Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

2022 Vol. 40, No. 4

Cover
Display Method:
Mechanisms and therapeutic drugs of high-altitude lung diseases
HUANG Yueqi, HU Jinglu, LI Qi, LI Miao, XIE Fei, DU Lina, JIN Yiguang
2022, 40(4): 289-295. doi: 10.12206/j.issn.1006-0111.202111025
Abstract(7900) HTML (2064) PDF (1257KB)(99)
Abstract:
The heavily harsh plateau environment including low pressure, hypoxia, cold, dryness and strong ultraviolet radiation, seriously threatens the physical and mental health of those who quickly enter the plateau area. Lungs are the sensitive organs for ...
Progress and perspective of gene therapy
SHI Tong, LI Jizong
2022, 40(4): 296-301, 313. doi: 10.12206/j.issn.1006-0111.202112015
Abstract(14133) HTML (4936) PDF (1006KB)(361)
Abstract:
Gene therapy is generally referred as a therapeutic method through modifying or manipulating gene expression and accordingly changing biological characteristics of living cells. With the substantial progress of vector delivery, gene editing and other...
Research progress and coping strategy of the drug resistant mechanism of platinum anti-tumor drugs
WANG Dongbo, NIE Jing, WU Huina, SUN Lei, LIU Lihui, WU Jiyong
2022, 40(4): 302-308. doi: 10.12206/j.issn.1006-0111.202204046
Abstract(10557) HTML (3989) PDF (1720KB)(206)
Abstract:
Platinum anti-tumor drugs are currently the most widely used first-line chemotherapeutic drugs in clinical practice, and their curative effects are remarkable. However, the problems of platinum drug resistance in non-small cell lung cancer, breast ca...
The role of SDH2 gene in the environmental adaptability of Candida albicans
WANG Xinrong, LU Renyi, WANG Yan
2022, 40(4): 309-313. doi: 10.12206/j.issn.1006-0111.202201096
Abstract(3598) HTML (1177) PDF (1536KB)(30)
Abstract:
Objective  To investigate the role of SDH2 gene in the environmental adaptability of Candida albicans.   Methods  Wild-type C. albicans strain SC5314, SDH2 gene knockout mutant sdh2 Δ/Δ and reintegrated strain sdh2 Δ /SDH2 were used as exper...
Protective effects of the total bakkenolides from Petasites tricholobus on hypoxia mice under normobaric pressure
LI Bingfeng, DUAN Yaqian, WANG Xu, GUO Meili, GAO Yue
2022, 40(4): 314-319. doi: 10.12206/j.issn.1006-0111.202111085
Abstract(3628) HTML (1599) PDF (2432KB)(12)
Abstract:
Objective   To investigate the protective effects of the total bakkenolides from P.tricholobus on improving hypoxia tolerance in mice.   Methods  Mice normobaric pressure hypoxia model and oxygen glucose deprivation model in PC12 cells were establ...
Effect and mechanism of estrogen on EPCs function in diabetic rats
DONG Yafen, WANG Jian, LI Li, LI Shushu, LIU Helong, QIU Yan
2022, 40(4): 320-325. doi: 10.12206/j.issn.1006-0111.202106121
Abstract(3031) HTML (1224) PDF (1381KB)(9)
Abstract:
Objective  To explore the effect and mechanism of estrogen on endothelial progenitor cells(EPCs)function in diabetic rats.   Methods  EPCs were isolated from bone marrow of rats and characterized by fluorescence microscopy and flow cytometry. Rat ...
Role of intercellular junctions in the biological behavior of SP cells of multiple myeloma
WANG Ziyan, ZHANG Xiaohui, RUI Mingzhong, ZHOU Min, FU Jinxiang
2022, 40(4): 326-334. doi: 10.12206/j.issn.1006-0111.202105104
Abstract(3848) HTML (1259) PDF (1833KB)(8)
Abstract:
Objective  To observe the effects of the intercellular gap junction (GJIC) composed of connexin 43(Cx43) in mesenchymal stem cells (MSCs) from different sources and their signals on the biological behavior of multiple myeloma (MM) lateral population...
Investigation of medication adherence for superficial mycoses among students in a college based on Morisky Medication Adherence Scale
TANG Renjie, LI Zhiyong, WANG Ruina, LIU Jiacun, WANG Zhi, LIU Haiyan, LI Honglei, WANG Xu, ZHANG Dazhi, YAN Lan
2022, 40(4): 335-338. doi: 10.12206/j.issn.1006-0111.202107016
Abstract(4472) HTML (1405) PDF (909KB)(19)
Abstract:
Objective  To investigate the medication adherence of military academy students with superficial mycoses.   Methods  A 8-item Morisky medication adherence scale (MMAS) was modified into 7-item scale to evaluate the compliance of antifungal drugs i...
Rapid analysis of chemical components of Xiaotan Tongfu formula based on UHPLC-Q-TOF/MS
QIN Ye, HUANG Wei, GU Yufang, ZHANG Ci’an, XIU Lijuan, TANG Jigui, ZHANG Feng, LIU Xuan
2022, 40(4): 339-346. doi: 10.12206/j.issn.1006-0111.202109029
Abstract(4962) HTML (1720) PDF (1172KB)(21)
Abstract:
Objective  To rapidly explore the chemical components of Xiaotan Tongfu formula, and to provide scientific basis for the basic research and clinical treatment of the formula.   Methods  Analysis was performed on an Agilent 1290 ultra-performance l...
Study on quality standard for Xuanxi Rongjin powder
HU Dan, LIU Chunguang, CAO Hong, ZHANG Guiying, MA Zihui, ZHENG Mingming
2022, 40(4): 347-349, 363. doi: 10.12206/j.issn.1006-0111.202109078
Abstract(2835) HTML (1050) PDF (1812KB)(15)
Abstract:
Objective  To revise the qualitative and quantitative determination methods of Xuanxi Rongjin powder.   Methods  TLC was used to qualitatively identify Chuanxiong and Chuanshanlong. The content of cinnamaldehyde in the preparation was determined ...
