2022 Vol. 40, No. 4
Display Method:
2022, 40(4): 289-295.
doi: 10.12206/j.issn.1006-0111.202111025
Abstract:
The heavily harsh plateau environment including low pressure, hypoxia, cold, dryness and strong ultraviolet radiation, seriously threatens the physical and mental health of those who quickly enter the plateau area. Lungs are the sensitive organs for ...
The heavily harsh plateau environment including low pressure, hypoxia, cold, dryness and strong ultraviolet radiation, seriously threatens the physical and mental health of those who quickly enter the plateau area. Lungs are the sensitive organs for ...
2022, 40(4): 296-301, 313.
doi: 10.12206/j.issn.1006-0111.202112015
Abstract:
Gene therapy is generally referred as a therapeutic method through modifying or manipulating gene expression and accordingly changing biological characteristics of living cells. With the substantial progress of vector delivery, gene editing and other...
Gene therapy is generally referred as a therapeutic method through modifying or manipulating gene expression and accordingly changing biological characteristics of living cells. With the substantial progress of vector delivery, gene editing and other...
2022, 40(4): 302-308.
doi: 10.12206/j.issn.1006-0111.202204046
Abstract:
Platinum anti-tumor drugs are currently the most widely used first-line chemotherapeutic drugs in clinical practice, and their curative effects are remarkable. However, the problems of platinum drug resistance in non-small cell lung cancer, breast ca...
Platinum anti-tumor drugs are currently the most widely used first-line chemotherapeutic drugs in clinical practice, and their curative effects are remarkable. However, the problems of platinum drug resistance in non-small cell lung cancer, breast ca...
2022, 40(4): 309-313.
doi: 10.12206/j.issn.1006-0111.202201096
Abstract:
Objective To investigate the role of SDH2 gene in the environmental adaptability of Candida albicans. Methods Wild-type C. albicans strain SC5314, SDH2 gene knockout mutant sdh2 Δ/Δ and reintegrated strain sdh2 Δ /SDH2 were used as exper...
2022, 40(4): 314-319.
doi: 10.12206/j.issn.1006-0111.202111085
Abstract:
Objective To investigate the protective effects of the total bakkenolides from P.tricholobus on improving hypoxia tolerance in mice. Methods Mice normobaric pressure hypoxia model and oxygen glucose deprivation model in PC12 cells were establ...
2022, 40(4): 320-325.
doi: 10.12206/j.issn.1006-0111.202106121
Abstract:
Objective To explore the effect and mechanism of estrogen on endothelial progenitor cells(EPCs)function in diabetic rats. Methods EPCs were isolated from bone marrow of rats and characterized by fluorescence microscopy and flow cytometry. Rat ...
2022, 40(4): 326-334.
doi: 10.12206/j.issn.1006-0111.202105104
Abstract:
Objective To observe the effects of the intercellular gap junction (GJIC) composed of connexin 43(Cx43) in mesenchymal stem cells (MSCs) from different sources and their signals on the biological behavior of multiple myeloma (MM) lateral population...
2022, 40(4): 335-338.
doi: 10.12206/j.issn.1006-0111.202107016
Abstract:
Objective To investigate the medication adherence of military academy students with superficial mycoses. Methods A 8-item Morisky medication adherence scale (MMAS) was modified into 7-item scale to evaluate the compliance of antifungal drugs i...
2022, 40(4): 339-346.
doi: 10.12206/j.issn.1006-0111.202109029
Abstract:
Objective To rapidly explore the chemical components of Xiaotan Tongfu formula, and to provide scientific basis for the basic research and clinical treatment of the formula. Methods Analysis was performed on an Agilent 1290 ultra-performance l...
2022, 40(4): 347-349, 363.
doi: 10.12206/j.issn.1006-0111.202109078
Abstract:
Objective To revise the qualitative and quantitative determination methods of Xuanxi Rongjin powder. Methods TLC was used to qualitatively identify Chuanxiong and Chuanshanlong. The content of cinnamaldehyde in the preparation was determined ...
2022, 40(4): 350-353, 378.
doi: 10.12206/j.issn.1006-0111.202108087
Abstract:
Objective To establish a high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method for simultaneous determination of sodium valproate and vancomycin in human serum. Methods Valproic acid-d6 and kanamycin B were used a...
2022, 40(4): 354-358.
doi: 10.12206/j.issn.1006-0111.202109108
Abstract:
Objective To evaluate cardiovascular benefits in patients with type 2 diabetes mellitus treated with the marketed 11 sodium-glucose co-transporter-2 (SGLT-2) inhibitors and glucagon-like polypeptide-1 (GLP-1) receptor agonism by Bayesian network me...
2022, 40(4): 359-363.
doi: 10.12206/j.issn.1006-0111.202106075
Abstract:
Objective To explore the correlation between dose, blood concentration and efficacy of voriconazole in the treatment of invasive fungal infection in children. Methods 68 children treated with voriconazole during January 2019 to December 2019 w...
2022, 40(4): 364-367.
doi: 10.12206/j.issn.1006-0111.202202029
Abstract:
Objective To investigate the role of clinical pharmacists in identifying adverse drug reactions (ADR), to draw clinical attention to the possibility of drug-induced lung injury caused by rhG-CSF, and distinguish them from infectious diseases. Me...
2022, 40(4): 368-371.
doi: 10.12206/j.issn.1006-0111.202205109
Abstract:
Objective To explore the clinical efficacy and safety of the omalizumab treatment in children with high level IgE allergic asthma. Methods The clinical data of 2 children with allergic asthma treated with omalizumab in the Departemnt of Respir...
2022, 40(4): 372-373, 386.
doi: 10.12206/j.issn.1006-0111.202103074
Abstract:
Objective To explore the strategies of perioperative antithrombotic therapy in the patient undergoing revision total hip arthroplasty after coronary stent implantation. Methods The antithrombotic therapy in one patient undergoing revision tota...
2022, 40(4): 374-378.
doi: 10.12206/j.issn.1006-0111.202109089
Abstract:
Objective To explore the effect and significance of electronic account books on the management of anesthesia and psychotropic drugs. Methods The data of electronic account books from January 2020 to June 2020 in the inpatient pharmacy of the ho...
2022, 40(4): 379-382.
doi: 10.12206/j.issn.1006-0111.202111089
Abstract:
Objective Analyze the pre-audit results of Chinese patent medicine prescriptions in a second-level hospital, suggest the risks of taking Chinese patent medicines and promote the safe and standardized use of Chinese patent medicines. Methods A ...
2022, 40(4): 383-386.
doi: 10.12206/j.issn.1006-0111.202202025
Abstract:
This paper summarized the implementation of the pharmacist examination outline of the seventh edition of the national professional qualification examination for licensed pharmacists, and pointed out the existing problems and deficiencies: unclear def...
This paper summarized the implementation of the pharmacist examination outline of the seventh edition of the national professional qualification examination for licensed pharmacists, and pointed out the existing problems and deficiencies: unclear def...