2016 Vol. 34, No. 1
Display Method:
2016, 34(1): 1-4,55.
doi: 10.3969/j.issn.1006-0111.2016.01.001
Abstract:
Breast cancer has become the main malignant tumors which pose a serious threat to women's health.Selective estrogen receptor modulators, which served as the effective drug treatment,have been attracting more attention. Present research progress on th...
Breast cancer has become the main malignant tumors which pose a serious threat to women's health.Selective estrogen receptor modulators, which served as the effective drug treatment,have been attracting more attention. Present research progress on th...
2016, 34(1): 5-7,15.
doi: 10.3969/j.issn.1006-0111.2016.01.002
Abstract:
Glycosylation is the key step of the synthesis of GM3, its reaction conditions are very harsh, the stereoselectivities are usually poor, and the configuration of anomeric carbon is difficult to control. Whether α glycosidic bond can be constructed ef...
Glycosylation is the key step of the synthesis of GM3, its reaction conditions are very harsh, the stereoselectivities are usually poor, and the configuration of anomeric carbon is difficult to control. Whether α glycosidic bond can be constructed ef...
2016, 34(1): 8-11,47.
doi: 10.3969/j.issn.1006-0111.2016.01.003
Abstract:
The occurrence of the clinical manifestations of myocardial ischemia shows clear circadian rhythmicity, and they are unevenly distributed during the 24 h with higher morbidity during the initial hours of the daily activity span and in the late aftern...
The occurrence of the clinical manifestations of myocardial ischemia shows clear circadian rhythmicity, and they are unevenly distributed during the 24 h with higher morbidity during the initial hours of the daily activity span and in the late aftern...
2016, 34(1): 12-15.
doi: 10.3969/j.issn.1006-0111.2016.01.004
Abstract:
Inflammasome is the body of protein complex which is able to identify different stimulation signals and can induce immune and inflammatory responses when it is activated. NLRP3 inflammasome has been extensively studied in the central nervous system. ...
Inflammasome is the body of protein complex which is able to identify different stimulation signals and can induce immune and inflammatory responses when it is activated. NLRP3 inflammasome has been extensively studied in the central nervous system. ...
2016, 34(1): 16-18.
doi: 10.3969/j.issn.1006-0111.2016.01.005
Abstract:
Objective This article reviewed the moisture-proof strategies of Chinese meteria medica preparation to provide a basis for quality control of traditional Chinese medicine. Methods Review, analyze and summarize through referring to relevant literat...
Objective This article reviewed the moisture-proof strategies of Chinese meteria medica preparation to provide a basis for quality control of traditional Chinese medicine. Methods Review, analyze and summarize through referring to relevant literat...
2016, 34(1): 19-23,40.
doi: 10.3969/j.issn.1006-0111.2016.01.006
Abstract:
Objective To study and optimize the preparation condition of pVAX1-wapA-loaded nanoparticles and determine the transfection efficiency. Methods The related effects of the crucial factors for the formation of nanoparticles: concentration of chitosa...
Objective To study and optimize the preparation condition of pVAX1-wapA-loaded nanoparticles and determine the transfection efficiency. Methods The related effects of the crucial factors for the formation of nanoparticles: concentration of chitosa...
2016, 34(1): 24-27,51.
doi: 10.3969/j.issn.1006-0111.2016.01.007
Abstract:
Objective To study the chemical constituents of Ixeris sonchifolia. Methods Monomeric compounds were isolated by chromatography on silica gel column, Sephadex LH-20, ODS chromatography column and HPLC.Thestructure of the compound wasconfirmed on t...
Objective To study the chemical constituents of Ixeris sonchifolia. Methods Monomeric compounds were isolated by chromatography on silica gel column, Sephadex LH-20, ODS chromatography column and HPLC.Thestructure of the compound wasconfirmed on t...
2016, 34(1): 28-31,61.
doi: 10.3969/j.issn.1006-0111.2016.01.008
Abstract:
Objective To study the effect of coptis decoction on rats with ulcerative colitis. Methods Rat ulcerative colitis model was induced by 1,2-dimethylhydrazine(DMH)(40 mg/kg s.c.)+3% dextran sodium sulfate solution(DSS)(freely drinking). The drugs we...
Objective To study the effect of coptis decoction on rats with ulcerative colitis. Methods Rat ulcerative colitis model was induced by 1,2-dimethylhydrazine(DMH)(40 mg/kg s.c.)+3% dextran sodium sulfate solution(DSS)(freely drinking). The drugs we...
2016, 34(1): 32-35,65.
doi: 10.3969/j.issn.1006-0111.2016.01.009
Abstract:
Objective To investigate the hemostatic effect of Bletillastriata hemostatic sponge. Methods Tail hemorrhage model in rats was preparation. Another model was established in liver and spleen hemorrhagic model of rabbits, Beagle dog's abdominal aort...
Objective To investigate the hemostatic effect of Bletillastriata hemostatic sponge. Methods Tail hemorrhage model in rats was preparation. Another model was established in liver and spleen hemorrhagic model of rabbits, Beagle dog's abdominal aort...
2016, 34(1): 36-40.
doi: 10.3969/j.issn.1006-0111.2016.01.010
Abstract:
Objective To prepare gemcitabine hydrochloride thermosensitive gel injection and to stablish the determination methods of its contents. Methods Gemcitabine hydrochloride thermosensitive gel injection was prepared using PLGA-PEG-PLGA as thermosensi...
Objective To prepare gemcitabine hydrochloride thermosensitive gel injection and to stablish the determination methods of its contents. Methods Gemcitabine hydrochloride thermosensitive gel injection was prepared using PLGA-PEG-PLGA as thermosensi...
2016, 34(1): 41-43,75.
doi: 10.3969/j.issn.1006-0111.2016.01.011
Abstract:
Objective To develop a simple and sensitive HPLC-UV method to determined actarit in plasma. Methods The chromatographic separation was carried out on a Dikma C18 column with a mobile phase composed of water containing 1.2% acetic acid-methanol (50...
Objective To develop a simple and sensitive HPLC-UV method to determined actarit in plasma. Methods The chromatographic separation was carried out on a Dikma C18 column with a mobile phase composed of water containing 1.2% acetic acid-methanol (50...
2016, 34(1): 44-47.
doi: 10.3969/j.issn.1006-0111.2016.01.012
Abstract:
Objective To prepare hot-melt pressure sensitive adhesive (HMPSA) transdermal patches of progesterone and investigate the release characterization in vitro. Methods SIS HMPSA was used as matrix material, modified Franz diffusion cell and excised f...
Objective To prepare hot-melt pressure sensitive adhesive (HMPSA) transdermal patches of progesterone and investigate the release characterization in vitro. Methods SIS HMPSA was used as matrix material, modified Franz diffusion cell and excised f...
2016, 34(1): 48-51.
doi: 10.3969/j.issn.1006-0111.2016.01.013
Abstract:
Objective To establish a method for the determination of quetiapine fumarate in human serum by RP-HPLC and apply it into clinical. Methods Extracting with ethyl ether after serum-drug was alkalized, and then determined by RP-HPLC. The determinatio...
Objective To establish a method for the determination of quetiapine fumarate in human serum by RP-HPLC and apply it into clinical. Methods Extracting with ethyl ether after serum-drug was alkalized, and then determined by RP-HPLC. The determinatio...
2016, 34(1): 52-55.
doi: 10.3969/j.issn.1006-0111.2016.01.014
Abstract:
Objective To establish a method for determining volatile components from Actinidia valvata Dunn. Methods A static headspace-gas chromatography-mass spectrometry (HS-GC-MS) method was used to analyze volatile components,and the separated peaks were...
Objective To establish a method for determining volatile components from Actinidia valvata Dunn. Methods A static headspace-gas chromatography-mass spectrometry (HS-GC-MS) method was used to analyze volatile components,and the separated peaks were...
2016, 34(1): 56-58,78.
doi: 10.3969/j.issn.1006-0111.2016.01.015
Abstract:
Objective To investigate the constituents and analgesic and anti-inflammatory effects of leaves essential oil in Schefflera octophylla. Methods SOLEO was dilated by water vapor. The mouse acetic acid-induced twisting test and mouse auricle swellin...
Objective To investigate the constituents and analgesic and anti-inflammatory effects of leaves essential oil in Schefflera octophylla. Methods SOLEO was dilated by water vapor. The mouse acetic acid-induced twisting test and mouse auricle swellin...
2016, 34(1): 59-61.
doi: 10.3969/j.issn.1006-0111.2016.01.016
Abstract:
Objective To establish the method for determination content of glycine in the pharmaceutical of human coagulation factor Ⅷ by HPLC. Methods The analysis was carried on a Shim-Pack CLC-ODS column with a mobile phase of 50% acetonitrile -0.05 mol/L ...
Objective To establish the method for determination content of glycine in the pharmaceutical of human coagulation factor Ⅷ by HPLC. Methods The analysis was carried on a Shim-Pack CLC-ODS column with a mobile phase of 50% acetonitrile -0.05 mol/L ...
2016, 34(1): 62-65.
doi: 10.3969/j.issn.1006-0111.2016.01.017
Abstract:
Objective To compare two methods in the determination of mannatide for injection. Methods The contents were determined by spectrophotometry and HPLC method. Results In the samples determined by Spectrophotometric Determination,soluble in phenol ...
Objective To compare two methods in the determination of mannatide for injection. Methods The contents were determined by spectrophotometry and HPLC method. Results In the samples determined by Spectrophotometric Determination,soluble in phenol ...
2016, 34(1): 66-71.
doi: 10.3969/j.issn.1006-0111.2016.01.018
Abstract:
Objective To establish the quality standard for Quban oral liquid. Method Thin layer chromatography(TLC)was used for quality identification of Codonopsis pilosula, Astragalus membranaceus, Paeonia veitchii, Paeonia lactiflora, Atractylodes macroce...
Objective To establish the quality standard for Quban oral liquid. Method Thin layer chromatography(TLC)was used for quality identification of Codonopsis pilosula, Astragalus membranaceus, Paeonia veitchii, Paeonia lactiflora, Atractylodes macroce...
2016, 34(1): 72-75.
doi: 10.3969/j.issn.1006-0111.2016.01.019
Abstract:
Objective To improve the quality control standard of lidocaine hydrochloride injection. Methods A method for determination of related substances in lidocaine hydrochloride injection was established. Lidocaine hydrochloride was assayed by HPLC. The...
Objective To improve the quality control standard of lidocaine hydrochloride injection. Methods A method for determination of related substances in lidocaine hydrochloride injection was established. Lidocaine hydrochloride was assayed by HPLC. The...
2016, 34(1): 76-78.
doi: 10.3969/j.issn.1006-0111.2016.01.020
Abstract:
Objective To study the microorganism viability in compound resorcinol lotion, confirming with bactericidal compound resorcinol lotion. Methods 5 bottles of compound resorcinol lotion were respectively added Escherichia coli, Staphylococcus aureus,...
Objective To study the microorganism viability in compound resorcinol lotion, confirming with bactericidal compound resorcinol lotion. Methods 5 bottles of compound resorcinol lotion were respectively added Escherichia coli, Staphylococcus aureus,...
2016, 34(1): 79-82,92.
doi: 10.3969/j.issn.1006-0111.2016.01.021
Abstract:
Objective To evaluate traditional Chinese medicine (TCM) formula granules of clear heat evil and detoxification treating hyperuricemia clinical efficacy and safety through randomized, placebo controlled, blinded clinical trial. Methods 120 patient...
Objective To evaluate traditional Chinese medicine (TCM) formula granules of clear heat evil and detoxification treating hyperuricemia clinical efficacy and safety through randomized, placebo controlled, blinded clinical trial. Methods 120 patient...
2016, 34(1): 83-85,89.
doi: 10.3969/j.issn.1006-0111.2016.01.022
Abstract:
Objective The aim of the study is to evaluate clinical efficacy and safety of azatreonam or ceftazidime on treatment of lower respiratory tract infection. Methods Four English databases (MEDLINE、EMBASE、Pubmed、Cochrane library) and three Chinese da...
Objective The aim of the study is to evaluate clinical efficacy and safety of azatreonam or ceftazidime on treatment of lower respiratory tract infection. Methods Four English databases (MEDLINE、EMBASE、Pubmed、Cochrane library) and three Chinese da...
2016, 34(1): 86-89.
doi: 10.3969/j.issn.1006-0111.2016.01.023
Abstract:
Objective To investigate the application situation and analyze the main characters and developing tendency of anti-neoplastic drugs in some hospital. Methods To collect the frequency and the consumption sum of anti-neoplastic drugs used in this ho...
Objective To investigate the application situation and analyze the main characters and developing tendency of anti-neoplastic drugs in some hospital. Methods To collect the frequency and the consumption sum of anti-neoplastic drugs used in this ho...
2016, 34(1): 90-92.
doi: 10.3969/j.issn.1006-0111.2016.01.024
Abstract:
Objective To monitor the medication process of advanced lung cancer patients with renal insufficiency. Methods Pharmaceutical care, pharmaceutical intervention and medication were offered according to the individual condition of patient with renal...
Objective To monitor the medication process of advanced lung cancer patients with renal insufficiency. Methods Pharmaceutical care, pharmaceutical intervention and medication were offered according to the individual condition of patient with renal...
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