Research on potentially inappropriate medication use in elderly patients:based on the clinical use of Criteria of potentially inappropriate medications for older adults in China(2017)
-
摘要: 目的 通过分析养老机构老年多重用药患者潜在不适当用药的现状,为临床药师推进老年患者的合理用药提供参考依据。 方法 随机抽取上海某养老机构老年多重用药患者258例,以《中国老年人潜在不适当用药判断标准(2017版)》为评价依据进行分析,总结检出的潜在不适当用药(PIM)情况。 结果 研究对象的平均年龄为(82.57±5.56)岁,平均服药种数(6.98±1.96)种,共检出160名(62.0%)患者存在PIM。其中,与药物有关的潜在不适当用药206项,与疾病状态有关的潜在不适当用药91项。 结论 养老机构老年多重用药患者潜在不适当用药情况突出,临床药师依托多学科评估团队介入药物治疗,对发现和消除PIM及优化用药方案起到重要作用。Abstract: Objective To provide reference for clinical pharmacists to promote rational medication use in elderly patients by analyzing the current situation of elderly patients with multiple medication use in nursing institution. Methods A total of 258 elderly patients with multiple medication use were randomly selected from a nursing institution in Shanghai.Based on Criteria of potentially inappropriate medications for older adults in China,the situation of potential inappropriate medication use (PIM) were analyzed and summarized. Results The average age of subjects was (82.57±5.56) years old,and the average number of medication use was (6.98±1.96).A total of 160 (62.0%) patients were detected with PIM.Among them,206 were potential inappropriate medications related to medications and 91 were potential inappropriate medications related to disease status. Conclusion Potential inappropriate use of medication was serious in elderly patients with multiple medication use in nursing institution.Clinical pharmacists should rely on multidisciplinary evaluation teams to intervene in medication treatment,which would play an important role in discover and eliminate PIM as well as optimize of medication use.
-
Key words:
- potentially inappropriate medication /
- nursing institution /
- poly-pharmacy
-
[1] 蹇在金.老年人用药六大原则[C].成都:第二届全国老年人内分泌代谢疾病学术会议论文汇编,2014:19-22. [2] Samuel M J.American geriatrics society 2015 updated beers criteria for potentially inappropriate medication use in older adults[J].J Am Geriatr Soc,2015,63(11):2227-2246. [3] GALLAGHER P F,O'CONNOR M N,O'MAHONY D.Prevention of potentially inappropriate prescribing for elderly patients:A randomized controlled trial using STOPP/START criteria[J].Clin Pharmacol Ther,2011,89(6):845-854. [4] 中国老年保健医学研究会老年合理用药分会.中国老年人潜在不适当用药判断标准(2017版)[J].药物不良反应杂志,2018,20(1):2-8. [5] 国务院.国务院关于加快发展养老服务业的若干意见[S].国发[2013]35号. [6] REISBERG B,FERRIS S H,DE LEON M J,et al. Global deterioration scale (GDS)[J].Psychopharmacol Bull,1988,24(4):661-663. [7] LU L,WANG S B,RAO W W,et al. Sleep duration and patterns in Chinese older adults:A comprehensive meta-analysis[J].Int J Biol Sci,2017,13(6):682-689. [8] 中华医学会神经病学分会,中华医学会神经病学分会睡眠障碍学组.中国成人失眠诊断与治疗指南(2017版)[J].中华神经科杂志,2018,51(5):324-335. [9] 中华医学会心血管病学会分会中华心血管病杂志编辑委员会.非ST段抬高急性冠状动脉综合征诊断和治疗指南(2016)[J].中华心血管病杂志,2017,45(5):359-375. [10] 徐晓燕,彭光海,范洁,等.稳定期老年精神分裂症患者社会认知特征与社会功能的相关性[J].中国老年学杂志,2018,38(17):4206-4208. [11] 曾裕培,陈伟忠,胡任重.非甾体抗炎药治疗老年人慢性疼痛研究及用药原则分析[J].海南医学院学报,2012,18(6):862-864. [12] 王靖宇,常宝成.高尿酸血症/痛风流行病学特点及危险因素[J].国际内分泌代谢杂志,2016,36(2):78-81.
计量
- 文章访问数: 3815
- HTML全文浏览量: 404
- PDF下载量: 409
- 被引次数: 0