abstract:
Objective  To analyze the chemical compounds of Shenqi Dihuang decoction by the ultraperformance liquid chromatography coupled with linear quadrupole ion trap-orbitrap mass spectrometry (UPLC-LTQ-Orbitrap-MS).   Methods  Warters ACQUITY UPLC HSS T...
Safety pharmacological study of the compound of diphenhydramine hydrochloride and caffeine
REN Lijun, GU Jing, SHI Wenjing, WANG Ruina, ZHANG Xiaofang, CHEN Jikuai
2022, 40(3): 238-242, 285. doi: 10.12206/j.issn.1006-0111.202105115
Abstract(3934) HTML (1890) PDF (1258KB)(20)
Abstract:
Objective   To provide the reference resource for the safe clinical use of the compound of diphenhydramine hydrochloride and caffeine by observing its effects on the nervous system, cardiovascular system and respiratory system in experimental animal...
Determination of total polyphenols and catechins in betel nut polyphenol extract
MA Jianghong, WANG Rong, DU Xing, ZHAO Anpeng, WANG Zihan, ZHANG Haobo
2022, 40(3): 243-247. doi: 10.12206/j.issn.1006-0111.202106013
Abstract(4509) HTML (1967) PDF (1056KB)(23)
Abstract:
Objective   To establish a method for the determination of total polyphenols and catechins in betel nut polyphenols extract, and provide reference for the quality control of betel nut polyphenols extract.   Methods   The content of total phenol in...
Hexokinase inhibitor 2-deoxyglucose combined with phenformin induces cell apoptosis of triple-negative breast cancer
YE Linlan, HE Chunhui, ZHU Xuting, LI Xia
2022, 40(3): 248-253. doi: 10.12206/j.issn.1006-0111.202103045
Abstract(5020) HTML (2063) PDF (1702KB)(13)
Abstract:
Objective   To investigate the effect of phenformin combined with hexokinase inhibitor 2-deoxyglucose (2-DG) on the treatment of triple-negative breast cancer cell lines 4T1 and MDA-MB-231.   Methods   Following treatment with phenformin, 2-DG or ...
Mechanism of Psoralea corylifolia Linn on liver injury based on bioinformatics
YU Dan, CHI Xiaowei
2022, 40(3): 254-258. doi: 10.12206/j.issn.1006-0111.202103054
Abstract(5637) HTML (2723) PDF (1269KB)(36)
Abstract:
Objective  To explore the mechanism of Psoralea corylifolia Linn (PCL) on liver injury by establishing the biological function and pathway network of PCL components, targets and protein interactions based on bioinformatics.   Methods  The componen...
Effect of traditional Chinese medicine Syngnathus on D-galactose-induced learning and memory impairment in aging mice
ZHANG Jingwen, HE Xuhui, XIA Tianshuang, JIANG Yiping, XIN Hailiang
2022, 40(3): 259-264. doi: 10.12206/j.issn.1006-0111.202201074
Abstract(5372) HTML (2640) PDF (2401KB)(18)
Abstract:
Objective  To study the effect of traditional Chinese medicine, Syngnathus on learning and memory impairment induced by D-galactose in aging mice and its mechanism of action.  Methods  HPLC was used to determine the content of DHA, the active ingr...
The standard specification of microscopic identification of Chinese Pharmacopoeia 2020 edition
LU Lun, ZHANG Chengzhong
2022, 40(3): 265-269. doi: 10.12206/j.issn.1006-0111.202103079
Abstract(6890) HTML (4618) PDF (965KB)(37)
Abstract:
Objective  To improve the standardization and legitimacy of the quality control for traditional Chinese medicine (TCM) by analyzing the microscopic identification quality standard of TCM in Chinese Pharmacopoeia 2020 edition (Volume 1).   Methods ...
Quality standard improvement study of ginkgo semen decoction pieces
TU Yan, DONG Zhiying, HUANG Mengqiu, TAN Jingfu, CHEN Weixu, SUN Lianna
2022, 40(3): 270-273. doi: 10.12206/j.issn.1006-0111.202103007
Abstract(7839) HTML (2041) PDF (948KB)(26)
Abstract:
Objective   To establish and improve the quality standard of ginkgo semen decoction pieces.   Methods   The morphological character for 29 batches of ginkgo gemen and 12 batches of stir-fried ginkgo gemen were observed, and the moisture contents w...
Diphenhydramine hydrochloride asaay in compound diphenhydramine cream by HPLC
LU Songwei, LUO Jinqian, YU Huihua, CHEN Fangjian
2022, 40(3): 274-276. doi: 10.12206/j.issn.1006-0111.202102016
Abstract(3825) HTML (1433) PDF (906KB)(33)
Abstract:
Objective  To establish the HPLC method of assay for diphenhydramine hydrochloride in compound diphenhydramine cream.   Method   HPLC analysis was carried on ACE5C18S/N-A66766 column (150 mm×4.6 mm, 5 µm) with the mobile phase of methanol-water-tr...
Interaction between cyclosporine A and voriconazole in patients with allogeneic hematopoietic stem cell transplantation
WANG Yani, WU Di, RAO Zhi, LI Maoxing, XI Rui, REN Jun
2022, 40(3): 277-280. doi: 10.12206/j.issn.1006-0111.202111056
Abstract(4522) HTML (1723) PDF (1306KB)(9)
Abstract:
Objective  To analyze the drug-drug interaction (DDI) between intravenous voriconazole (VRZ) and intravenous cyclosporine (CsA) in patients after allogeneic hematopoietic stem cell transplantation (Allo-HSCT) and provide an individualized and accura...
Study on the rules of traditional Chinese medicine to promote wound healing based on data mining
LEI Zhongwei, DU Jie, SUN Hongyi, GU Qinwufeng, LI Bai, YANG Yanlong
2022, 40(3): 281-285. doi: 10.12206/j.issn.1006-0111.202104099
Abstract(5510) HTML (2321) PDF (1059KB)(32)
Abstract:
Objective   To provide new ideas for promoting wound healing by digging and sorting out the medication rules in ancient classics and modern literatures.   Methods   The prescriptions for promoting wound healing recorded in literatures were collect...
The pharmaceutical care by clinical pharmacists for a foot injury patient with postoperative MRSA infection
LUO Jingjing, WU Xinan, XUE Gang, XIE Zhengdong, YE Jianbo, RONG Chengting
2022, 40(3): 286-288. doi: 10.12206/j.issn.1006-0111.202102004
Abstract(9894) HTML (3163) PDF (884KB)(69)
Abstract:
Objective  To explore the clinical pharmacist’s role in drug therapy and monitoring for the patient with postoperative MRSA infection.   Methods  Clinical pharmacists participated in planning anti-infective treatment, antimicrobial medication sele...