2022 Vol. 40, No. 2
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2022, 40(2): 97-102.
doi: 10.12206/j.issn.1006-0111.202111059
Abstract:
Flavonoids are secondary metabolites that widely existing in traditional Chinese medicine. They have many biological activities and pharmacological effects. In recent years, studies have found that flavonoids can play an effective protective role in ...
Flavonoids are secondary metabolites that widely existing in traditional Chinese medicine. They have many biological activities and pharmacological effects. In recent years, studies have found that flavonoids can play an effective protective role in ...
2022, 40(2): 103-107, 131.
doi: 10.12206/j.issn.1006-0111.202108002
Abstract:
Hyaluronic acid is widely present in the human body. It is an important component of extracellular matrix. It has unique hydrodynamic properties, good viscoelasticity and strain properties. At present, hyaluronic acid has been widely used in biomater...
Hyaluronic acid is widely present in the human body. It is an important component of extracellular matrix. It has unique hydrodynamic properties, good viscoelasticity and strain properties. At present, hyaluronic acid has been widely used in biomater...
2022, 40(2): 108-112.
doi: 10.12206/j.issn.1006-0111.202105116
Abstract:
Objective To study the reversal effect of Shenfu decoction（SFD）on adriamycin-induced cardiomyopathy and explore its mechanism by using serum metabolomic technology. Methods The BALB/c mouse model of cardiomyopathy induced by adriamycin was es...
2022, 40(2): 113-119.
doi: 10.12206/j.issn.1006-0111.202105106
Abstract:
Objective To explore the mechanism of motherwort in the treatment of nerve injury. Methods The active components of motherwort were obtained by searching TCMSP and BATMAN-TCM databases. The action targets of candidate compounds were collecte...
2022, 40(2): 120-124.
doi: 10.12206/j.issn.1006-0111.202107019
Abstract:
Objective To study the chemical constituents of Aspergillus terreus from sponge epiphytic fungal. Methods Sephadex LH-20 column chromatography, silica gel column chromatography and high performance liquid chroma-tography were used to separate ...
2022, 40(2): 125-131.
doi: 10.12206/j.issn.1006-0111.202111038
Abstract:
Objective To explore the expression of CRELD2 at the gene and protein levels of mouse tissues, and to provide a reference for studying the biological function of CRELD2 in various tissues. Methods The expression level of CRELD2 in the liver, p...
2022, 40(2): 132-135, 142.
doi: 10.12206/j.issn.1006-0111.202110082
Abstract:
Objective To test the cardiac toxicity of new compound HMS-01 and evaluate the safety profile for clinical trials. Methods Manualpatch clamp method was used to measure human Ether-a-go-go-Related Gene (hERG) potassium channel currents with dif...
2022, 40(2): 136-142.
doi: 10.12206/j.issn.1006-0111.202112035
Abstract:
Objective To study the effect and mechanism of epigallocatechol gallate (EGCG) combined with trastuzu-mab on the proliferation of human epidermal growth factor receptor 2 (HER2) overexpressing breast cancer cells. Methods Trastuzumab was exp...
2022, 40(2): 143-145.
doi: 10.12206/j.issn.1006-0111.202101017
Abstract:
Objective To investigate the anti-hyperuricemia effects of Bixie deacidification fang on hyperuricemia mice and its mechanism of renal protein transport. Methods The effects of Bixie deacidification fang were investigated on hyperuricemia mice ...
2022, 40(2): 146-151, 156.
doi: 10.12206/j.issn.1006-0111.202105117
Abstract:
Objective To qualitatively analyze the main chemical components in compound Jinqiancao granules by ultra high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF/MS). Methods XBridge BEH C18 column (2.1 m...
2022, 40(2): 152-156.
doi: 10.12206/j.issn.1006-0111.202106102
Abstract:
Objective To improve the quality standards of Kunxian capsules (KC) and effectively control the product quality. Methods Triptolide, icariin and hypericin were used as the indicator components, to increase or improve the thin layer chromatogra...
2022, 40(2): 157-160, 170.
doi: 10.12206/j.issn.1006-0111.202109050
Abstract:
Objective To revise the determination method in the quality standard of Jingtian Zhitong cream. Methods The total saponins of angelica sinensis, Ligusticum wallichii, Rhizoma corydalis, and Panax notoginseng saponins were qualitatively identif...
2022, 40(2): 161-164.
doi: 10.12206/j.issn.1006-0111.202008007
Abstract:
Objective To establish a high performance liquid chromatography(HPLC) method for simultaneous determination of the contents of 7 components of chlorogenic acid, caffeic acid, paeoniflorin, ammonium glycyrrhizinate, baicalin, baicalein, and wogonin...
2022, 40(2): 165-170.
doi: 10.12206/j.issn.1006-0111.202009087
Abstract:
Objective To investigate the effect of CYP3A5 and MDR1 gene polymorphisms on blood concentration of tacrolimus and creatinine level in uremic patients during the early phase after kidney transplantation in real clinical practice. Methods 131 p...
2022, 40(2): 171-174.
doi: 10.12206/j.issn.1006-0111.202107045
Abstract:
Objective To explore the role of pharmaceutical care in the treatment of patients with pulmonary infection secondary to suppurative thrombophlebitis. Methods The treatment of a patient diagnosed with pulmonary metastatic infection secondary to...
2022, 40(2): 175-179.
doi: 10.12206/j.issn.1006-0111.202109126
Abstract:
Objective To better carries out the review of the interaction between triazole antifungal drugs and statins, ensure drug safety for patients and improve the efficiency of the manual review of pharmacists. Methods The advantageous combination w...
2022, 40(2): 180-183.
doi: 10.12206/j.issn.1006-0111.202106009
Abstract:
Objective To observe the effect of applying PDCA cycle method to promote the management of key monitoring drug, and provide a basis for the management of key monitoring drug in medical institutions. Methods To compare the consumption of drugs ...
2022, 40(2): 184-187.
doi: 10.12206/j.issn.1006-0111.202110068
Abstract:
Objective To explore the needs of community pharmacy services in elderly hypertensive patients in the community, especially empty-nest elderly patients. Methods Elderly hypertensive patients living in Ouyang street were randomly selected and d...
2022, 40(2): 188-192.
doi: 10.12206/j.issn.1006-0111.202105091
Abstract:
Objective To understand the current situation of dispensing errors and effective prevention and control measures in outpatient pharmacies in domestic hospitals, in order to further improve the quality of drug dispensing. Methods The Chinese jo...
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