多效胃镜乳的处方改进及稳定性考察
Improvement and stability of multi-effect gastroscope emulsion
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摘要: 目的: 改进多效胃镜乳的处方,提高多效胃镜乳的稳定性,控制制剂的质量。 方法: 通过外观质量、显微镜检、离心试验、耐寒耐热试验、常温留样以及含量测定等为指标,考察不同的乳化剂对多效胃镜乳质量的影响,确定最优处方。 结果: 以0.8%司盘-80、1.6%西黄蓍胶和5%司盘-80、2%CMC-Na配制的多效胃镜乳,稳定性好。 结论: 改进后的多效胃镜乳处方可应用于制剂生产。Abstract: Objective:To enhance the stability and control quality of the multi-effect gastroscope emulsion by improving the pre- scription of emulsion. Methods: The different prescriptiones of the multi-effect gastroscope emulsion were tested and evaluated by mi- croscopy,centrifugal experiment,cold-resistant/heat-resistant experiment,room temperature storage test as well as the content-determi- nation. Results: The emulsion with 0.8% span-80,1.6% tragacantha or with 5% span-80,2% CMC-Na has a good stability.Conclu- sion:The prescriptions of the multi-effect gastroscope emulsion can be applied to preparation production.
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Key words:
- multi-effect gastroscope emulsion /
- prescription improvement /
- stability
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