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2022 Vol. 40, No. 5

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Establishment of SLC6A4 gene silencing stable cell line in PC12 cells and the effect of SLC6A4 gene silencing on apoptosis of hypoxia PC12 cells
ZHANG Dongmei, GAO Yingchun, HE Lei, CHEN Keming, LI Wenbin, WANG Rong, MA Huiping
2022, 40(5): 389-394, 463. doi: 10.12206/j.issn.2097-2024.202205093
Abstract(4718) HTML (3202) PDF (2814KB)(38)
Abstract:
Objective  To construct SLC6A4-shRNA lentiviral vector, establish PC12 cells stable transformation cell line, and detect the effect of SLC6A4 gene silencing on hypoxia induced PC12 cells apoptosis.   Methods  Three specific targets sequence of SLC...
Clinical trial of nifedipine controlled-release tablets on reducing blood pressure in the treatment of patients with hypertension at high altitude
HUANG Qin, GAO Zizhao, NIYANG Zhuoma, SUONAN Gele, WANG Rong
2022, 40(5): 395-398. doi: 10.12206/j.issn.2097-2024.202205112
Abstract(3228) HTML (1154) PDF (861KB)(16) Cited By (1)
Abstract:
Objective   To observe the clinical efficacy and safety of nifedipine controlled-release tablets on the antihypertensive effect of hypertensive patients under high altitude environment.   Methods  42 hypertensive inpatients in the 940th hospital (...
A preliminary study on the mechanism of 7-HEC on high altitude cerebral edema
SHI Zhiqun, GAO Yingchun, ZHANG Dongmei, CHEN Keming, JING Linlin, MA Huiping
2022, 40(5): 399-402, 415. doi: 10.12206/j.issn.2097-2024.202205090
Abstract(3599) HTML (1094) PDF (1199KB)(10) Cited By (1)
Abstract:
Objective  To study the possible mechanism of 7-hydroxyethyl chrysin (7-HEC) on high altitude cerebral edema (HACE).   Methods  A rat model of high altitude cerebral edema was established. The activity of superoxide dismutase (SOD) and the content...
Protective effect of Saussurea involucrata flavone capsule on myocardial injury induced by hypoxia at high altitude in mice
ZHANG Pengpeng, LI Lin, SHI ZhiQun, HE Lei, MA Huiping
2022, 40(5): 403-407, 432. doi: 10.12206/j.issn.2097-2024.202205086
Abstract(4093) HTML (1027) PDF (2337KB)(9)
Abstract:
Objective  To study the protective effect and mechanism of Saussurea involucrata flavone capsule on the myocardial tissue of mice in simulated plateau hypoxia environment.   Methods  64 Balb/c mice were randomly divided into normal control group, ...
Research progress of Tibetan medicine against plateau hypoxia
WANG Zihan, ZHAO Anpeng, MU Hongfang, GUO Qianwen, CHENG Junfei, WANG Rong
2022, 40(5): 408-415. doi: 10.12206/j.issn.2097-2024.202205094
Abstract(9031) HTML (3437) PDF (1077KB)(53) Cited By (2)
Abstract:
Tibetan is a kind of medicine which extensively absorbed and fused the Chinese Traditional Medicine, Indian medicine and food through long-term practice and form the unique medical system. At the same time, the Qinghai Tibet plateau has characteristi...
Research progress of atorvastatin gene polymorphism
HUANG Qin, SUONAN Gele, LI Wenbin, SUN Yuemei, WANG Rong
2022, 40(5): 416-421, 426. doi: 10.12206/j.issn.2097-2024.202110042
Abstract(7957) HTML (3654) PDF (1223KB)(70)
Abstract:
Atorvastatin is a blood lipid-lowering drug widely used clinically. Long-term use can prevent and reduce the occurrence of atherosclerotic cardiovascular disease (ASCVD). However, the efficacy of atorvastatin has significant inter-individual differen...
Advances in antidepressant therapy related to gut microbiota
WANG Qiannan, HUANG Xinhui, YANG Minxu, YANG Xingrui, ZHU Kehan, ZHOU Tingting
2022, 40(5): 422-426. doi: 10.12206/j.issn.2097-2024.202111034
Abstract(8158) HTML (2457) PDF (984KB)(35)
Abstract:
Objective   This paper introduces the research progress on the pathogenesis of depression related to gut microbiota and provides the resources for the subsequent development of antidepressant drugs targeting gut microbiota.   Methods  33 literatur...
Research progress of anti-radiation natural products
YAO Yiqing, FANG Jiahao, MA Huilin, WANG Xuan, LYU Diya
2022, 40(5): 427-432. doi: 10.12206/j.issn.2097-2024.202101033
Abstract(7693) HTML (2834) PDF (1003KB)(141) Cited By (5)
Abstract:
With the rapid developments of science and technology, the diagnosis technology based on nuclear physics and radiotherapy technology are widely used in medicine, but radiation at the same time could have different levels of damage to human body. Ther...
Overview and prospects of great health products of traditional Chinese medicine for anti-epidemic application
HAN Jianyong, JIANG Yiping, HAN Ting, XIN Hailiang
2022, 40(5): 433-436, 441. doi: 10.12206/j.issn.2097-2024.202103015
Abstract(7162) HTML (2478) PDF (927KB)(37)
Abstract:
Anti-epidemic traditional Chinese medicine health products are in line with the Healthy China strategy, play an important role in epidemic prevention and control, with adantages of diverse types, obvious effects, easy acceptance, and convenient admin...