Determination of sodium valproate and vancomycin in human serum by HPLC-MS/MS
DUAN Jingjing, JI Guowen, GUO Zhijun, XU Feng
2022, 40(4): 350-353, 378. doi: 10.12206/j.issn.1006-0111.202108087
Abstract(4241) HTML (1430) PDF (970KB)(54)
Abstract:
Objective  To establish a high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for simultaneous determination of sodium valproate and vancomycin in human serum.   Methods  Valproic acid-d6 and kanamycin B were used a...
Cardiovascular benefits of SGLT-2 inhibitors and GLP-1 receptor agonists in type 2 diabetes: a systematic review and network meta-analysis
LAI Yanlan, HUANG Aiwen, CHEN Guanxu, CHEN Tingting, ZHAO Lijun, LIAO Xiaolan, GUO Xiuqiang, WU Gang, SONG Hongtao
2022, 40(4): 354-358. doi: 10.12206/j.issn.1006-0111.202109108
Abstract(4591) HTML (1593) PDF (1098KB)(22)
Abstract:
Objective  To evaluate cardiovascular benefits in patients with type 2 diabetes mellitus treated with the marketed 11 sodium-glucose co-transporter-2 (SGLT-2) inhibitors and glucagon-like polypeptide-1 (GLP-1) receptor agonism by Bayesian network me...
Study on the relationship between blood concentration and efficacy of voriconazole in the treatment of pediatric invasive fungal infection
GUI Mingzhu, LI Jing, XIE Xiaotian, LI Zhiling
2022, 40(4): 359-363. doi: 10.12206/j.issn.1006-0111.202106075
Abstract(3933) HTML (1424) PDF (985KB)(22)
Abstract:
Objective  To explore the correlation between dose, blood concentration and efficacy of voriconazole in the treatment of invasive fungal infection in children.   Methods  68 children treated with voriconazole during January 2019 to December 2019 w...
Case analysis of acute eosinophilic pneumonia caused by recombinant human granulocyte stimulating factor (rhG-CSF)
QU Runan, FAN Jialong, LIU Hui, ZHANG He, MAO Junqin
2022, 40(4): 364-367. doi: 10.12206/j.issn.1006-0111.202202029
Abstract(3202) HTML (1166) PDF (1560KB)(18)
Abstract:
Objective  To investigate the role of clinical pharmacists in identifying adverse drug reactions (ADR), to draw clinical attention to the possibility of drug-induced lung injury caused by rhG-CSF, and distinguish them from infectious diseases.   Me...
Drug monitoring of omalizumab in treatment of 2 children with high level IgE allergic asthma
ZENG Na, WANG Chao, SUN Huajun, MA Liping, DONG Xiaoyan
2022, 40(4): 368-371. doi: 10.12206/j.issn.1006-0111.202205109
Abstract(3875) HTML (2076) PDF (870KB)(9)
Abstract:
Objective  To explore the clinical efficacy and safety of the omalizumab treatment in children with high level IgE allergic asthma.   Methods  The clinical data of 2 children with allergic asthma treated with omalizumab in the Departemnt of Respir...
Perioperative antithrombotic therapy in the patient undergoing revision total hip arthroplasty after coronary stent implantation: a case report and literature review
LI Ying, CAO Ailin, BAO Leilei, WANG Zhankun, QIAN Jiao
2022, 40(4): 372-373, 386. doi: 10.12206/j.issn.1006-0111.202103074
Abstract(2877) HTML (1061) PDF (819KB)(21)
Abstract:
Objective  To explore the strategies of perioperative antithrombotic therapy in the patient undergoing revision total hip arthroplasty after coronary stent implantation.   Methods  The antithrombotic therapy in one patient undergoing revision tota...
Implementation and exploration of administration of anesthesia and psychotropic drugs by electronic account books
GE Jiyun, ZHANG Jing, WANG Liling, YAO Chen, BAO Leilei, HUANG Yufeng
2022, 40(4): 374-378. doi: 10.12206/j.issn.1006-0111.202109089
Abstract(3573) HTML (1218) PDF (3208KB)(30)
Abstract:
Objective  To explore the effect and significance of electronic account books on the management of anesthesia and psychotropic drugs.  Methods  The data of electronic account books from January 2020 to June 2020 in the inpatient pharmacy of the ho...
Retrospective analysis of the pre-audit results for prescriptions of Chinese patent medicines in a second-level hospital
XU Shanshan, FU Xiang
2022, 40(4): 379-382. doi: 10.12206/j.issn.1006-0111.202111089
Abstract(3252) HTML (1140) PDF (854KB)(13)
Abstract:
Objective  Analyze the pre-audit results of Chinese patent medicine prescriptions in a second-level hospital, suggest the risks of taking Chinese patent medicines and promote the safe and standardized use of Chinese patent medicines.   Methods  A ...
Suggestions on the revision of pharmacist examination outline for national professional qualification examination of licensed pharmacists
WEN Ruirui, XU Long, ZHU Wenjing
2022, 40(4): 383-386. doi: 10.12206/j.issn.1006-0111.202202025
Abstract(3331) HTML (930) PDF (901KB)(5)
Abstract:
This paper summarized the implementation of the pharmacist examination outline of the seventh edition of the national professional qualification examination for licensed pharmacists, and pointed out the existing problems and deficiencies: unclear def...
2022, 40(4): 387-388. doi: 10.12206/j.issn.1006-0111.202109137
Abstract(3657) HTML (1778) PDF (786KB)(38)
Abstract: