2023 Vol. 41, No. 4
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2023, 41(4): 197-201.
doi: 10.12206/j.issn.2097-2024.202206131
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement. There are still many limitations and individual differences in the treatment based on glucocorticoids and immunosuppressants. In recent years, more and more ...
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement. There are still many limitations and individual differences in the treatment based on glucocorticoids and immunosuppressants. In recent years, more and more ...
2023, 41(4): 202-206.
doi: 10.12206/j.issn.2097-2024.202203126
Abstract:
Glioma is a common primary malignant brain tumor. At present, the main clinical treatment is surgical resection combined with radiotherapy and chemotherapy. Due to the selective permeability of the blood-brain barrier and the characteristics of multi...
Glioma is a common primary malignant brain tumor. At present, the main clinical treatment is surgical resection combined with radiotherapy and chemotherapy. Due to the selective permeability of the blood-brain barrier and the characteristics of multi...
2023, 41(4): 207-211.
doi: 10.12206/j.issn.2097-2024.202208090
Abstract:
Cryptotanshinone is one of the effective components of traditional Chinese medicine salvia miltiorrhiza which shows good activities against a variety of tumors. Its anti-tumor effects include inhibition of tumor cell proliferation, induction of cell ...
Cryptotanshinone is one of the effective components of traditional Chinese medicine salvia miltiorrhiza which shows good activities against a variety of tumors. Its anti-tumor effects include inhibition of tumor cell proliferation, induction of cell ...
2023, 41(4): 212-217, 233.
doi: 10.12206/j.issn.2097-2024.202208008
Abstract:
Iontophoresis is a non-invasive physical permeation technology, which has been widely applied in transdermal and transmucosal administration. Compared with other permeation technologies, iontophoresis have the advantages of high efficacy, high patien...
Iontophoresis is a non-invasive physical permeation technology, which has been widely applied in transdermal and transmucosal administration. Compared with other permeation technologies, iontophoresis have the advantages of high efficacy, high patien...
2023, 41(4): 218-221, 264.
doi: 10.12206/j.issn.2097-2024.202112011
Abstract:
Objective To determine the content of five alkaloids from extracts of Piper longum and test the pharmacodynamic effect of them on rats with experimental myocardial ischemia induced by injection of pituitrin. Methods The content of five alkaloi...
2023, 41(4): 222-226.
doi: 10.12206/j.issn.2097-2024.202204040
Abstract:
Objective To establish the human colorectal cancer cell line HCT116 with ZNF24 gene overexpression by constructing lentiviral vector of ZNF24 gene overexpression, and provide material basis for subsequent research. Methods The recombinant expr...
2023, 41(4): 227-233.
doi: 10.12206/j.issn.2097-2024.202209007
Abstract:
Objective To observe the effect of specific knockdown of hepatic stellate cells (HSC) ribosomal protein S5 (RPS5) on liver fibrosis in rats. Methods T he glial fibrillary acidic protein (GFAP) promoter-driven RPS5 shRNA adenovirus was established,...
2023, 41(4): 234-239.
doi: 10.12206/j.issn.2097-2024.202212051
Abstract:
Objective To study the effects of three ferroptosis inducers Erastin (Era), sulfasalazine (SASP) and artesunate (Art) alone or combined with gemcitabine hydrochloride (hcGEM) on the proliferation inhibition of Human pancreatic cell line PANC -1. M...
2023, 41(4): 240-244.
doi: 10.12206/j.issn.2097-2024.202207103
Abstract:
Objective Optimizing the extraction process of prescription medicinal materials of hospital preparation of compound Yangshe granules. Methods A high performance liquid chromatograph (HPLC) quantitative method was established for deacetyl asperulo...
2023, 41(4): 245-251.
doi: 10.12206/j.issn.2097-2024.202301001
Abstract:
Objective To explore the effective constituents from Sonchus arvensis L. and the potential mechanism in treating sepsis by network pharmacology. Methods T he chemical ingredients reported in the literature were taken as research objects and Swiss ...
2023, 41(4): 252-254.
doi: 10.12206/j.issn.2097-2024.202105063
Abstract:
Objective To explore the efficacy of the resolving depression and tranquilizing herbal sachets in alleviating sleep disorders of soldiers in naval vessels. Methods Fifty-nine soldiers with sleep disorders (PSQI scale score ≥8 and SAS scale sco...
2023, 41(4): 255-258.
doi: 10.12206/j.issn.2097-2024.202201087
Abstract:
Objective To explore the starting point of pharmaceutical care by clinical pharmacists for patients after heart valve replacement. Methods Combined with typical cases, the content, focus and effects of pharmaceutical care for patients after he...
2023, 41(4): 259-264.
doi: 10.12206/j.issn.2097-2024.202105056
Abstract:
Objective To construct the evaluation index system for pharmacist training effectiveness in China. Methods The initial framework of index system based on Kirkpatrick evaluation model was constructed through literature research and expert inter...