2023 Vol. 41, No. 10
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2023, 41(10): 581-585, 628.
doi: 10.12206/j.issn.2097-2024.202109068
Abstract:
Diabetic nephropathy (DN) is a common microvascular complication of type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), which is also the main cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, the tre...
Diabetic nephropathy (DN) is a common microvascular complication of type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), which is also the main cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, the tre...
2023, 41(10): 586-593.
doi: 10.12206/j.issn.2097-2024.202307047
Abstract:
Liver cancer is the second leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (HCC) being the most common form of primary liver cancer. Glypican-3 (GPC3) is a cell membrane proteoglycan which is rarely expressed in normal...
Liver cancer is the second leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (HCC) being the most common form of primary liver cancer. Glypican-3 (GPC3) is a cell membrane proteoglycan which is rarely expressed in normal...
2023, 41(10): 594-599.
doi: 10.12206/j.issn.2097-2024.202307027
Abstract:
Objective To prepare and optimize the formulation of Albumin nanoparticles loading PROTAC molecule and observe the inhibition effect of nanoparticles on the proliferation and NAD+ metabolism of glioma cells. Methods Albumin nanoparticles loadi...
2023, 41(10): 600-609.
doi: 10.12206/j.issn.2097-2024.202212049
Abstract:
Objective To investigate the material basis and antitumor mechanism of Marsdenia tenacissima (MT) on hepatocellular carcinoma (HCC) by bioinformatics, network pharmacology and molecular docking technology. Methods Active ingredients of MT were...
2023, 41(10): 610-615.
doi: 10.12206/j.issn.2097-2024.202305035
Abstract:
Objective To study the antifungal activity of N2 derivatives. Methods The anti-fungal activity of N2 compounds was investigated by micro-liquid dilution. Then the activity of N2 compounds on hyphal and biofilm formation was investigated. Re...
2023, 41(10): 616-624.
doi: 10.12206/j.issn.2097-2024.202306022
Abstract:
Objective To predict the target of Atractylodes-Panxia-Poria in the treatment of pancreatic cancer, and to explore its potential molecular mechanism by using network pharmacology and molecular docking. Methods Traditional Chinese Medicine Syst...
2023, 41(10): 625-628.
doi: 10.12206/j.issn.2097-2024.202107024
Abstract:
Objective To investigate the pathogenesis of superficial mycosis among naval trainees, and observe the efficacy of a novel antifungal drug. Methods A questionnaire survey was conducted on the onset, medication and recurrence of superficial fun...
2023, 41(10): 629-633, 642.
doi: 10.12206/j.issn.2097-2024.202207087
Abstract:
Objective To develop a pharmacogenomics study of ticagrelor in patients with acute coronary syndrome (ACS), identify the genetic factors that can predict individual differences in antiplatelet aggregation effects of ticagrelor, and provide a refere...
2023, 41(10): 634-637.
doi: 10.12206/j.issn.2097-2024.202108129
Abstract:
Objective To investigate the correlation between plasma inflammatory factors [IL-1β, IL-6, IL-10, IL-12, IL-17, IL-23, TNF-α, TGF-β, IFN-γ, C-reactive protein (CPR) CCL-5] and hand-foot syndrome in colorectal cancer patients after taking capecitabi...
2023, 41(10): 638-642.
doi: 10.12206/j.issn.2097-2024.202206087
Abstract:
Objective To explore the effect midazolam combination with propofol on postoperative recovery in patients undergoing laparoscopic cholecystectomy. Methods A total of 162 patients who were admitted to the hospital for laparoscopic cholecystecto...
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