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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状

李园园 于锋

李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
引用本文: 李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
Citation: LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005

哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状

doi: 10.3969/j.issn.1006-0111.2014.06.005

Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium

  • 摘要: 目的 为哌拉西林钠-他唑巴坦钠的临床合理用药提供参考。 方法 对哌拉西林钠-他唑巴坦钠的优选给药方案的药动/药效学研究、临床试验及具体实施情况进行综述。 结果 哌拉西林钠-他唑巴坦钠的优选给药方案(延长输注或持续输注)可最大化地达到药效学目标,改善临床有效性。 结论 需积极完善优化方案用于临床实践的策略。
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    [23] Patel N, Scheetz MH, Drusano GL, et al. Identification of optimal renal dosage adjustments for traditional and extended-infusion piperacillin-tazobactam dosing regimens in hospitalized patients[J].Antimicrob Agents Chemother, 2010, 54(1): 460-465.
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    [25] Grant EM, Kuti JL, Nicolau DP, et al. Clinical efficacy and pharmacoeconomics of a continuous-infusion piperacillin-tazobactam program in a large community teaching hospital[J].Pharmacotherapy, 2002, 22(4): 471-483.
    [26] Florea NR, Kotapati S, Kuti JL, et al. Cost analysis of continuous versus intermittent infusion of piperacillin-tazobactam: a time-motion study[J].Am J Health Syst Pharm, 2003, 60(22): 2321-2327.
    [27] Lodise TP, Jr, Lomaestro B, Drusano GL. Piperacillin-tazobactam for Pseudomonas aeruginosa infection: clinical implications of an extended-infusion dosing strategy[J].Clin Infect Dis, 2007, 44(3): 357-363.
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    [29] 叶龙强, 蔡 挺, 金雨虹, 等. 延长哌拉西林/他唑巴坦输注时间治疗革兰阴性杆菌感染的临床研究[J].中华医院感染学杂志, 2011, 21(16): 3476-3479.
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  • 收稿日期:  2013-07-21
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哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状

doi: 10.3969/j.issn.1006-0111.2014.06.005

摘要: 目的 为哌拉西林钠-他唑巴坦钠的临床合理用药提供参考。 方法 对哌拉西林钠-他唑巴坦钠的优选给药方案的药动/药效学研究、临床试验及具体实施情况进行综述。 结果 哌拉西林钠-他唑巴坦钠的优选给药方案(延长输注或持续输注)可最大化地达到药效学目标,改善临床有效性。 结论 需积极完善优化方案用于临床实践的策略。

English Abstract

李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
引用本文: 李园园, 于锋. 哌拉西林钠-他唑巴坦钠优选给药方案的评估及应用的研究现状[J]. 药学实践与服务, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
Citation: LI Yuanyuan, YU Feng. Current situation of evaluation and application with alternative dosing regimens for piperacillin sodium-tazobactam sodium[J]. Journal of Pharmaceutical Practice and Service, 2014, 32(6): 416-418,452. doi: 10.3969/j.issn.1006-0111.2014.06.005
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