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2023 Vol. 41, No. 4

Cover Catalogue
Display Method:
Research progress of tradition Chinese medicine treatment mechanism of systemic lupus erythematosus based on biomarkers
LIU Yaoyang, WU Xin, ZHOU Ling, ZHAO Ying, XU Huji
2023, 41(4): 197-201. doi: 10.12206/j.issn.2097-2024.202206131
Abstract(7444) HTML (2543) PDF (927KB)(53)
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement. There are still many limitations and individual differences in the treatment based on glucocorticoids and immunosuppressants. In recent years, more and more ...
Advances in preclinical studies on borneol as an adjuvant for glioma
XIA Jing, CHEN Hang, CHEN Jianming, WU Xin
2023, 41(4): 202-206. doi: 10.12206/j.issn.2097-2024.202203126
Abstract(5003) HTML (1411) PDF (901KB)(24)
Abstract:
Glioma is a common primary malignant brain tumor. At present, the main clinical treatment is surgical resection combined with radiotherapy and chemotherapy. Due to the selective permeability of the blood-brain barrier and the characteristics of multi...
Progress on the antitumor activity of cryptotanshinone and its derivatives
WEN Ping, ZHANG Junping
2023, 41(4): 207-211. doi: 10.12206/j.issn.2097-2024.202208090
Abstract(5300) HTML (3183) PDF (896KB)(29)
Abstract:
Cryptotanshinone is one of the effective components of traditional Chinese medicine salvia miltiorrhiza which shows good activities against a variety of tumors. Its anti-tumor effects include inhibition of tumor cell proliferation, induction of cell ...
Progress on drug delivery of iontophoresis
JIANG Weiwei, YANG Feng
2023, 41(4): 212-217, 233. doi: 10.12206/j.issn.2097-2024.202208008
Abstract(8776) HTML (3893) PDF (1426KB)(60)
Abstract:
Iontophoresis is a non-invasive physical permeation technology, which has been widely applied in transdermal and transmucosal administration. Compared with other permeation technologies, iontophoresis have the advantages of high efficacy, high patien...
Determination and effect of five alkaloids from extracts of Piper longum on rats with experimental myocardial ischemia induced by injection of pituitrin
YI Bowen, LIU Huining, ZHENG Rui, REN Jiawei, LIU Yang
2023, 41(4): 218-221, 264. doi: 10.12206/j.issn.2097-2024.202112011
Abstract(835) HTML (423) PDF (1517KB)(6)
Abstract:
Objective  To determine the content of five alkaloids from extracts of Piper longum and test the pharmacodynamic effect of them on rats with experimental myocardial ischemia induced by injection of pituitrin.   Methods  The content of five alkaloi...
Construction and expression of lentiviral vector overexpressing ZNF24 gene in human colorectal cancer HCT116 cell
TIAN Shuo, LI Jianzhong
2023, 41(4): 222-226. doi: 10.12206/j.issn.2097-2024.202204040
Abstract(4604) HTML (5622) PDF (2000KB)(62)
Abstract:
Objective  To establish the human colorectal cancer cell line HCT116 with ZNF24 gene overexpression by constructing lentiviral vector of ZNF24 gene overexpression, and provide material basis for subsequent research.   Methods  The recombinant expr...
Effects of specific knockdown of ribosomal protein S5 in hepatic stellate cells on liver fibrosis
TANG Yuzhen, ZHANG Junping
2023, 41(4): 227-233. doi: 10.12206/j.issn.2097-2024.202209007
Abstract(4113) HTML (2334) PDF (1768KB)(5)
Abstract:
Objective  To observe the effect of specific knockdown of hepatic stellate cells (HSC) ribosomal protein S5 (RPS5) on liver fibrosis in rats.   Methods  The glial fibrillary acidic protein (GFAP) promoter-driven RPS5 shRNA adenovirus was established,...
Inhibitory effects of gemcitabine hydrochloride combined with ferroptosis inducers on the proliferation of PANC-1 cells
WANG Jirong, YANG Daoqiu, SUN Zhiguo, HAN Han, DENG Li
2023, 41(4): 234-239. doi: 10.12206/j.issn.2097-2024.202212051
Abstract(3909) HTML (1729) PDF (1369KB)(23)
Abstract:
Objective  To study the effects of three ferroptosis inducers Erastin (Era), sulfasalazine (SASP) and artesunate (Art) alone or combined with gemcitabine hydrochloride (hcGEM) on the proliferation inhibition of Human pancreatic cell line PANC -1.   M...
Optimization of extraction process of prescription medicinal materials of compound Yangshe granules
YU Jianchao, MA Chao, WANG Mengmeng, LI Dan, LIU Rongmei, LIU Jiyong
2023, 41(4): 240-244. doi: 10.12206/j.issn.2097-2024.202207103
Abstract(4050) HTML (1236) PDF (1388KB)(6)
Abstract:
Objective  Optimizing the extraction process of prescription medicinal materials of hospital preparation of compound Yangshe granules.   Methods  A high performance liquid chromatograph (HPLC) quantitative method was established for deacetyl asperulo...
Discussion on the chemical compositions and treatment mechanism of sepsis of Sonchus arvensis L. by network pharmacology
HU Bingyue, ZHANG Xinkang, CEN Jinfeng, LV Chongning, LU Jincai, XIAO Kai
2023, 41(4): 245-251. doi: 10.12206/j.issn.2097-2024.202301001
Abstract(4738) HTML (2056) PDF (4168KB)(8)
Abstract:
Objective  To explore the effective constituents from Sonchus arvensis L. and the potential mechanism in treating sepsis by network pharmacology.   Methods  The chemical ingredients reported in the literature were taken as research objects and Swiss ...
Study on the efficacy of the resolving depression and tranquilizing TCM sachets in alleviating sleep disorders of soldiers in naval vessels
MENG Xiangqing, WEI Nini, HUANG Xiangchun, XU Jiacheng, DONG Wei, JIA Min
2023, 41(4): 252-254. doi: 10.12206/j.issn.2097-2024.202105063
Abstract(5324) HTML (1317) PDF (888KB)(11)
Abstract:
Objective  To explore the efficacy of the resolving depression and tranquilizing herbal sachets in alleviating sleep disorders of soldiers in naval vessels.   Methods  Fifty-nine soldiers with sleep disorders (PSQI scale score ≥8 and SAS scale sco...
Practice and experience of clinical pharmacists participating in pharmaceutical care for patients after heart valve replacement
LI Ying, QIAN Jiao, ZHU Quangang
2023, 41(4): 255-258. doi: 10.12206/j.issn.2097-2024.202201087
Abstract(3813) HTML (1281) PDF (867KB)(28)
Abstract:
Objective  To explore the starting point of pharmaceutical care by clinical pharmacists for patients after heart valve replacement.   Methods  Combined with typical cases, the content, focus and effects of pharmaceutical care for patients after he...
Construction of the evaluation index system for pharmacist training effectiveness based on Kirkpatrick evaluation model
YIN Jie, CHEN Yongfa
2023, 41(4): 259-264. doi: 10.12206/j.issn.2097-2024.202105056
Abstract(2966) HTML (3008) PDF (967KB)(11)
Abstract:
Objective  To construct the evaluation index system for pharmacist training effectiveness in China.   Methods  The initial framework of index system based on Kirkpatrick evaluation model was constructed through literature research and expert inter...