2023 Vol. 41, No. 5
Display Method:
2023, 41(5): 265-272, 320.
doi: 10.12206/j.issn.2097-2024.202207022
Abstract:
As a type of extracellular vesicles, exosomes are released by living cells and contain diverse bioactive molecules, including nucleic acids, proteins, lipids and metabolites. They play an important role in various physiological and pathological proce...
As a type of extracellular vesicles, exosomes are released by living cells and contain diverse bioactive molecules, including nucleic acids, proteins, lipids and metabolites. They play an important role in various physiological and pathological proce...
2023, 41(5): 273-276, 328.
doi: 10.12206/j.issn.2097-2024.202207111
Abstract:
Tetrodotoxin (TTX) is a neurotoxin found in puffer fish and other marine organisms. It has been used as an inhibitor of voltage-gated sodium channels (VGSCs), which could selectively bind to the α-subunit on the outer vestibule of VGSCs, preventing s...
Tetrodotoxin (TTX) is a neurotoxin found in puffer fish and other marine organisms. It has been used as an inhibitor of voltage-gated sodium channels (VGSCs), which could selectively bind to the α-subunit on the outer vestibule of VGSCs, preventing s...
2023, 41(5): 277-283, 290.
doi: 10.12206/j.issn.2097-2024.202208079
Abstract:
Tumor immunotherapy has become a new cancer treatment which has been expected to eliminate tumors. Immune checkpoint inhibitors, especially programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) antibodies, have achieved significant clinical...
Tumor immunotherapy has become a new cancer treatment which has been expected to eliminate tumors. Immune checkpoint inhibitors, especially programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) antibodies, have achieved significant clinical...
2023, 41(5): 284-290.
doi: 10.12206/j.issn.2097-2024.202205088
Abstract:
Heart failure (HF) is a global public health problem with high morbidity and mortality. Numerous studies have shown that HF is caused by severe disturbance of energy metabolism, resulting in insufficient cardiac energy supply. This lack of energy cou...
Heart failure (HF) is a global public health problem with high morbidity and mortality. Numerous studies have shown that HF is caused by severe disturbance of energy metabolism, resulting in insufficient cardiac energy supply. This lack of energy cou...
2023, 41(5): 291-295.
doi: 10.12206/j.issn.2097-2024.202302026
Abstract:
Objective To construct lipid nanoparticles DLin-LNP for mRNA delivery. Methods D Lin-LNP was prepared by thin film hydration method, and DLin-LNP/mRNA was further constructed by using EGFP-mRNA as model drug. The particle size, zeta potential, and...
2023, 41(5): 296-301.
doi: 10.12206/j.issn.2097-2024.202112001
Abstract:
Objective To study the mechanism of Shexiang Baoxin pill in the treatment of atherosclerosis, and to provide a theoretical basis for long-term clinical application. Methods The chemical components and targets of Shexiang Baoxin pill were coll...
2023, 41(5): 302-309.
doi: 10.12206/j.issn.2097-2024.202208106
Abstract:
Objective To investigate the mechanism of action of Huzhang Qingmai decoction (HZQMY) on the improvement of cognitive function in mice with chronic cerebral ischemia from the perspective of intestinal flora. Methods A mouse model of chronic cereb...
2023, 41(5): 310-315.
doi: 10.12206/j.issn.2097-2024.202210013
Abstract:
Objective To perform a visual bibliometric analysis of hot spots as well as areas of Brucella disease research by searching brucellosis related literature. Methods A thematic search was conducted in the web of science core set database using B...
2023, 41(5): 316-320.
doi: 10.12206/j.issn.2097-2024.202206044
Abstract:
Objective To study the cyclic peptides from sponge Reniochalina sp. under the guidance of mass spectrometry. Methods M ass spectrometry-guided procedural separation methods were used to track and isolate the cyclic peptides from the sponge genus R...
2023, 41(5): 321-324.
doi: 10.12206/j.issn.2097-2024.202207092
Abstract:
Objective To perform the pharmacognostic identification of Anoectochilus lylei and establish the foundation for its accurate identification and further development. Methods The macroscopic identification and microscopic identification methods we...
2023, 41(5): 325-328.
doi: 10.12206/j.issn.2097-2024.202211024
Abstract:
Objective To investigate the antioxidant and anti-inflammatory activities of four kinds of Huangshan chrysanthemum. Methods A BTS, FRAP and DPPH were used to detect the antioxidant activities of Huangshan golden silk chrysanthemum, Huangshan chrys...
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