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2023 Vol. 41, No. 11

Cover Catalogue
Display Method:
Research progress on therapeutic DC vaccine against melanoma
ZHANG Xinyue, TAI Zongguang, ZHU Quangang, CHEN Zhongjian, BAO Leilei
2023, 41(11): 643-647. doi: 10.12206/j.issn.2097-2024.202211043
Abstract(5054) HTML (2422) PDF (853KB)(38)
Abstract:
Melanoma is the most aggressive skin malignant tumor, which is prone to early metastasis and relapse after treatment. Therapeutic tumor vaccines are new immunotherapies, which have the advantages of low toxicity and inhibiting tumor metastasis. Melan...
Progress on factors affecting gastrointestinal function and drug protection in high altitude hypoxia environment
CHENG Junfei, ZHAO Anpeng, ZHAO Yilan, WANG Zihan, LI Wenbin, WANG Rong
2023, 41(11): 648-653. doi: 10.12206/j.issn.2097-2024.202111018
Abstract(6345) HTML (3579) PDF (1243KB)(97)
Abstract:
Due to factors such as low pressure, low oxygen and cold in the plateau environment, people who enter the plateau rapidly are susceptible to digestive system diseases, such as upper abdominal pain, loss of appetite, nausea and vomiting and other gast...
Effect of intestinal Metrnl gene knockout on intestinal microbiota and ulcerative colitis
CHEN Simin, LING Qisheng, ZHANG Sailong, MIAO Chaoyu
2023, 41(11): 654-661. doi: 10.12206/j.issn.2097-2024.202211050
Abstract(4337) HTML (2522) PDF (2729KB)(23)
Abstract:
Objective  To investigate the effect of intestinal Metrnl on dextran sodium sulfate (DSS)-induced ulcerative colitis mouse model and the regulation mechanism of intestinal microbiota.   Methods  Different concentrations of DSS (3% DSS and 1% DSS) ...
TLC identification and quantitative determination of Shipi Xiaoshui gel plaster
MA Bingzhi, LIANG Yingying, WANG Haiyang, TANG Yonghe, LI Dong, HE Jun
2023, 41(11): 662-665, 679. doi: 10.12206/j.issn.2097-2024.202205054
Abstract(3579) HTML (1150) PDF (1780KB)(13)
Abstract:
Objective   To establish the method of thin layer chromatography (TLC) for identification and quantitative determination of Shipi Xiaoshui gel plaster.   Methods  TLC was adopted to qualitatively identify astragalus radix, plantaginis semen, curcu...
Protective effect of Shenmajing formula on ischemic brain injury in mice
LIU Jingxue, HE Ruihua, TAO Xia, HUANG Jin
2023, 41(11): 666-671, 685. doi: 10.12206/j.issn.2097-2024.202208066
Abstract(2844) HTML (1456) PDF (2968KB)(14)
Abstract:
Objective   To observe the protective effect of Shenmajing formula on brain tissue of mice with cerebral ischemic injury and explore the possible mechanism.   Methods  Thirty SPF-grade C57 BL/6 male mice were randomly divided into model control gr...
Mechanism of Artemisia annua L. in GIOP with kidney-yin deficiency based on network pharmacology
LAI Liyong, XIA Tianshuang, YUE Xiaoqiang, XIN Hailiang
2023, 41(11): 672-679. doi: 10.12206/j.issn.2097-2024.202204115
Abstract(2941) HTML (1980) PDF (3112KB)(21)
Abstract:
Objective  To predict and preliminarily verify the potential targets and related signaling pathways of Artemisia annua L. in treating glucocorticoid-induced osteoporosis (GIOP) with kidney-yin deficiency by network pharmacology and in vitro experime...
Review of clinical use of Dingqing Tablets in a Tertiary A Hospital of Integrated Traditional Chinese and Western Medicine
XU Yi, YANG Yuehong, HUANG Jin, WANG Jie, LIU Jing, WU Tiejun
2023, 41(11): 680-685. doi: 10.12206/j.issn.2097-2024.202208034
Abstract(3085) HTML (1208) PDF (1110KB)(22)
Abstract:
Objective  To improve the quality of prescriptions and promote the rational drug application of Dingqing Tablets by investigating the outpatient prescriptions in a tertiary A hospital.   Methods  A total of 4 796 prescriptions of outpatient pharma...
Effect evaluation of the clinical pharmacists participating in the treatment of patients with diabetic foot
YANG Zhihui, ZHANG Lili, ZHAO Yan, HUANG Jinghui, LIU Yuan, YUAN Hailong
2023, 41(11): 686-688, 699. doi: 10.12206/j.issn.2097-2024.202209087
Abstract(2899) HTML (1592) PDF (1185KB)(18)
Abstract:
Objective  To evaluate the effect of clinical pharmacists participating in the treatment of hospitalized patients with diabetic foot by antibiotics management index and health economics index.   Methods  40 hospitalized patients with diabetic foot...
Practice and exploration of physician-pharmacist joint outpatient service mode of chronic obstructive pulmonary disease (COPD) and asthma
CHEN Dan, LIU Guodong, LIU Yu, TONG Shaohua, LIU Shengjun
2023, 41(11): 689-693. doi: 10.12206/j.issn.2097-2024.202209034
Abstract(4114) HTML (1536) PDF (1016KB)(31)
Abstract:
Objective   To explore the physician-pharmacist joint outpatient service mode of chronic obstructive pulmonary disease ( COPD) and asthma.   Methods  Cases of COPD or asthma patients who visited the joint outpatient department from June 2021 to De...
Risk factors of linezolid-related thrombocytopenia in patients in the department of hepatobiliary surgery
SHAN Xuechun, LI Xu, DU Hongli, BAO Leilei, WANG Hui
2023, 41(11): 694-699. doi: 10.12206/j.issn.2097-2024.202210061
Abstract(4360) HTML (1647) PDF (957KB)(12)
Abstract:
Objective  To provide the evidence for clinical medication safety by the investigation of the risk factors of linezolid-related thrombocytopenia in cancer patients in the department of hepatobiliary surgery.   Methods  Patients who received linezo...
Risk factors of poor early prognosis in the treatment of COVID-19 with nematevir and ritonavir tablets and the establishment of prediction model
HUANG Wenhui, XU Yanyu, HAO Xiaowei, LIN Guan, OUYANG Shandan, WANG Jiakun, CHEN Jinshan
2023, 41(11): 700-704. doi: 10.12206/j.issn.2097-2024.202303038
Abstract(4314) HTML (1360) PDF (971KB)(15)
Abstract:
Objective  To explore risk factors of poor early prognosis in the treatment of COVID-19 by nematevir and ritonavir tablets Paxlovid and establish the prediction model to provide reference for improving the effect of such patients.   Methods  92 in...