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2024 Vol. 42, No. 10

Cover Catalogue
Reviews
Noninvasive diagnosis and pharmacotherapy of metabolic dysfunction-associated steatotic liver disease
SUN Danni, HUANG Yong, ZHANG Jiabao, WANG Pei
2024, 42(10): 411-418. doi: 10.12206/j.issn.2097-2024.202403049
Abstract(7854) HTML (2711) PDF (925KB)(35)
Abstract:
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease globally, encompassing the entire spectrum of fatty liver pathogenesis. It progresses from simple steatosis to metabolic-associated steatohep...
Research progress on resistance mechanisms of carbapenem-resistant Enterobacteriaceae
QIAN Shuyu, LI Tiejun
2024, 42(10): 419-425. doi: 10.12206/j.issn.2097-2024.202405005
Abstract(6250) HTML (2302) PDF (928KB)(71)
Abstract:
Carbapenem-resistant Enterobacteriaceae (CRE) is an increasingly serious threat to human health worldwide. CRE usually carries multiple drug resistance genes, which limit the selection of therapeutic drugs, prolong treatment time, require higher trea...
Original articles
Anti-fatigue activity of selenium nanoparticles functionalized by polysaccharides from Pleurotus tuber-regium sclerotium
ZOU Si, WU Yanbin, WU Jinzhong, WU Jianguo, HUANG Jiaxing
2024, 42(10): 426-432. doi: 10.12206/j.issn.2097-2024.202206072
Abstract(6953) HTML (2052) PDF (1534KB)(25)
Abstract:
Objective  To investigate the anti-fatigue effect of PTR-SeNPs in vivo by measuring the muscle relative length of hindlimb, load-bearing swimming time as well as serum and liver indexes of mice.   Methods  48 male C57/BL6 mice were randomly assign...
Protective effect and mechanisms of neostigmine in combination with anisodamine against pulmonary oxygen toxicity
ZHANG Guangyu, DU Jing, LIU Mengzhen, ZHU Danni, YAN Hui, LIU Chong
2024, 42(10): 433-438, 444. doi: 10.12206/j.issn.2097-2024.202310049
Abstract(6201) HTML (1742) PDF (1813KB)(10)
Abstract:
Objective  Pulmonary oxygen poisoning resulting from hyperbaric oxygen, frequently occurs in specialized operations, without any current effective prevention or treatment measures. To elucidate the impact and mechanism of neostigmine (NEO) in combin...
Analysis of resistance situation and resistance genes of clinical isolates of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli
HUANG Yun, ZHANG Zhengyin, JIN Ying, ZHENG YiJing, LI Tiejun, SUN Lili
2024, 42(10): 439-444. doi: 10.12206/j.issn.2097-2024.202309059
Abstract(5785) HTML (1859) PDF (1359KB)(21)
Abstract:
Objective   To analyze the current status of anti-bacterial activity of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli clinically isolated from hospitalized patients, detect their related resistance genes, and provide reference for ...
Medicine & Clinical
Mining and research on the adverse event signal of exenatide microspheres based on FAERS database
ZHANG Lianqing, LUO Yan, YANG Ti, YAO Jiachen, LI Wenyan
2024, 42(10): 445-450. doi: 10.12206/j.issn.2097-2024.202403057
Abstract(3639) HTML (1032) PDF (952KB)(19)
Abstract:
Objective   To explore the risk signals of adverse events (ADE) in the use of exenatide microspheres by the FDA adverse event reporting system (FAERS), and provide reference for clinical rational drug use and drug safety.   Methods  With exenatide...
Pharmacy Administration
Efficacy and safety of nivolumab in the treatment of non-small cell lung cancer:a meta-analysis
LIU Liyan, YU Xiaocui, SUN Chuanduo
2024, 42(10): 451-456. doi: 10.12206/j.issn.2097-2024.202310044
Abstract(6695) HTML (1974) PDF (1250KB)(17)
Abstract:
Objective  To systematically evaluate the efficacy and safety of nivolumab in the treatment of non-small cell lung cancer.   Methods  PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure(CNKI), Weipu Chinese Science and Techno...