2023 Vol. 41, No. 12
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2023, 41(12): 705-709, 732.
doi: 10.12206/j.issn.2097-2024.202211025
Abstract:
As a highly malignant tumor, the diagnosis of cholangiocarcinoma (CCA) is often late and the prognosis is poor for which the early symptoms are atypical and the lack of accurate biomarkers. Metabolomics is an emerging science that researches the alte...
As a highly malignant tumor, the diagnosis of cholangiocarcinoma (CCA) is often late and the prognosis is poor for which the early symptoms are atypical and the lack of accurate biomarkers. Metabolomics is an emerging science that researches the alte...
2023, 41(12): 710-713, 721.
doi: 10.12206/j.issn.2097-2024.202204043
Abstract:
The transcription factor ZNF24 (also known as ZNF191 or KOX17) is a member of the Krüppel-like zinc finger transcription factor family, with a leucine-rich (Leu) SCAN domain (also known as LeR domain) at the N-terminus and four consecutive typical Kr...
The transcription factor ZNF24 (also known as ZNF191 or KOX17) is a member of the Krüppel-like zinc finger transcription factor family, with a leucine-rich (Leu) SCAN domain (also known as LeR domain) at the N-terminus and four consecutive typical Kr...
2023, 41(12): 714-721.
doi: 10.12206/j.issn.2097-2024.202209051
Abstract:
Objective To explore the potential mechanism of artemisinin in the treatment of polycystic ovary syndrome (PCOS) by network pharmacology and molecular docking technology. Methods The corresponding targets of natural product artemisinin were ob...
2023, 41(12): 722-732.
doi: 10.12206/j.issn.2097-2024.202302001
Abstract:
Objective To analyze the main active components and potential molecular mechanism of Sophora flavescens against breast cancer based on network pharmacology and molecular docking. Methods The chemical constituents were collected and screened by...
2023, 41(12): 733-736.
doi: 10.12206/j.issn.2097-2024.202208022
Abstract:
Objective To conduct in vitro transdermal test on triamcinolone acetonide spray solution, and investigate the effects of ethanol and propylene glycol alone or in combination on the in vitro transdermal function of triamcinolone acetonide spray solu...
2023, 41(12): 737-740.
doi: 10.12206/j.issn.2097-2024.202303021
Abstract:
Objective To find a more effective alternative therapy for antibiotic therapy and fecal microbiota transplantation in current primary treatment of clostridioides difficile infection (CDI) because of the high recurrence rate. Methods A series of...
2023, 41(12): 741-746.
doi: 10.12206/j.issn.2097-2024.202206052
Abstract:
Objective To evaluate the release characteristics in vitro, pharmacokinetics in rabbits and in vivo-in vitro correlation of silymarin phospholipid complex microporous osmotic pump controlled release tablets（SM-PC MPOP）. Methods The release char...
2023, 41(12): 747-752, 759.
doi: 10.12206/j.issn.2097-2024.202208101
Abstract:
Objective To explore the regularity of traditional Chinese medicine (TCM) in the treatment of postembolization syndrome (PES) after transcatheter arterial chemoembolization (TACE). Methods CNKI, WANFANG and VIP were used as data sources to sea...
2023, 41(12): 753-759.
doi: 10.12206/j.issn.2097-2024.202302040
Abstract:
Objective To screen potential metabolites and significantly altered metabolic pathways of liver lesions by central carbon pathway metabolites. Methods 32 healthy volunteers (HC), 23 patients with biliary cysts (CYST), 19 patients with biliary ...
2023, 41(12): 760-762.
doi: 10.12206/j.issn.2097-2024.202204122
Abstract:
Objective To investigate the antithrombotic therapy for acute myocardial infarction patients after PCI stenting combined with tricuspid valve repair. Methods The risk of bleeding and embolization was evaluated, relevant data were reviewed, pro...
2023, 41(12): 763-766.
doi: 10.12206/j.issn.2097-2024.202208080
Abstract:
Objective To explore the effect of metformin hydrochloride tablets on the clinical efficacy, number of dominant follicles and ovarian volume of polycystic ovary syndrome. Methods 150 patients diagnosed with polycystic ovary syndrome who were d...
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