Preparation and characterization of photosensitive ROS-responsive rapamycin liposomes
GAO Xiqing, LU Guangzhao, LU Ying, ZOU Hao
2022, 40(5): 437-441. doi: 10.12206/j.issn.2097-2024.202110051
Abstract(6571) HTML (1625) PDF (1424KB)(51) Cited By (3)
Abstract:
Objective  To study the preparation process and properties of photosensitive ROS (Reactive oxygen species) responsive rapamycin liposome, and to develop a stable and efficient stimulus-responsive liposome carrier.   Methods  Rapamycin liposomes we...
Anti-inflammatory and analgesic study of Yinlian Tongfeng granules on adjuvant arthritis rats
LIU Jing, XU Yi, WU Tiejun, HUANG Jin
2022, 40(5): 442-445, 476. doi: 10.12206/j.issn.2097-2024.202103005
Abstract(2856) HTML (1358) PDF (953KB)(17)
Abstract:
Objective  To investigate the relieving effect of Yinlian Tongfeng granules on adjuvant arthritis rats.   Methods  A complete Freund adjuvant model was built for this study. 48 rats were randomly divided into control group, model group, Yinlian To...
Identification of chemical constituents and blood-absorbed ingredients of FeiPi QiXu decoction by UHPLC-Q-TOF/MS
WU Jin, ZHAO Jing, PANG Tao
2022, 40(5): 446-453. doi: 10.12206/j.issn.2097-2024.202204079
Abstract(5291) HTML (2434) PDF (1271KB)(68) Cited By (5)
Abstract:
Objective   To identify the chemical constituents and blood-absorbed ingredients of FeiPi QiXu decoction, and provide reference for clarifying the material basis of its efficacy.   Methods  An ultrahigh performance liquid chromatography-quadrupole...
Comparative analysis of medicines varieties and dosage forms between UAE and China
ZHU Kehan, CHEN Jing
2022, 40(5): 454-463. doi: 10.12206/j.issn.2097-2024.202207059
Abstract(3931) HTML (1512) PDF (1044KB)(10) Cited By (5)
Abstract:
Objective  To understand the supply situation of the UAE’s medicinal market and provide reference for Chinese medicines which are going to import into the UAE.   Methods  The data related to the existing varieties and dosage forms in the UAE’s med...
Study on quality standard and characteristic chromatogram for Hirtula Roses
ZHANG Chengzhong, ZHENG Chengjian, HE Xuhui, WANG Hongrui, HUANG Baokang, BU Qitao
2022, 40(5): 464-468. doi: 10.12206/j.issn.2097-2024.202106104
Abstract(5480) HTML (2328) PDF (1309KB)(31) Cited By (1)
Abstract:
Objective  To establish the quality standards of Hirtula Roses for the quality control of production, supervision, circulation and application.   Methods  The moisture content, total ash, ethanol extract content and characteristic chromatogram of ...
Predictive value of neutrophil to lymphocyte ratio combined with BNP in elderly patients with heart failure complicated with pulmonary infection
ZHANG Jie, CHAO Shengwu, YANG Jishun
2022, 40(5): 469-472. doi: 10.12206/j.issn.2097-2024.202112010
Abstract(3749) HTML (1222) PDF (1012KB)(11) Cited By (3)
Abstract:
Objective   To evaluate the predictive value of neutrophil to lymphocyte ratio(NLR) and B-type natriuretic peptide (BNP) in elderly patients with heart failure complicated with pulmonary infection.   Methods  178 heart failure patients in our hosp...
Pharmaceutical care of a patient with type 2 diabetes and osteoporosis
LUO Jinqian, LU Songwei, TIAN Jing, YU Huihua
2022, 40(5): 473-476. doi: 10.12206/j.issn.2097-2024.202110024
Abstract(4035) HTML (1469) PDF (935KB)(40) Cited By (1)
Abstract:
Objective  To investigate the disease characteristics and key factors of pharmaceutical care in patients with diabetes and osteoporosis, and provide references for clinical rational and effective medication.   Methods  Clinical pharmacist particip...
Pharmaceutical care in a case of patient with Pneumocystis jiroveci pneumonia after renal transplantation
ZHANG Chunyan, GONG Zhenqiong
2022, 40(5): 477-480. doi: 10.12206/j.issn.2097-2024.202108037
Abstract(3745) HTML (1665) PDF (888KB)(17) Cited By (3)
Abstract:
Objective  To discuss the role of clinical pharmacist in individualized treatment and pharmaceutical care for a patient with Pneumocystis jiroveci pneumonia after renal transplantation.   Methods  The clinical pharmacist participated in the pharma...
Observation on the effect of Kunxian capsule combined with candesartan cilexetil in the treatment of chronic nephritis with hypertension
ZHAO Linna, LIU Li, LI Hongyan, SUN Wencai, WU Wen, DONG Xuebin
2022, 40(5): 481-484. doi: 10.12206/j.issn.2097-2024.202105112
Abstract(3918) HTML (1555) PDF (884KB)(13)
Abstract:
Objective  To investigate the effect of Kunxian capsule combined with candesartan axetil on blood pressure, renal function, blood lipids and inflammatory factors in patients with chronic glomerulonephritis complicated with hypertension.   Methods ...